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Bcl11a B cell CLL/lymphoma 11A (zinc finger protein) [ Mus musculus (house mouse) ]

Gene ID: 14025, updated on 9-Jul-2014
Official Symbol
Bcl11aprovided by MGI
Official Full Name
B cell CLL/lymphoma 11A (zinc finger protein)provided by MGI
Primary source
MGI:106190
Locus tag
RP23-365O24.1
See related
Ensembl:ENSMUSG00000000861; Vega:OTTMUSG00000005291
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Evi9; Ctip1; Evi9a; Evi9b; Evi9c; BCL-11A; mKIAA1809; 2810047E18Rik; D930021L15Rik
See Bcl11a in Epigenomics, MapViewer
Location:
11 A3.2; 11
Exon count :
10
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 11 NC_000077.6 (24076564..24173558)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene poly(A) polymerase gamma Neighboring gene uncharacterized LOC102636054 Neighboring gene uncharacterized LOC102636133 Neighboring gene uncharacterized LOC102636347 Neighboring gene uncharacterized LOC102636265

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
B cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
T cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of collateral sprouting ISO
Inferred from Sequence Orthology
more info
 
negative regulation of dendrite development ISO
Inferred from Sequence Orthology
more info
 
negative regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
positive regulation of collateral sprouting ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
protein sumoylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of RNA biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
regulation of dendrite development ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nuclear body IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
B-cell lymphoma/leukemia 11A
Names
B-cell lymphoma/leukemia 11A
EVI-9
myeloid leukemia
COUP-TF interacting protein 1
COUP-TF-interacting protein 1
ecotropic viral integration site 9 protein
B-cell CLL/lymphoma 11A (zinc finger protein)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159289.1NP_001152761.1  B-cell lymphoma/leukemia 11A isoform 2

    See proteins identical to NP_001152761.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different splice site in the 3' coding region, compared to variant 4. The resulting protein (isoform 2) has a shorter C-terminus when it is compared to isoform 4.
    Source sequence(s)
    AA008362, AK004395, AK045556, BB853515, BY735002
    Consensus CDS
    CCDS48758.1
    UniProtKB/Swiss-Prot
    Q9QYE3
  2. NM_001159290.1NP_001152762.1  B-cell lymphoma/leukemia 11A isoform 3

    See proteins identical to NP_001152762.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has multiple differences, one of which results in the use of a downstream start codon, compared to variant 4. The resulting protein (isoform 3) is shorter when it is compared to isoform 4.
    Source sequence(s)
    AK045556
    Consensus CDS
    CCDS48759.1
    UniProtKB/Swiss-Prot
    Q9QYE3
    Related
    ENSMUSP00000112948, OTTMUSP00000005475, ENSMUST00000118955, OTTMUST00000011801
  3. NM_001242934.1NP_001229863.1  B-cell lymphoma/leukemia 11A isoform 4

    See proteins identical to NP_001229863.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) represents the longest transcript and encodes the longest protein (isoform 4).
    Source sequence(s)
    AK045556, AK140949, AK164574, BB649527, BB662872, BF731393, BY735002, CB524780, CD355476
    Consensus CDS
    CCDS56764.1
    UniProtKB/TrEMBL
    Q3TP99
    UniProtKB/TrEMBL
    Q3US10
    UniProtKB/TrEMBL
    Q5STS9
    UniProtKB/Swiss-Prot
    Q9QYE3
    Related
    ENSMUSP00000105140, OTTMUSP00000005479, ENSMUST00000109514, OTTMUST00000011806
    Conserved Domains (2) summary
    pfam00096
    Location:743764
    Blast Score: 82
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:756781
    Blast Score: 97
    zf-H2C2_2; Zinc-finger double domain
  4. NM_016707.3NP_057916.1  B-cell lymphoma/leukemia 11A isoform 1

    See proteins identical to NP_057916.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses a different splice site in the 3' coding region, compared to variant 4. The resulting protein (isoform 1) has a shorter C-terminus when it is compared to isoform 4.
    Source sequence(s)
    AF169037, AL672018, BB649527, BY735002
    Consensus CDS
    CCDS24483.1
    UniProtKB/Swiss-Prot
    Q9QYE3
    Related
    ENSMUSP00000000881, OTTMUSP00000005476, ENSMUST00000000881, OTTMUST00000011803
    Conserved Domains (2) summary
    pfam00096
    Location:378399
    Blast Score: 81
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:391416
    Blast Score: 98
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000077.6 

    Range
    24076564..24173558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006514504.1XP_006514567.1  

    See proteins identical to XP_006514567.1

    UniProtKB/TrEMBL
    Q5STS9
    Conserved Domains (2) summary
    pfam00096
    Location:743764
    Blast Score: 82
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:756781
    Blast Score: 97
    zf-H2C2_2; Zinc-finger double domain
  2. XM_006514506.1XP_006514569.1  

    See proteins identical to XP_006514569.1

    UniProtKB/TrEMBL
    Q5STS9
    Conserved Domains (2) summary
    pfam00096
    Location:743764
    Blast Score: 82
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:756781
    Blast Score: 97
    zf-H2C2_2; Zinc-finger double domain
  3. XM_006514505.1XP_006514568.1  

    See proteins identical to XP_006514568.1

    UniProtKB/TrEMBL
    Q5STS9
    Conserved Domains (2) summary
    pfam00096
    Location:743764
    Blast Score: 82
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:756781
    Blast Score: 97
    zf-H2C2_2; Zinc-finger double domain
  4. XM_006514507.1XP_006514570.1  

    Conserved Domains (2) summary
    pfam00096
    Location:691712
    Blast Score: 82
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:704729
    Blast Score: 97
    zf-H2C2_2; Zinc-finger double domain

Alternate Mm_Celera

Genomic

  1. AC_000033.1 

    Range
    26200322..26297352
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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