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    RAG2 recombination activating gene 2 [ Gallus gallus (chicken) ]

    Gene ID: 423165, updated on 8-Aug-2016
    Official Symbol
    RAG2provided by CGNC
    Official Full Name
    recombination activating gene 2provided by CGNC
    Primary source
    CGNC:6005
    See related
    Ensembl:ENSGALG00000007940
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    Rag-2
    Orthologs
    Location:
    chromosome: 5
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    103 current Gallus_gallus-5.0 (GCF_000002315.4) 5 NC_006092.4 (19519715..19524759, complement)
    102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 5 NC_006092.3 (18811456..18830468, complement)

    Chromosome 5 - NC_006092.4Genomic Context describing neighboring genes Neighboring gene chromosome 5 open reading frame, human C11orf74 Neighboring gene TNF receptor associated factor 6 Neighboring gene recombination activating gene 1 Neighboring gene uncharacterized LOC101752331 Neighboring gene uncharacterized LOC107053456

    • FoxO signaling pathway, organism-specific biosystem (from KEGG)
      FoxO signaling pathway, organism-specific biosystemThe forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellular physiological events including apoptosis, cell-cycle control, glucose metabolism, oxidative str...

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    methylated histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phosphatidylinositol binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phosphatidylinositol-3,4,5-trisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phosphatidylinositol-3,4-bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phosphatidylinositol-3,5-bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phosphatidylinositol-4,5-bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    B cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    B cell homeostatic proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    B cell lineage commitment IEA
    Inferred from Electronic Annotation
    more info
     
    T cell differentiation in thymus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    T cell lineage commitment IEA
    Inferred from Electronic Annotation
    more info
     
    V(D)J recombination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    covalent chromatin modification IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of organ growth IEA
    Inferred from Electronic Annotation
    more info
     
    pre-B cell allelic exclusion IEA
    Inferred from Electronic Annotation
    more info
     
    protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    V(D)J recombination-activating protein 2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305057.2NP_001291986.1  V(D)J recombination-activating protein 2

      See identical proteins and their annotated locations for NP_001291986.1

      Status: VALIDATED

      Source sequence(s)
      AADN04000062, CV889695
      Conserved Domains (4) summary
      pfam03089
      Location:58398
      RAG2; Recombination activating protein 2
      pfam13415
      Location:95152
      Kelch_3; Galactose oxidase, central domain
      sd00038
      Location:144208
      Kelch; KELCH repeat [structural motif]
      cd15569
      Location:423489
      PHD_RAG2; PHD finger found in V(D)J recombination-activating protein 2 (RAG-2) and similar proteins

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 103 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Gallus_gallus-5.0 Primary Assembly

    Genomic

    1. NC_006092.4 Reference Gallus_gallus-5.0 Primary Assembly

      Range
      19519715..19524759 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)