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    Serpini2 serine (or cysteine) peptidase inhibitor, clade I, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 67931, updated on 8-Aug-2016
    Official Symbol
    Serpini2provided by MGI
    Official Full Name
    serine (or cysteine) peptidase inhibitor, clade I, member 2provided by MGI
    Primary source
    MGI:MGI:1915181
    See related
    Ensembl:ENSMUSG00000034139 Vega:OTTMUSG00000026707
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spi14
    Orthologs
    Location:
    3; 3 E3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (75242357..75270078, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (75046293..75074000, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene zinc finger, B-box domain containing Neighboring gene predicted gene, 40071 Neighboring gene WD repeat domain 49 Neighboring gene keratin 8 pseudogene Neighboring gene programmed cell death 10

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    peptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    serine-type endopeptidase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    negative regulation of peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    serpin I2
    Names
    pancreas-specific serpin
    serine protease inhibitor 14

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026460.3NP_080736.2  serpin I2 precursor

      See identical proteins and their annotated locations for NP_080736.2

      Status: VALIDATED

      Source sequence(s)
      AC147152, AK007510, AK008931
      Consensus CDS
      CCDS17413.1
      UniProtKB/Swiss-Prot
      Q9JK88
      UniProtKB/TrEMBL
      Q4G0D3
      Related
      ENSMUSP00000046943, OTTMUSP00000033045, ENSMUST00000039047, OTTMUST00000066080
      Conserved Domains (1) summary
      cd02048
      Location:23405
      neuroserpin; Neuroserpin is a inhibitory member of the SERine Proteinase INhibitor (serpin) family that reacts preferentially with tissue-type plasminogen activator (tPA). It is located in neurons in regions of the brain where tPA is also found, suggesting that ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      75242357..75270078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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