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    Cam Calmodulin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36329, updated on 5-Jul-2015
    Official Symbol
    Camprovided by FlyBase
    Official Full Name
    Calmodulinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000253
    Locus tag
    Dmel_CG8472
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    3909; anon-EST:Posey59; Cal; Cal49A; cam; CaM; CAM; Cam1; CG8472; D-CaM; dCaM; DmCalm; DmCaM; Dmel\CG8472; l(2)03909; l(2)3909; lincRNA.S2634
    Location:
    48F1-48F1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.01 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12259398..12278809)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8146903..8166314)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene CG13168 gene product from transcript CG13168-RC Neighboring gene Vacuolar H[+] ATPase 36kD subunit 2 Neighboring gene ncRNA Neighboring gene CG42700 gene product from transcript CG42700-RJ Neighboring gene ncRNA Neighboring gene CG8850 gene product from transcript CG8850-RB

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    calcium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium ion binding NAS
    Non-traceable Author Statement
    more info
     
    myosin V binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    myosin VI head/neck binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    myosin heavy chain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    actin filament-based movement IDA
    Inferred from Direct Assay
    more info
    PubMed 
    adaptation of rhodopsin mediated signaling TAS
    Traceable Author Statement
    more info
    PubMed 
    centriole replication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    deactivation of rhodopsin mediated signaling TAS
    Traceable Author Statement
    more info
    PubMed 
    detection of calcium ion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    kinetochore organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lateral inhibition IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    metarhodopsin inactivation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    mitotic spindle assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    muscle cell cellular homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    photoreceptor cell axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of NFAT protein import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cation channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of light-activated channel activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of response to DNA damage stimulus IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    rhabdomere development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    rhodopsin mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    salivary gland cell autophagic cell death IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sensory perception of smell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sensory perception of sound IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    centriole IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule associated complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    midbody IDA
    Inferred from Direct Assay
    more info
    PubMed 
    myosin V complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    myosin VI complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    rhabdomere IDA
    Inferred from Direct Assay
    more info
    PubMed 
    rhabdomere TAS
    Traceable Author Statement
    more info
    PubMed 
    spindle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    spindle pole IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with spindle pole IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    CG8472 gene product from transcript CG8472-RC
    Names
    CG8472-PA
    CG8472-PB
    CG8472-PC
    CG8472-PD
    CG8472-PE
    Cam-PA
    Cam-PB
    Cam-PC
    Cam-PD
    Cam-PE
    calmodulin

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12259398..12278809
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259347.2NP_001246276.1  calmodulin, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246276.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LF57
      UniProtKB/Swiss-Prot
      P62152
      Related
      FBpp0293502, FBtr0304963
      Conserved Domains (2) summary
      PTZ00184
      Location:1149
      PTZ00184; calmodulin; Provisional
      cd00051
      Location:85147
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    2. NM_078986.3NP_523710.1  calmodulin, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523710.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LF57
      UniProtKB/Swiss-Prot
      P62152
      Related
      FBpp0087109, FBtr0088001
      Conserved Domains (2) summary
      PTZ00184
      Location:1149
      PTZ00184; calmodulin; Provisional
      cd00051
      Location:85147
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    3. NM_001299408.1NP_001286337.1  calmodulin, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286337.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LF57
      UniProtKB/Swiss-Prot
      P62152
      Related
      FBpp0311269, FBtr0345018
      Conserved Domains (2) summary
      PTZ00184
      Location:1149
      PTZ00184; calmodulin; Provisional
      cd00051
      Location:85147
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    4. NM_001259348.3NP_001246277.1  calmodulin, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246277.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LF57
      UniProtKB/Swiss-Prot
      P62152
      Related
      FBpp0293503, FBtr0304964
      Conserved Domains (2) summary
      PTZ00184
      Location:1149
      PTZ00184; calmodulin; Provisional
      cd00051
      Location:85147
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    5. NM_165870.2NP_725120.1  calmodulin, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725120.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LF57
      UniProtKB/Swiss-Prot
      P62152
      Related
      FBpp0087110, FBtr0088002
      Conserved Domains (2) summary
      PTZ00184
      Location:1149
      PTZ00184; calmodulin; Provisional
      cd00051
      Location:85147
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...