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Vdr vitamin D receptor [ Mus musculus (house mouse) ]

Gene ID: 22337, updated on 24-Apr-2015
Official Symbol
Vdrprovided by MGI
Official Full Name
vitamin D receptorprovided by MGI
Primary source
MGI:MGI:103076
See related
Ensembl:ENSMUSG00000022479; Vega:OTTMUSG00000026431
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nr1i1
Orthologs
See Vdr in MapViewer
Location:
15; 15 F1
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (97854427..97908296, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (97684858..97738727, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 48 (heme transporter), member 1 Neighboring gene histone deacetylase 7 Neighboring gene predicted gene, 33636 Neighboring gene predicted gene, 33690 Neighboring gene transmembrane protein 106C Neighboring gene collagen, type II, alpha 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
calcitriol binding ISO
Inferred from Sequence Orthology
more info
 
calcitriol receptor activity ISO
Inferred from Sequence Orthology
more info
 
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
lithocholic acid binding ISO
Inferred from Sequence Orthology
more info
 
lithocholic acid receptor activity ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
retinoid X receptor binding ISO
Inferred from Sequence Orthology
more info
 
sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
steroid hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
vitamin D binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to vitamin D response element binding ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
bile acid signaling pathway ISO
Inferred from Sequence Orthology
more info
 
calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell morphogenesis ISO
Inferred from Sequence Orthology
more info
 
cellular calcium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
intestinal absorption IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
lactation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mammary gland branching involved in pregnancy IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organismal development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of keratinocyte proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
PubMed 
organ morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of apoptotic process involved in mammary gland involution IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
positive regulation of keratinocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
positive regulation of vitamin D 24-hydroxylase activity ISO
Inferred from Sequence Orthology
more info
 
regulation of calcidiol 1-monooxygenase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of calcium ion transport ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
skeletal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
steroid hormone mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
vitamin D receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
RNA polymerase II transcription factor complex ISO
Inferred from Sequence Orthology
more info
 
T-tubule ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with caveola ISO
Inferred from Sequence Orthology
more info
 
cell IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
dense fibrillar component ISO
Inferred from Sequence Orthology
more info
 
euchromatin ISO
Inferred from Sequence Orthology
more info
 
heterochromatin ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
nuclear heterochromatin ISO
Inferred from Sequence Orthology
more info
 
nuclear matrix ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
receptor complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
vitamin D3 receptor
Names
vitamin D3 receptor
1,25-dihydroxyvitamin D3 receptor
nuclear receptor subfamily 1 group I member 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009504.4NP_033530.2  vitamin D3 receptor

    See identical proteins and their annotated locations for NP_033530.2

    Status: VALIDATED

    Source sequence(s)
    AC158787, AK030339
    Consensus CDS
    CCDS27784.1
    UniProtKB/Swiss-Prot
    P48281
    Related
    ENSMUSP00000023119, OTTMUSP00000032572, ENSMUST00000023119, OTTMUST00000065367
    Conserved Domains (2) summary
    cd06933
    Location:124421
    NR_LBD_VDR; The ligand binding domain of vitamin D receptors, a member of the nuclear receptor superfamily
    cd06955
    Location:16122
    NR_DBD_VDR; DNA-binding domain of vitamin D receptors (VDR) is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    97854427..97908296
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    99981938..100035599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)