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Pkd1 polycystic kidney disease 1 homolog [ Mus musculus (house mouse) ]

Gene ID: 18763, updated on 1-Mar-2015
Official Symbol
Pkd1provided by MGI
Official Full Name
polycystic kidney disease 1 homologprovided by MGI
Primary source
MGI:MGI:97603
See related
Ensembl:ENSMUSG00000032855
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PC1; mFLJ00285
Orthologs
See Pkd1 in MapViewer
Location:
17 A3.3; 17 12.4 cM
Exon count:
47
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 17 NC_000083.6 (24549950..24596514)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene RAB26, member RAS oncogene family Neighboring gene predicted gene, 33508 Neighboring gene tuberous sclerosis 2 Neighboring gene nth (endonuclease III)-like 1 (E.coli) Neighboring gene solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ00285, MGC118471

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium channel activity TAS
Traceable Author Statement
more info
PubMed 
carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
cation channel activity IPI
Inferred from Physical Interaction
more info
PubMed 
ion channel binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
JAK-STAT cascade IDA
Inferred from Direct Assay
more info
PubMed 
blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
branching morphogenesis of an epithelial tube IDA
Inferred from Direct Assay
more info
PubMed 
branching morphogenesis of an epithelial tube ISO
Inferred from Sequence Orthology
more info
 
calcium ion transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion transmembrane transport TAS
Traceable Author Statement
more info
PubMed 
calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
cartilage condensation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cation transmembrane transport IPI
Inferred from Physical Interaction
more info
PubMed 
cell cycle arrest IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic sequestering of transcription factor IMP
Inferred from Mutant Phenotype
more info
PubMed 
detection of mechanical stimulus IDA
Inferred from Direct Assay
more info
PubMed 
detection of mechanical stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryonic placenta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of cell polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
in utero embryonic development IGI
Inferred from Genetic Interaction
more info
PubMed 
in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
kidney development IGI
Inferred from Genetic Interaction
more info
PubMed 
kidney development IMP
Inferred from Mutant Phenotype
more info
PubMed 
liver development IGI
Inferred from Genetic Interaction
more info
PubMed 
lymph vessel morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
nitrogen compound metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
patterning of lymph vessels ISO
Inferred from Sequence Orthology
more info
 
peptidyl-serine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
placenta blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
protein export from nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mitotic spindle organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of proteasomal protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of proteasomal protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
renal system development IGI
Inferred from Genetic Interaction
more info
PubMed 
response to fluid shear stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
single organismal cell-cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cilium IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
lateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
motile primary cilium IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IPI
Inferred from Physical Interaction
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
polycystin complex IDA
Inferred from Direct Assay
more info
PubMed 
primary cilium IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
polycystin-1
Names
polycystin-1
autosomal dominant polycystic kidney disease 1 protein homolog
polycystic kidney disease 1 homolog; polycystin-1
polycystin 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013630.2NP_038658.2  polycystin-1 precursor

    See proteins identical to NP_038658.2

    Status: VALIDATED

    Source sequence(s)
    AC132367, AK147429, AK220312, BB805513, U70209
    Consensus CDS
    CCDS28485.1
    UniProtKB/Swiss-Prot
    O08852
    UniProtKB/TrEMBL
    Q5DU58
    Related
    ENSMUSP00000049296, ENSMUST00000035565
    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972723
    PCC; polycystin cation channel protein
    smart00303
    Location:30033052
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19682054
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12111287
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31103229
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18881957
    PKD; PKD domain
    pfam08016
    Location:37014103
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p3 C57BL/6J

