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Adcyap1 adenylate cyclase activating polypeptide 1 [ Mus musculus (house mouse) ]

Gene ID: 11516, updated on 11-Sep-2014
Official Symbol
Adcyap1provided by MGI
Official Full Name
adenylate cyclase activating polypeptide 1provided by MGI
Primary source
MGI:105094
See related
Ensembl:ENSMUSG00000024256
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PACAP
See Adcyap1 in Epigenomics, MapViewer
Location:
17 E5; 17
Exon count:
7
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 17 NC_000083.6 (93198904..93206539)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene actin, gamma, cytoplasmic 1 pseudogene Neighboring gene pyruvate kinase, muscle pseudogene Neighboring gene uncharacterized LOC102635025 Neighboring gene ribosomal protein L3 pseudogene Neighboring gene PWP1 homolog pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
hormone activity IEA
Inferred from Electronic Annotation
more info
 
neuropeptide hormone activity ISO
Inferred from Sequence Orthology
more info
 
neuropeptide hormone activity TAS
Traceable Author Statement
more info
PubMed 
peptide hormone receptor binding ISO
Inferred from Sequence Orthology
more info
 
pituitary adenylate cyclase activating polypeptide activity IDA
Inferred from Direct Assay
more info
PubMed 
pituitary adenylate cyclase activating polypeptide activity ISO
Inferred from Sequence Orthology
more info
 
pituitary adenylate cyclase-activating polypeptide receptor binding ISO
Inferred from Sequence Orthology
more info
 
receptor binding ISO
Inferred from Sequence Orthology
more info
 
receptor signaling protein activity IDA
Inferred from Direct Assay
more info
PubMed 
receptor signaling protein activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
ATP metabolic process ISO
Inferred from Sequence Orthology
more info
 
activation of adenylate cyclase activity TAS
Traceable Author Statement
more info
PubMed 
behavioral fear response ISO
Inferred from Sequence Orthology
more info
 
cAMP-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
histamine secretion ISO
Inferred from Sequence Orthology
more info
 
intracellular signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of Rho GTPase activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of acute inflammatory response to antigenic stimulus ISO
Inferred from Sequence Orthology
more info
 
negative regulation of acute inflammatory response to non-antigenic stimulus ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cell cycle IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of glial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of muscle cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of potassium ion transport ISO
Inferred from Sequence Orthology
more info
 
nervous system development IEA
Inferred from Electronic Annotation
more info
 
neuron projection development ISO
Inferred from Sequence Orthology
more info
 
neuropeptide signaling pathway ISO
Inferred from Sequence Orthology
more info
 
neuropeptide signaling pathway TAS
Traceable Author Statement
more info
PubMed 
ovarian follicle development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of Rap GTPase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cAMP biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of gene expression IDA
Inferred from Direct Assay
more info
 
positive regulation of growth hormone secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of interleukin-6 production ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of somatostatin secretion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of synaptic transmission, glutamatergic ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
positive regulation of vasodilation ISO
Inferred from Sequence Orthology
more info
 
regulation of G-protein coupled receptor protein signaling pathway ISO
Inferred from Sequence Orthology
more info
 
regulation of oligodendrocyte progenitor proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of postsynaptic membrane potential ISO
Inferred from Sequence Orthology
more info
 
regulation of protein localization IDA
Inferred from Direct Assay
more info
PubMed 
regulation of protein localization ISO
Inferred from Sequence Orthology
more info
 
sensory perception of pain ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
intracellular ISO
Inferred from Sequence Orthology
more info
 
terminal bouton ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
pituitary adenylate cyclase-activating polypeptide
Names
pituitary adenylate cyclase-activating polypeptide

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009625.2NP_033755.1  pituitary adenylate cyclase-activating polypeptide precursor

    See proteins identical to NP_033755.1

    Status: PROVISIONAL

    Source sequence(s)
    BC057344
    Consensus CDS
    CCDS29029.1
    UniProtKB/Swiss-Prot
    O70176
    UniProtKB/TrEMBL
    Q3UYH8
    Related
    ENSMUSP00000067057, ENSMUST00000064775
    Conserved Domains (2) summary
    smart00070
    Location:131157
    GLUCA; Glucagon like hormones
    cl02450
    Location:82108
    Hormone_2; Peptide hormone

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000083.6 

    Range
    93198904..93206539
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523497.1XP_006523560.1  

    See proteins identical to XP_006523560.1

    Conserved Domains (1) summary
    smart00070
    Location:150176
    GLUCA; Glucagon like hormones
  2. XM_006523498.1XP_006523561.1  

    See proteins identical to XP_006523561.1

    Conserved Domains (1) summary
    smart00070
    Location:150176
    GLUCA; Glucagon like hormones
  3. XM_006523499.1XP_006523562.1  

    Conserved Domains (1) summary
    smart00070
    Location:123149
    GLUCA; Glucagon like hormones

Alternate Mm_Celera

Genomic

  1. AC_000039.1 

    Range
    97603693..97609773
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)