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    Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 [ Mus musculus (house mouse) ]

    Gene ID: 16522, updated on 27-Aug-2016
    Official Symbol
    Kcnj6provided by MGI
    Official Full Name
    potassium inwardly-rectifying channel, subfamily J, member 6provided by MGI
    Primary source
    MGI:MGI:104781
    See related
    Ensembl:ENSMUSG00000043301
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    wv; BIR1; GIRK2; KATP2; KCNJ7; Kir3.2; weaver
    Orthologs
    Location:
    16 C4; 16 55.44 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (94748683..94997696, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (94970290..95219303, complement)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41504 Neighboring gene predicted gene, 41507 Neighboring gene predicted gene, 41505 Neighboring gene predicted gene, 31407 Neighboring gene predicted gene, 31641 Neighboring gene predicted gene, 31754

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein activated inward rectifier potassium channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    G-protein alpha-subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    inward rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    voltage-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    potassium ion import IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    thyroid hormone metabolic process IMP
    Inferred from Mutant Phenotype
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    axon ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    neuronal cell body membrane ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    G protein-activated inward rectifier potassium channel 2
    Names
    G-protein-coupled inward rectifier K+ channel 2-1
    G-protein-coupled inward rectifier K+ channel 2-A
    G-protein-coupled inward rectifier K+ channel 2-B
    G-protein-coupled inward rectifier K+ channel 2-C
    GIRK-2
    inward rectifier K(+) channel Kir3.2
    potassium channel, inwardly rectifying subfamily J member 6
    potassium inwardly-rectifying channel J6

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025584.2NP_001020755.1  G protein-activated inward rectifier potassium channel 2 isoform Girk2-1

      See identical proteins and their annotated locations for NP_001020755.1

      Status: VALIDATED

      Source sequence(s)
      AK081109, BB591362
      Consensus CDS
      CCDS37408.1
      UniProtKB/TrEMBL
      Q8C4T8
      Related
      ENSMUSP00000093558, ENSMUST00000095873
      Conserved Domains (1) summary
      pfam01007
      Location:59380
      IRK; Inward rectifier potassium channel
    2. NM_001025585.2NP_001020756.1  G protein-activated inward rectifier potassium channel 2 isoform Girk2B

      See identical proteins and their annotated locations for NP_001020756.1

      Status: VALIDATED

      Source sequence(s)
      BB277039, BB591362, D86040
      UniProtKB/Swiss-Prot
      P48542
      Conserved Domains (1) summary
      cl21560
      Location:59318
      Ion_trans_2; Ion channel
    3. NM_001025590.1NP_001020761.1  G protein-activated inward rectifier potassium channel 2 isoform Girk2C

      See identical proteins and their annotated locations for NP_001020761.1

      Status: VALIDATED

      Source sequence(s)
      AC165248, AK015481
      Consensus CDS
      CCDS49921.1
      UniProtKB/Swiss-Prot
      P48542
      UniProtKB/TrEMBL
      A0A0R4J239
      Related
      ENSMUSP00000130321, ENSMUST00000165538
      Conserved Domains (1) summary
      cl21560
      Location:41302
      Ion_trans_2; Ion channel
    4. NM_010606.2NP_034736.2  G protein-activated inward rectifier potassium channel 2 isoform Girk2A-1

      See identical proteins and their annotated locations for NP_034736.2

      Status: VALIDATED

      Source sequence(s)
      AB029502, AC165271, AK044218, BB591362
      Consensus CDS
      CCDS37409.1
      UniProtKB/Swiss-Prot
      P48542
      UniProtKB/TrEMBL
      Q0VB45, Q8C8Y6
      Related
      ENSMUSP00000097108, ENSMUST00000099508
      Conserved Domains (1) summary
      pfam01007
      Location:59374
      IRK; Inward rectifier potassium channel

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      94748683..94997696 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246104.1XP_011244406.1  

      See identical proteins and their annotated locations for XP_011244406.1

      UniProtKB/Swiss-Prot
      P48542
      Conserved Domains (1) summary
      pfam01007
      Location:41362
      IRK; Inward rectifier potassium channel

    Reference GRCm38.p4 129S6/SvEvTac

    Genomic

    1. NT_039634.4 Reference GRCm38.p4 129S6/SvEvTac

      Range
      631000..878250 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)