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    Adh1 alcohol dehydrogenase 1 (class I) [ Mus musculus (house mouse) ]

    Gene ID: 11522, updated on 23-Apr-2016
    Official Symbol
    Adh1provided by MGI
    Official Full Name
    alcohol dehydrogenase 1 (class I)provided by MGI
    Primary source
    MGI:MGI:87921
    See related
    Ensembl:ENSMUSG00000074207 Vega:OTTMUSG00000034747
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Adh-1; ADH-AA; Adh-1e; Adh-1t; Adh-3e; Adh1-e; Adh1-t; Adh1tl; Adh3-e; Adh-1-t; AI194826
    Orthologs
    Location:
    3 G3; 3 64.16 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (138277645..138290691)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (137940609..137953655)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 0610031O16 gene Neighboring gene alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide Neighboring gene predicted gene, 40156 Neighboring gene predicted gene 16559 Neighboring gene alcohol dehydrogenase 6A (class V)

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NAD binding ISO
    Inferred from Sequence Orthology
    more info
     
    alcohol dehydrogenase (NAD) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    alcohol dehydrogenase (NAD) activity ISO
    Inferred from Sequence Orthology
    more info
     
    alcohol dehydrogenase (NAD) activity TAS
    Traceable Author Statement
    more info
    PubMed 
    alcohol dehydrogenase activity, zinc-dependent ISO
    Inferred from Sequence Orthology
    more info
     
    drug binding ISO
    Inferred from Sequence Orthology
    more info
     
    ethanol binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    retinol dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acetaldehyde biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    behavioral response to ethanol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ethanol catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ethanol catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ethanol oxidation ISO
    Inferred from Sequence Orthology
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    response to retinoic acid IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to steroid hormone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to testosterone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    retinoic acid metabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    retinoic acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    retinoid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    retinol metabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    retinol metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    alcohol dehydrogenase 1
    Names
    ADH-A2
    alcohol dehydrogenase 1 temporal, liver
    alcohol dehydrogenase 1, complex
    alcohol dehydrogenase 1, electrophoretic
    alcohol dehydrogenase 3, electrophoretic
    alcohol dehydrogenase A subunit
    class I alcohol dehydrogenase
    NP_031435.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007409.2NP_031435.1  alcohol dehydrogenase 1

      See identical proteins and their annotated locations for NP_031435.1

      Status: PROVISIONAL

      Source sequence(s)
      BC013477
      Consensus CDS
      CCDS17867.1
      UniProtKB/Swiss-Prot
      P00329
      UniProtKB/TrEMBL
      Q3UKA4
      Related
      ENSMUSP00000004232, OTTMUSP00000048109, ENSMUST00000004232, OTTMUST00000088306
      Conserved Domains (2) summary
      cd08299
      Location:3375
      alcohol_DH_class_I_II_IV; class I, II, IV alcohol dehydrogenases
      COG1062
      Location:8375
      FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

      Range
      138277645..138290691
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000025.1 Alternate Mm_Celera

      Range
      144684702..144697775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)