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Col5a2 collagen, type V, alpha 2 [ Mus musculus (house mouse) ]

Gene ID: 12832, updated on 19-Jul-2014
Official Symbol
Col5a2provided by MGI
Official Full Name
collagen, type V, alpha 2provided by MGI
Primary source
MGI:88458
See related
Ensembl:ENSMUSG00000026042; Vega:OTTMUSG00000021356
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D230017N05; 1110014L14Rik
See Col5a2 in Epigenomics, MapViewer
Location:
1 C1; 1
Exon count:
54
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 1 NC_000067.6 (45374331..45503282, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene heat shock protein 1 (chaperonin) pseudogene 12 Neighboring gene collagen, type III, alpha 1 Neighboring gene chromobox protein homolog 3 pseudogene Neighboring gene apurinic/apyrimidinic endonuclease 1 pseudogene

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  • Amoebiasis, organism-specific biosystem (from KEGG)
    Amoebiasis, organism-specific biosystemEntamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis o...
  • Amoebiasis, conserved biosystem (from KEGG)
    Amoebiasis, conserved biosystemEntamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis o...
  • ECM-receptor interaction, organism-specific biosystem (from KEGG)
    ECM-receptor interaction, organism-specific biosystemThe extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell ...
  • ECM-receptor interaction, conserved biosystem (from KEGG)
    ECM-receptor interaction, conserved biosystemThe extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell ...
  • Focal Adhesion, organism-specific biosystem (from WikiPathways)
    Focal Adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Focal adhesion, organism-specific biosystem (from KEGG)
    Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Focal adhesion, conserved biosystem (from KEGG)
    Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
    PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
    PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • Platelet activation, organism-specific biosystem (from KEGG)
    Platelet activation, organism-specific biosystemPlatelets play a key and beneficial role for primary hemostasis on the disruption of the integrity of vessel wall. Platelet adhesion and activation at sites of vascular wall injury is initiated by ad...
  • Protein digestion and absorption, organism-specific biosystem (from KEGG)
    Protein digestion and absorption, organism-specific biosystemProtein is a dietary component essential for nutritional homeostasis in humans. Normally, ingested protein undergoes a complex series of degradative processes following the action of gastric, pancrea...
  • Protein digestion and absorption, conserved biosystem (from KEGG)
    Protein digestion and absorption, conserved biosystemProtein is a dietary component essential for nutritional homeostasis in humans. Normally, ingested protein undergoes a complex series of degradative processes following the action of gastric, pancrea...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
SMAD binding IPI
Inferred from Physical Interaction
more info
PubMed 
extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cellular response to amino acid stimulus IDA
Inferred from Direct Assay
more info
 
collagen fibril organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
collagen fibril organization ISO
Inferred from Sequence Orthology
more info
 
eye morphogenesis ISO
Inferred from Sequence Orthology
more info
 
skeletal system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
skin development IMP
Inferred from Mutant Phenotype
more info
PubMed 
skin development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
collagen trimer IDA
Inferred from Direct Assay
more info
PubMed 
collagen type V trimer ISO
Inferred from Sequence Orthology
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
proteinaceous extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
collagen alpha-2(V) chain
Names
collagen alpha-2(V) chain
procollagen, type V, alpha 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007737.2NP_031763.2  collagen alpha-2(V) chain precursor

    See proteins identical to NP_031763.2

    Status: VALIDATED

    Source sequence(s)
    AK003709, AK132413, AK139130, AK147328
    Consensus CDS
    CCDS35555.1
    UniProtKB/Swiss-Prot
    Q3U962
    Related
    ENSMUSP00000083620, OTTMUSP00000023677, ENSMUST00000086430, OTTMUST00000050640
    Conserved Domains (3) summary
    pfam01391
    Location:493551
    Blast Score: 119
    Collagen; Collagen triple helix repeat (20 copies)
    smart00038
    Location:12631497
    Blast Score: 1066
    COLFI; Fibrillar collagens C-terminal domain
    smart00214
    Location:4095
    Blast Score: 228
    VWC; von Willebrand factor (vWF) type C domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000067.6 

    Range
    45374331..45503282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000023.1 

    Range
    45675438..45811971
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)