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Opn4 opsin 4 (melanopsin) [ Mus musculus (house mouse) ]

Gene ID: 30044, updated on 26-Aug-2014
Official Symbol
Opn4provided by MGI
Official Full Name
opsin 4 (melanopsin)provided by MGI
Primary source
MGI:1353425
See related
Ensembl:ENSMUSG00000021799
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm533; 1110007J02Rik
See Opn4 in Epigenomics, MapViewer
Location:
14 B; 14
Exon count:
10
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 14 NC_000080.6 (34590618..34600142, complement)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9230112D13 gene Neighboring gene 60S ribosomal protein L21-like Neighboring gene LIM domain binding 3 Neighboring gene wings apart-like homolog (Drosophila) Neighboring gene RIKEN cDNA A930038B10 gene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
11-cis retinal binding ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled photoreceptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G-protein coupled photoreceptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
G-protein coupled photoreceptor activity ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
photoreceptor activity IEA
Inferred from Electronic Annotation
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
detection of visible light IMP
Inferred from Mutant Phenotype
more info
PubMed 
phototransduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
phototransduction ISO
Inferred from Sequence Orthology
more info
 
protein-chromophore linkage IEA
Inferred from Electronic Annotation
more info
 
regulation of circadian rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to stimulus IEA
Inferred from Electronic Annotation
more info
 
rhodopsin mediated signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
rhythmic process IEA
Inferred from Electronic Annotation
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
visual perception IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane TAS
Traceable Author Statement
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
melanopsin
Names
melanopsin
opsin-4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128599.1NP_001122071.1  melanopsin isoform 2

    See proteins identical to NP_001122071.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes an alternate exon in the 3' coding region and 3' UTR. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC114543
    Consensus CDS
    CCDS49446.1
    UniProtKB/Swiss-Prot
    Q9QXZ9
    Related
    ENSMUSP00000126136, ENSMUST00000168444
    Conserved Domains (2) summary
    pfam00001
    Location:92347
    Blast Score: 477
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10328
    Location:77244
    Blast Score: 136
    7TM_GPCR_Srx; Serpentine type 7TM GPCR chemoreceptor Srx
  2. NM_013887.2NP_038915.1  melanopsin isoform 1

    See proteins identical to NP_038915.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1).
    Source sequence(s)
    AC114543
    Consensus CDS
    CCDS26943.1
    UniProtKB/Swiss-Prot
    Q9QXZ9
    Related
    ENSMUSP00000022331, ENSMUST00000022331
    Conserved Domains (2) summary
    pfam00001
    Location:92347
    Blast Score: 489
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    pfam10328
    Location:77244
    Blast Score: 142
    7TM_GPCR_Srx; Serpentine type 7TM GPCR chemoreceptor Srx

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000080.6 

    Range
    34590618..34600142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000036.1 

    Range
    30856294..30865818
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)