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Jup junction plakoglobin [ Mus musculus (house mouse) ]

Gene ID: 16480, updated on 19-Jul-2014
Official Symbol
Jupprovided by MGI
Official Full Name
junction plakoglobinprovided by MGI
Primary source
MGI:96650
Locus tag
RP23-392I3.6
See related
Ensembl:ENSMUSG00000001552; Vega:OTTMUSG00000006276
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PG; Ctnng; D930025P04Rik
Location:
11 D; 11 63.47 cM
Exon count:
15
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 11 NC_000077.6 (100368856..100397790, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene huntingtin-associated protein 1 Neighboring gene ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c, isoform 1 pseudogene Neighboring gene uncharacterized LOC102635937 Neighboring gene leprecan-like 4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
alpha-catenin binding IPI
Inferred from Physical Interaction
more info
PubMed 
alpha-catenin binding ISO
Inferred from Sequence Orthology
more info
 
cadherin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
cadherin binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
structural molecule activity IBA
Inferred from Biological aspect of Ancestor
more info
 
structural molecule activity ISO
Inferred from Sequence Orthology
more info
 
transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
atrioventricular valve morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
bundle of His cell to Purkinje myocyte communication ISO
Inferred from Sequence Orthology
more info
 
cell adhesion IDA
Inferred from Direct Assay
more info
PubMed 
cell migration ISO
Inferred from Sequence Orthology
more info
 
cell morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
cellular response to indole-3-methanol ISO
Inferred from Sequence Orthology
more info
 
cytoskeletal anchoring at plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
desmosome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
desmosome assembly ISO
Inferred from Sequence Orthology
more info
 
detection of mechanical stimulus ISO
Inferred from Sequence Orthology
more info
 
ectoderm development IBA
Inferred from Biological aspect of Ancestor
more info
 
establishment of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
gastrulation IBA
Inferred from Biological aspect of Ancestor
more info
 
morphogenesis of embryonic epithelium IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of Wnt signaling pathway involved in heart development IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of heart induction by canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
 
oocyte development IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of protein import into nucleus ISO
Inferred from Sequence Orthology
more info
 
positive regulation of sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
protein heterooligomerization ISO
Inferred from Sequence Orthology
more info
 
regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of heart rate by cardiac conduction ISO
Inferred from Sequence Orthology
more info
 
single organismal cell-cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
single organismal cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
skin development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ventricular cardiac muscle cell action potential ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Z disc IDA
Inferred from Direct Assay
more info
PubMed 
actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
colocalizes_with actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
apicolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
beta-catenin destruction complex IBA
Inferred from Biological aspect of Ancestor
more info
 
catenin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
catenin complex ISO
Inferred from Sequence Orthology
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell-cell adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell adherens junction ISO
Inferred from Sequence Orthology
more info
 
cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
desmosome IDA
Inferred from Direct Assay
more info
PubMed 
desmosome IMP
Inferred from Mutant Phenotype
more info
PubMed 
desmosome ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
fascia adherens IBA
Inferred from Biological aspect of Ancestor
more info
 
fascia adherens ISO
Inferred from Sequence Orthology
more info
 
gamma-catenin-TCF7L2 complex ISO
Inferred from Sequence Orthology
more info
 
intercalated disc ISO
Inferred from Sequence Orthology
more info
 
intermediate filament IDA
Inferred from Direct Assay
more info
PubMed 
lateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
protein-DNA complex ISO
Inferred from Sequence Orthology
more info
 
zonula adherens IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
junction plakoglobin
Names
junction plakoglobin
desmoplakin-3
gamma-catenin
desmoplakin III

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010593.2NP_034723.1  junction plakoglobin

    See proteins identical to NP_034723.1

    Status: VALIDATED

    Source sequence(s)
    AK145895, AL590968, CD555608
    Consensus CDS
    CCDS25420.1
    UniProtKB/Swiss-Prot
    Q02257
    Conserved Domains (1) summary
    cd00020
    Location:476613
    Blast Score: 187
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000077.6 

    Range
    100368856..100397790
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532315.1XP_006532378.1  

    See proteins identical to XP_006532378.1

    UniProtKB/Swiss-Prot
    Q02257
    Related
    ENSMUSP00000001592, OTTMUSP00000006595, ENSMUST00000001592, OTTMUST00000014199
    Conserved Domains (1) summary
    cd00020
    Location:476613
    Blast Score: 187
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
  2. XM_006532316.1XP_006532379.1  

    See proteins identical to XP_006532379.1

    UniProtKB/Swiss-Prot
    Q02257
    Conserved Domains (1) summary
    cd00020
    Location:476613
    Blast Score: 187
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
  3. XM_006532317.1XP_006532380.1  

    Related
    ENSMUSP00000103026, OTTMUSP00000006596, ENSMUST00000107403, OTTMUST00000014200
    Conserved Domains (1) summary
    cd00020
    Location:476613
    Blast Score: 182
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

Alternate Mm_Celera

Genomic

  1. AC_000033.1 

    Range
    110986251..111016209
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)