    Range
    24549950..24596514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523834.1XP_006523897.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972731
    PCC; polycystin cation channel protein
    smart00303
    Location:30113060
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31183237
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:37244126
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  2. XM_006523841.2XP_006523904.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972731
    PCC; polycystin cation channel protein
    smart00303
    Location:30113060
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31183237
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:37104112
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  3. XM_006523835.1XP_006523898.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972731
    PCC; polycystin cation channel protein
    smart00303
    Location:30113060
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31183237
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:37234125
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  4. XM_006523842.2XP_006523905.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972731
    PCC; polycystin cation channel protein
    smart00303
    Location:30113060
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31183237
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:37094111
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  5. XM_006523849.1XP_006523912.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972731
    PCC; polycystin cation channel protein
    smart00303
    Location:30113060
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31183237
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:36864088
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  6. XM_006523851.2XP_006523914.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972731
    PCC; polycystin cation channel protein
    smart00303
    Location:30113060
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31183237
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:36724074
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  7. XM_006523850.1XP_006523913.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972731
    PCC; polycystin cation channel protein
    smart00303
    Location:30113060
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31183237
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:36854087
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  8. XM_006523852.2XP_006523915.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972731
    PCC; polycystin cation channel protein
    smart00303
    Location:30113060
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31183237
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:36714073
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  9. XM_006523837.2XP_006523900.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972729
    PCC; polycystin cation channel protein
    smart00303
    Location:30093058
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19682054
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12111287
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31163235
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18881957
    PKD; PKD domain
    pfam08016
    Location:37224124
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  10. XM_006523836.1XP_006523899.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972730
    PCC; polycystin cation channel protein
    smart00303
    Location:30103059
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19692055
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12121288
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31173236
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18891958
    PKD; PKD domain
    pfam08016
    Location:37234125
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  11. XM_006523838.2XP_006523901.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972728
    PCC; polycystin cation channel protein
    smart00303
    Location:30083057
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19672053
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12101286
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31153234
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18871956
    PKD; PKD domain
    pfam08016
    Location:37214123
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  12. XM_006523848.1XP_006523911.1  

    Conserved Domains (12) summary
    cd00037
    Location:394506
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:732707
    PCC; polycystin cation channel protein
    smart00303
    Location:29873036
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:101153
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19462032
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:153247
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:11891265
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:30943213
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18661935
    PKD; PKD domain
    pfam08016
    Location:37004102
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:72104
    LRR_4; Leucine Rich repeats (2 copies)
  13. XM_006523839.1XP_006523902.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972725
    PCC; polycystin cation channel protein
    smart00303
    Location:30053054
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31123231
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:37184120
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  14. XM_006523843.1XP_006523906.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972725
    PCC; polycystin cation channel protein
    smart00303
    Location:30053054
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31123231
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:37044106
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  15. XM_006523844.1XP_006523907.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972725
    PCC; polycystin cation channel protein
    smart00303
    Location:30053054
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19702056
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12131289
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31123231
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18901959
    PKD; PKD domain
    pfam08016
    Location:37034105
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  16. XM_006523845.1XP_006523908.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972723
    PCC; polycystin cation channel protein
    smart00303
    Location:30033052
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19682054
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12111287
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31103229
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18881957
    PKD; PKD domain
    pfam08016
    Location:37024104
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  17. XM_006523840.1XP_006523903.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972722
    PCC; polycystin cation channel protein
    smart00303
    Location:30023051
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19672053
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12101286
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31093228
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18871956
    PKD; PKD domain
    pfam08016
    Location:37154117
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  18. XM_006523846.1XP_006523909.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972722
    PCC; polycystin cation channel protein
    smart00303
    Location:30023051
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19672053
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12101286
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31093228
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18871956
    PKD; PKD domain
    pfam08016
    Location:37014103
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  19. XM_006523847.1XP_006523910.1  

    Conserved Domains (13) summary
    cd00037
    Location:418530
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    TIGR00864
    Location:972722
    PCC; polycystin cation channel protein
    smart00303
    Location:30023051
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00013
    Location:3271
    LRRNT; Leucine rich repeat N-terminal domain
    smart00082
    Location:125177
    LRRCT; Leucine rich repeat C-terminal domain
    smart00089
    Location:19672053
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    smart00321
    Location:177271
    WSC; present in yeast cell wall integrity and stress response component proteins
    cd00146
    Location:12101286
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:31093228
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:18871956
    PKD; PKD domain
    pfam08016
    Location:37004102
    PKD_channel; Polycystin cation channel
    pfam12799
    Location:93128
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:61127
    LRR_8; Leucine rich repeat
  20. XM_006523853.1XP_006523916.1  

    Conserved Domains (8) summary
    smart00303
    Location:20002049
    GPS; G-protein-coupled receptor proteolytic site domain
    smart00089
    Location:9591045
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    COG3291
    Location:144341
    COG3291; FOG: PKD repeat [General function prediction only]
    cd00146
    Location:202278
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...
    cd01752
    Location:21072226
    PLAT_polycystin; PLAT/LH2 domain of polycystin-1 like proteins. Polycystins are a large family of membrane proteins composed of multiple domains, present in fish, invertebrates, mammals, and humans that are widely expressed in various cell types and whose biological ...
    pfam00801
    Location:879948
    PKD; PKD domain
    pfam02010
    Location:11581607
    REJ; REJ domain
    pfam08016
    Location:27133115
    PKD_channel; Polycystin cation channel

Alternate Mm_Celera

Genomic

  1. AC_000039.1 Alternate Mm_Celera

    Range
    25067435..25114509
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)