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EFR LRR receptor-like serine/threonine-protein kinase EFR [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832170, updated on 7-Sep-2014
Gene symbol
EFR
Gene description
LRR receptor-like serine/threonine-protein kinase EFR
Primary source
TAIR:AT5G20480
Locus tag
AT5G20480
Gene type
protein coding
RNA name
LRR receptor-like serine/threonine-protein kinase EFR
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EF-TU receptor; EFR; F7C8.70; F7C8_70
See EFR in MapViewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (6922480..6925887)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene putative myosin Neighboring gene Myosin XI K Neighboring gene glutaredoxin-C4 Neighboring gene alfin-like 5 protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Plant-pathogen interaction, organism-specific biosystem (from KEGG)
    Plant-pathogen interaction, organism-specific biosystemPlants lack animal-like adaptive immunity mechanisms, and therefore have evolved a specific system with multiple layers against invading pathogens. The primary response includes the perception of pat...
  • Plant-pathogen interaction, conserved biosystem (from KEGG)
    Plant-pathogen interaction, conserved biosystemPlants lack animal-like adaptive immunity mechanisms, and therefore have evolved a specific system with multiple layers against invading pathogens. The primary response includes the perception of pat...
Products Interactant Other Gene Complex Source Pubs Description
  • Encodes a predicted leucine-rich repeat receptor kinase (LRR-RLK). Functions as the receptor for bacterial PAMP (pathogen associated molecular patterns) EF-Tu.
NM_122055.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
ATP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
transmembrane receptor protein kinase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
MAPK cascade RCA
inferred from Reviewed Computational Analysis
more info
 
defense response signaling pathway, resistance gene-independent IMP
Inferred from Mutant Phenotype
more info
PubMed 
defense response to bacterium RCA
inferred from Reviewed Computational Analysis
more info
 
defense response to fungus RCA
inferred from Reviewed Computational Analysis
more info
 
detection of bacterium IDA
Inferred from Direct Assay
more info
PubMed 
detection of bacterium RCA
inferred from Reviewed Computational Analysis
more info
 
detection of biotic stimulus RCA
inferred from Reviewed Computational Analysis
more info
 
detection of external stimulus RCA
inferred from Reviewed Computational Analysis
more info
 
immune response-regulating signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
jasmonic acid mediated signaling pathway RCA
inferred from Reviewed Computational Analysis
more info
 
negative regulation of defense response RCA
inferred from Reviewed Computational Analysis
more info
 
plant-type hypersensitive response IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
protein targeting to membrane RCA
inferred from Reviewed Computational Analysis
more info
 
regulation of anion channel activity IMP
Inferred from Mutant Phenotype
more info
 
regulation of defense response RCA
inferred from Reviewed Computational Analysis
more info
 
regulation of hydrogen peroxide metabolic process RCA
inferred from Reviewed Computational Analysis
more info
 
regulation of immune response RCA
inferred from Reviewed Computational Analysis
more info
 
regulation of multi-organism process RCA
inferred from Reviewed Computational Analysis
more info
 
regulation of plant-type hypersensitive response RCA
inferred from Reviewed Computational Analysis
more info
 
response to chitin RCA
inferred from Reviewed Computational Analysis
more info
 
salicylic acid biosynthetic process RCA
inferred from Reviewed Computational Analysis
more info
 
systemic acquired resistance, salicylic acid mediated signaling pathway RCA
inferred from Reviewed Computational Analysis
more info
 
transmembrane receptor protein tyrosine kinase signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
plasma membrane ISM
Inferred from Sequence Model
more info
 
Names
LRR receptor-like serine/threonine-protein kinase EFR
NP_197548.1
  • EF-TU receptor (EFR); FUNCTIONS IN: protein serine/threonine kinase activity, transmembrane receptor protein kinase activity, kinase activity, ATP binding; INVOLVED IN: in 7 processes; LOCATED IN: endomembrane system; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat protein kinase family protein (TAIR:AT3G47090.1); Has 211073 Blast hits to 132033 proteins in 4602 species: Archae - 167; Bacteria - 19808; Metazoa - 69159; Fungi - 9873; Plants - 87247; Viruses - 333; Other Eukaryotes - 24486 (source: NCBI BLink).

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 

    Range
    6922480..6925887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_122055.4NP_197548.1  LRR receptor-like serine/threonine-protein kinase EFR [Arabidopsis thaliana]

    See proteins identical to NP_197548.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C0LGT6
    Conserved Domains (4) summary
    cd00180
    Location:718924
    PKc; Catalytic domain of Protein Kinases
    PLN00113
    Location:201006
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    cd00116
    Location:394597
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam08263
    Location:2868
    LRRNT_2; Leucine rich repeat N-terminal domain