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Gata1 GATA binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 14460, updated on 21-Feb-2015
Official Symbol
Gata1provided by MGI
Official Full Name
GATA binding protein 1provided by MGI
Primary source
MGI:MGI:95661
See related
Ensembl:ENSMUSG00000031162; Vega:OTTMUSG00000018011
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gf-1; eryf1; Gata-1
Orthologs
See Gata1 in MapViewer
Location:
X 3.59 cM; X A2
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (7959260..7976677, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene histone deacetylase 6 Neighboring gene uncharacterized LOC105243649 Neighboring gene proteasome (prosome, macropain) subunit, beta type 6, pseudogene Neighboring gene uncharacterized LOC105246623 Neighboring gene glyoxalase domain containing 5 Neighboring gene oxidative stress-responsive serine-rich protein 1 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
C2H2 zinc finger domain binding ISO
Inferred from Sequence Orthology
more info
 
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
DNA binding, bending IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II core promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
RNA polymerase II transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
chromatin DNA binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
enhancer sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
p53 binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
sequence-specific DNA binding RNA polymerase II transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
basophil differentiation IEA
Inferred from Electronic Annotation
more info
 
cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell-cell signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to thyroid hormone stimulus ISO
Inferred from Sequence Orthology
more info
 
dendritic cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
embryonic hemopoiesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
eosinophil differentiation IEA
Inferred from Electronic Annotation
more info
 
eosinophil fate commitment ISO
Inferred from Sequence Orthology
more info
 
erythrocyte development ISO
Inferred from Sequence Orthology
more info
 
erythrocyte differentiation IDA
Inferred from Direct Assay
more info
PubMed 
erythrocyte differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
erythrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
male gonad development ISO
Inferred from Sequence Orthology
more info
 
megakaryocyte differentiation IDA
Inferred from Direct Assay
more info
PubMed 
megakaryocyte differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
megakaryocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
megakaryocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
myeloid cell differentiation IMP
Inferred from Mutant Phenotype
more info
 
negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of bone mineralization IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
platelet aggregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
platelet aggregation ISO
Inferred from Sequence Orthology
more info
 
platelet formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
platelet formation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of osteoblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of peptidyl-tyrosine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
regulation of definitive erythrocyte differentiation IDA
Inferred from Direct Assay
more info
PubMed 
regulation of definitive erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of glycoprotein biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of glycoprotein biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcriptional activation by promoter-enhancer looping IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
transcription factor complex ISO
Inferred from Sequence Orthology
more info
 
transcriptional repressor complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
erythroid transcription factor
Names
erythroid transcription factor
GATA-binding factor 1
GATA-binding protein 1
NF-E1 DNA-binding protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008089.2NP_032115.1  erythroid transcription factor

    See proteins identical to NP_032115.1

    Status: VALIDATED

    Source sequence(s)
    AL670169, X15763
    Consensus CDS
    CCDS29981.1
    UniProtKB/Swiss-Prot
    P17679
    Related
    ENSMUSP00000033502, OTTMUSP00000019548, ENSMUST00000033502, OTTMUST00000043496
    Conserved Domains (1) summary
    cd00202
    Location:203249
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    7959260..7976677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247448.1XP_011245750.1  

    See proteins identical to XP_011245750.1

    Conserved Domains (1) summary
    cd00202
    Location:203249
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    3501658..3509992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)