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Jra Jun-related antigen [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36057, updated on 7-Sep-2014
Official Symbol
Jraprovided by FlyBase
Official Full Name
Jun-related antigenprovided by FlyBase
Primary source
FLYBASE:FBgn0001291
Locus tag
Dmel_CG2275
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AP-1; AP1; c-Jun; CG2275; cJun; d-JRA; d-jun; d-Jun; D-jun; D-Jun; D-jun/Jra; dAP-1; dJra; dJRA; djun; dJun; dJUN; Djun; DJun; DJUN; dm-Jun; Dmel\CG2275; jra; JRA; jun; Jun; JUN; l(2)46Ef; l(2)IA109; l(2R)IA109; V
Location:
46E4-46E5; 2-60 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.01 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10096480..10098556)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5983985..5986061)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene small Cajal body-specific RNA : MeU1b-A234 Neighboring gene eiger Neighboring gene CG2269 gene product from transcript CG2269-RD Neighboring gene sugar transporter 4 Neighboring gene Ribosomal protein LP0-like Neighboring gene CG17870 gene product from transcript CG17870-RE Neighboring gene Phosphofructokinase

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding RNA polymerase II transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
sequence-specific DNA binding transcription factor activity NAS
Non-traceable Author Statement
more info
 
transcription factor binding NAS
Non-traceable Author Statement
more info
 
transcription factor binding TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
JNK cascade IGI
Inferred from Genetic Interaction
more info
PubMed 
JNK cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
JNK cascade TAS
Traceable Author Statement
more info
PubMed 
MAPK cascade TAS
Traceable Author Statement
more info
PubMed 
R3/R4 cell fate commitment TAS
Traceable Author Statement
more info
PubMed 
R7 cell fate commitment TAS
Traceable Author Statement
more info
PubMed 
dorsal appendage formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal closure IGI
Inferred from Genetic Interaction
more info
PubMed 
dorsal closure IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal closure NAS
Non-traceable Author Statement
more info
PubMed 
dorsal closure TAS
Traceable Author Statement
more info
PubMed 
establishment of planar polarity NAS
Non-traceable Author Statement
more info
PubMed 
imaginal disc fusion, thorax closure IMP
Inferred from Mutant Phenotype
more info
PubMed 
micropyle formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organismal aging IMP
Inferred from Mutant Phenotype
more info
 
negative regulation of antimicrobial humoral response IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of antimicrobial humoral response IMP
Inferred from Mutant Phenotype
more info
PubMed 
phagocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of heart contraction IMP
Inferred from Mutant Phenotype
more info
 
positive regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription from RNA polymerase II promoter NAS
Non-traceable Author Statement
more info
 
synaptic growth at neuromuscular junction IGI
Inferred from Genetic Interaction
more info
PubMed 
wound healing IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with cytoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with nucleus IDA
Inferred from Direct Assay
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus NAS
Non-traceable Author Statement
more info
 
transcription factor complex IPI
Inferred from Physical Interaction
more info
PubMed 
Preferred Names
CG2275 gene product from transcript CG2275-RB
Names
CG2275-PA
CG2275-PB
CG2275-PC
Jra-PA
Jra-PB
Jra-PC
Jun oncogene
Jun related antigen
Jun-related antigen
activator protein 1
complementation group V
lethal(2)1A109
lethal(2)IA109

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 

    Range
    10096480..10098556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165739.2NP_724882.1  Jun-related antigen, isoform B [Drosophila melanogaster]

    See proteins identical to NP_724882.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P18289
    Related
    FBpp0087498, FBtr0088410
    Conserved Domains (2) summary
    cd12193
    Location:213266
    Blast Score: 186
    B_zip1; basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins
    pfam03957
    Location:1204
    Blast Score: 376
    Jun; Jun-like transcription factor
  2. NM_057238.5NP_476586.1  Jun-related antigen, isoform A [Drosophila melanogaster]

    See proteins identical to NP_476586.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P18289
    Related
    FBpp0087499, FBtr0088411
    Conserved Domains (2) summary
    cd12193
    Location:213266
    Blast Score: 186
    B_zip1; basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins
    pfam03957
    Location:1204
    Blast Score: 376
    Jun; Jun-like transcription factor
  3. NM_001273915.2NP_001260844.1  Jun-related antigen, isoform C [Drosophila melanogaster]

    See proteins identical to NP_001260844.1

    Status: REVIEWED

    Related
    FBpp0303456, FBtr0330606
    Conserved Domains (2) summary
    cd12193
    Location:213266
    Blast Score: 180
    B_zip1; basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins
    pfam03957
    Location:1204
    Blast Score: 366
    Jun; Jun-like transcription factor