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Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25139, updated on 6-May-2015
Official Symbol
Slc2a4provided by RGD
Official Full Name
solute carrier family 2 (facilitated glucose transporter), member 4provided by RGD
Primary source
RGD:2711
See related
Ensembl:ENSRNOG00000017226
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Glut4
Summary
transports glucose; may play a role in insulin response [RGD, Feb 2006]
Orthologs
See Slc2a4 in MapViewer
Location:
10q24
Exon count:
11
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56552983..56558561, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (56298102..56303687, complement)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene G protein pathway suppressor 2 Neighboring gene eukaryotic translation initiation factor 5A Neighboring gene Y box binding protein 2 Neighboring gene cofilin-1-like Neighboring gene claudin 7

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC93607

Gene Ontology Provided by RGD

Function Evidence Code Pubs
D-glucose transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
glucose transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
glucose transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
glucose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
sugar:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
amylopectin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
amylopectin biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
brown fat cell differentiation IEA
Inferred from Electronic Annotation
more info
 
brown fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
cellular response to hypoxia IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to insulin stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to insulin stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to insulin stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to osmotic stress IEA
Inferred from Electronic Annotation
more info
 
cellular response to osmotic stress ISO
Inferred from Sequence Orthology
more info
 
glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 
glucose homeostasis ISO
Inferred from Sequence Orthology
more info
 
glucose import IBA
Inferred from Biological aspect of Ancestor
more info
 
glucose transport IDA
Inferred from Direct Assay
more info
PubMed 
glucose transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
glucose transport ISO
Inferred from Sequence Orthology
more info
 
hexose transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
proton transport IBA
Inferred from Biological aspect of Ancestor
more info
 
response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
T-tubule IDA
Inferred from Direct Assay
more info
PubMed 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
clathrin-coated vesicle ISO
Inferred from Sequence Orthology
more info
 
coated pit IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 
cytosol IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
endomembrane system ISO
Inferred from Sequence Orthology
more info
 
endomembrane system ISS
Inferred from Sequence or Structural Similarity
more info
 
endosome IDA
Inferred from Direct Assay
more info
PubMed 
endosome ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
insulin-responsive compartment IDA
Inferred from Direct Assay
more info
PubMed 
insulin-responsive compartment ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
membrane raft IEA
Inferred from Electronic Annotation
more info
 
membrane raft ISO
Inferred from Sequence Orthology
more info
 
multivesicular body IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 
sarcolemma ISO
Inferred from Sequence Orthology
more info
 
trans-Golgi network transport vesicle IEA
Inferred from Electronic Annotation
more info
 
trans-Golgi network transport vesicle ISO
Inferred from Sequence Orthology
more info
 
Colocalizes_with vesicle IDA
Inferred from Direct Assay
more info
PubMed 
vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
vesicle membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
solute carrier family 2, facilitated glucose transporter member 4
Names
solute carrier family 2, facilitated glucose transporter member 4
GLUT-4
Glucose transporter 4 insuline-responsive
Glucose transporter 4, insuline-responsive
glucose transporter type 4, insulin-responsive
insulin responsive glucose transporter
solute carrier family 2 member 4
solute carrier family 2 , member 4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012751.1NP_036883.1  solute carrier family 2, facilitated glucose transporter member 4

    See identical proteins and their annotated locations for NP_036883.1

    Status: PROVISIONAL

    Source sequence(s)
    D28561
    UniProtKB/Swiss-Prot
    P19357
    Related
    ENSRNOP00000023256, ENSRNOT00000023256
    Conserved Domains (2) summary
    cd06174
    Location:78447
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:28483
    Sugar_tr; Sugar (and other) transporter

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    56552983..56558561
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006246596.2XP_006246658.1  

    See identical proteins and their annotated locations for XP_006246658.1

    UniProtKB/Swiss-Prot
    P19357
    Conserved Domains (2) summary
    cd06174
    Location:78447
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:28483
    Sugar_tr; Sugar (and other) transporter

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    53819953..53825446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)