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Ski ski sarcoma viral oncogene homolog (avian) [ Mus musculus (house mouse) ]

Gene ID: 20481, updated on 20-Feb-2015
Official Symbol
Skiprovided by MGI
Official Full Name
ski sarcoma viral oncogene homolog (avian)provided by MGI
Primary source
MGI:MGI:98310
See related
Ensembl:ENSMUSG00000029050; Vega:OTTMUSG00000010598
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AA062172; AA589460; BC004088; 2310012I02Rik; 2610001A11Rik
Orthologs
See Ski in MapViewer
Location:
4 E2; 4 86.17 cM
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (155154075..155222593, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 10 Neighboring gene RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae) Neighboring gene MORN repeat containing 1 Neighboring gene uncharacterized LOC105247230 Neighboring gene predicted gene, 33187

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC8300

Gene Ontology Provided by MGI

Function Evidence Code Pubs
SMAD binding IBA
Inferred from Biological aspect of Ancestor
more info
 
SMAD binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding IGI
Inferred from Genetic Interaction
more info
PubMed 
histone deacetylase inhibitor activity IGI
Inferred from Genetic Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
repressing transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
 
ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
SMAD protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
anterior/posterior axis specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
bone morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
camera-type eye development IMP
Inferred from Mutant Phenotype
more info
PubMed 
camera-type eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryonic limb morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
face morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
lens morphogenesis in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
myelination in peripheral nervous system IMP
Inferred from Mutant Phenotype
more info
PubMed 
myotube differentiation IDA
Inferred from Direct Assay
more info
PubMed 
myotube differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
myotube differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of BMP signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of BMP signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of Schwann cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of activin receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of catalytic activity IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of fibroblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of histone deacetylation IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transforming growth factor beta receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of transforming growth factor beta receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
neural tube closure IMP
Inferred from Mutant Phenotype
more info
PubMed 
nose morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
olfactory bulb development IMP
Inferred from Mutant Phenotype
more info
PubMed 
palate development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of DNA binding ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IGI
Inferred from Genetic Interaction
more info
PubMed 
protein homotrimerization ISO
Inferred from Sequence Orthology
more info
 
regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
 
retina development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
skeletal muscle fiber development IMP
Inferred from Mutant Phenotype
more info
PubMed 
somatic stem cell maintenance IDA
Inferred from Direct Assay
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
PML body ISO
Inferred from Sequence Orthology
more info
 
centrosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nuclear body ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
PubMed 
transcription factor complex IPI
Inferred from Physical Interaction
more info
PubMed 
transcriptional repressor complex IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
ski oncogene
Names
ski oncogene
C-ski
Sloan-Kettering viral oncogene homolog
proto-oncogene c-Ski

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011385.2NP_035515.2  ski oncogene

    See proteins identical to NP_035515.2

    Status: VALIDATED

    Source sequence(s)
    AL670413, AW491584, CA451127, CA750434, CB722801, CN526656
    Consensus CDS
    CCDS19024.1
    UniProtKB/TrEMBL
    B1AUF1
    Related
    ENSMUSP00000030917, OTTMUSP00000011357, ENSMUST00000030917, OTTMUST00000024745
    Conserved Domains (4) summary
    pfam02437
    Location:93192
    Ski_Sno; SKI/SNO/DAC family
    pfam08782
    Location:219312
    c-SKI_SMAD_bind; c-SKI Smad4 binding domain
    pfam13863
    Location:571706
    DUF4200; Domain of unknown function (DUF4200)
    cl21477
    Location:565707
    FliJ; Flagellar FliJ protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    155154075..155222593
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538685.2XP_006538748.1  

    Conserved Domains (4) summary
    pfam02437
    Location:93192
    Ski_Sno; SKI/SNO/DAC family
    pfam08782
    Location:219312
    c-SKI_SMAD_bind; c-SKI Smad4 binding domain
    pfam13863
    Location:530665
    DUF4200; Domain of unknown function (DUF4200)
    cl21477
    Location:524666
    FliJ; Flagellar FliJ protein

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    157427881..157496342
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)