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    NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit [ Homo sapiens (human) ]

    Gene ID: 80155, updated on 4-Sep-2016
    Official Symbol
    NAA15provided by HGNC
    Official Full Name
    N(alpha)-acetyltransferase 15, NatA auxiliary subunitprovided by HGNC
    Primary source
    HGNC:HGNC:30782
    See related
    Ensembl:ENSG00000164134 HPRD:10471; MIM:608000; Vega:OTTHUMG00000137363
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Ga19; NATH; TBDN; NARG1; NAT1P; TBDN100
    Summary
    This gene encodes a protein of unknown function. However, similarity to proteins in yeast and other species suggests that this protein may be an N-acetyltransferase. [provided by RefSeq, Jul 2008]
    Orthologs
    Location:
    4q31.1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 4 NC_000004.12 (139301467..139390781)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (140222621..140311935)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 1074, pseudogene Neighboring gene mitochondria localized glutamic acid rich protein Neighboring gene NADH:ubiquinone oxidoreductase subunit C1 Neighboring gene RNA, U6 small nuclear 1214, pseudogene Neighboring gene uncharacterized LOC105377449 Neighboring gene uncharacterized LOC101927451

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    contributes_to acetyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to peptide alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    poly(A) RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    N-terminal peptidyl-methionine acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    N-terminal protein amino acid acetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    NatA complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    N-alpha-acetyltransferase 15, NatA auxiliary subunit
    Names
    N-terminal acetyltransferase
    NMDA receptor regulated 1
    NMDA receptor-regulated protein 1
    gastric cancer antigen Ga19
    protein tubedown-1
    transcriptional coactivator tubedown-100
    tubedown-1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_057175.3NP_476516.1  N-alpha-acetyltransferase 15, NatA auxiliary subunit

      See identical proteins and their annotated locations for NP_476516.1

      Status: VALIDATED

      Source sequence(s)
      AC097376, AY039242, AY112670, BC032642
      Consensus CDS
      CCDS43270.1
      UniProtKB/Swiss-Prot
      Q9BXJ9
      UniProtKB/TrEMBL
      Q58F05
      Related
      ENSP00000296543, OTTHUMP00000174300, ENST00000296543, OTTHUMT00000267839
      Conserved Domains (3) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam12569
      Location:187698
      NARP1; NMDA receptor-regulated protein 1
      pfam13414
      Location:82145
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p7 Primary Assembly

      Range
      139301467..139390781
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005263236.2XP_005263293.1  

      See identical proteins and their annotated locations for XP_005263293.1

      UniProtKB/TrEMBL
      A0A0B4J1W3
      Related
      ENSP00000381920, OTTHUMP00000174301, ENST00000398947, OTTHUMT00000267840
      Conserved Domains (3) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam12569
      Location:187698
      NARP1; NMDA receptor-regulated protein 1
      pfam13414
      Location:82145
      TPR_11; TPR repeat

    Alternate CHM1_1.1

    Genomic

    1. NC_018915.2 Alternate CHM1_1.1

      Range
      140199902..140289175
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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