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Nqo1 NAD(P)H dehydrogenase, quinone 1 [ Mus musculus (house mouse) ]

Gene ID: 18104, updated on 21-Mar-2015
Official Symbol
Nqo1provided by MGI
Official Full Name
NAD(P)H dehydrogenase, quinone 1provided by MGI
Primary source
MGI:MGI:103187
See related
Ensembl:ENSMUSG00000003849; Vega:OTTMUSG00000022884
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dtd; Ox1; Qr1; Dia4; Nmo1; Ox-1; Nmo-1; Nmor1; AV001255
Orthologs
See Nqo1 in MapViewer
Location:
8 D3; 8 54.08 cM
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 8 NC_000074.6 (107388225..107403205, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (109912125..109927105, complement)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein S18, pseudogene 3 Neighboring gene nuclear factor of activated T cells 5 Neighboring gene NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) Neighboring gene ribosomal protein S26, pseudogene 1 Neighboring gene WW domain containing E3 ubiquitin protein ligase 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
NAD(P)H dehydrogenase (quinone) activity IDA
Inferred from Direct Assay
more info
PubMed 
NAD(P)H dehydrogenase (quinone) activity ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
superoxide dismutase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
negative regulation of catalytic activity IDA
Inferred from Direct Assay
more info
PubMed 
oxidation-reduction process IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
removal of superoxide radicals ISO
Inferred from Sequence Orthology
more info
 
response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
superoxide metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
NAD(P)H dehydrogenase [quinone] 1
Names
NAD(P)H dehydrogenase [quinone] 1
DT-diaphorase
NAD(P)H dehydrogenase (quinone)
NAD(P)H menadione oxidoreductase 1, dioxin inducible
NAD(P)H:quinone oxidoreductase 1
azoreductase
diaphorase 4 (NADH/NADPH)
menadione reductase
phylloquinone reductase
quinone reductase 1
NP_032732.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_008706.5NP_032732.3  NAD(P)H dehydrogenase [quinone] 1

    See proteins identical to NP_032732.3

    Status: VALIDATED

    Source sequence(s)
    AA982077, AK075568
    Consensus CDS
    CCDS40465.1
    UniProtKB/TrEMBL
    Q542Y0
    UniProtKB/Swiss-Prot
    Q64669
    Related
    ENSMUSP00000003947, OTTMUSP00000026299, ENSMUST00000003947, OTTMUST00000055042
    Conserved Domains (1) summary
    pfam02525
    Location:5212
    Flavodoxin_2; Flavodoxin-like fold

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p3 C57BL/6J

    Range
    107388225..107403205
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000030.1 Alternate Mm_Celera

    Range
    111617929..111633856
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)