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Rgs9 regulator of G-protein signaling 9 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29481, updated on 27-Jan-2015
Official Symbol
Rgs9provided by RGD
Official Full Name
regulator of G-protein signaling 9provided by RGD
Primary source
RGD:3572
See related
Ensembl:ENSRNOG00000003800
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
splice variant Rgs9l may act as a GTPase activating protein; inhibits dopamine D2 receptor induced G protein-coupled inward rectifier K+ channel current [RGD, Feb 2006]
Annotation information
Annotation category: suggests misassembly
Orthologs
See Rgs9 in MapViewer
Location:
10q32.1
Exon count:
19
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (97509971..97582188, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (97225541..97298645, complement)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene hypothetical protein LOC689085 Neighboring gene similar to ribosomal protein L10a Neighboring gene uncharacterized LOC102550782 Neighboring gene uncharacterized LOC102550846 Neighboring gene guanine nucleotide binding protein (G protein), alpha 13

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
GTPase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
protein complex binding IDA
Inferred from Direct Assay
more info
PubMed 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
dopamine receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
nervous system development IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
regulation of G-protein coupled receptor protein signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
response to estrogen IEP
Inferred from Expression Pattern
more info
PubMed 
termination of G-protein coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
visual perception IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
heterotrimeric G-protein complex IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
photoreceptor inner segment ISO
Inferred from Sequence Orthology
more info
 
photoreceptor outer segment ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
regulator of G-protein signaling 9
Names
regulator of G-protein signaling 9

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019224.2NP_062097.1  regulator of G-protein signaling 9

    See proteins identical to NP_062097.1

    Status: PROVISIONAL

    Source sequence(s)
    AB019145
    UniProtKB/Swiss-Prot
    P49805
    Related
    ENSRNOP00000005076, ENSRNOT00000005076
    Conserved Domains (3) summary
    cd08739
    Location:292412
    RGS_RGS9; Regulator of G protein signaling (RGS) domain found in the RGS9 protein
    cd00068
    Location:219274
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors
    cd04450
    Location:22109
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    97509971..97582188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    92858619..92931658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)