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    tonB membrane spanning protein in TonB-ExbB-ExbD transport complex [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945843, updated on 25-Jul-2015
    Gene symbol
    tonB
    Gene description
    membrane spanning protein in TonB-ExbB-ExbD transport complex
    Primary source
    EcoGene:EG11012
    Locus tag
    b1252
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1246; exbA; JW5195; T1rec
    Summary
    Periplasmic TonB is attached to the cytoplasmic membrane by a signal anchor and interacts with outer membrane proteins, thus TonB spans the periplasmic space. [More information is available at EcoGene: EG11012]. TonB is a cytoplasmic membrane protein which transduces the proton motive force (pmf) of the cytoplasmic membrane to the outer membrane active transporters thus providing the energy source required for the import of iron-siderophore complexes and vitamin B12 across the outer membrane . [More information is available at EcoCyc: EG11012].
    Sequence:
    NC_000913.3 (1311089..1311808)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene voltage-gated potassium channel Neighboring gene putative DGPF domain-containing enzyme Neighboring gene acyl-CoA esterase Neighboring gene IspA family inner membrane protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description
    Names
    membrane spanning protein in TonB-ExbB-ExbD transport complex
    NP_415768.1
    • energy transducer; uptake of iron, cyanocobalimin; sensitivity to phages, colicins

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1311089..1311808
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415768.1 membrane spanning protein in TonB-ExbB-ExbD transport complex [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415768.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P02929
      Conserved Domains (2) summary
      PRK10819
      Location:1239
      PRK10819; transport protein TonB; Provisional
      pfam03544
      Location:160232
      TonB_C; Gram-negative bacterial TonB protein C-terminal