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RVB2 RuvB family ATP-dependent DNA helicase reptin [ Saccharomyces cerevisiae S288c ]

Gene ID: 855841, updated on 6-Jul-2014
Gene symbol
RVB2
Gene description
RuvB family ATP-dependent DNA helicase reptin
Primary source
SGD:S000006156
Locus tag
YPL235W
Gene type
protein coding
RNA name
RuvB family ATP-dependent DNA helicase reptin
RefSeq status
PROVISIONAL
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
TIH2; TIP48; TIP49B
See RVB2 in MapViewer
Location:
chromosome: XVI
Exon count :
1
Sequence:
Chromosome: XVI; NC_001148.4 (103232..104647)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Sui3p Neighboring gene Env7p Neighboring gene Vma11p Neighboring gene Nsl1p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP-dependent 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
 
contributes_to ATP-dependent 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
ATP-dependent 5'-3' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
ATP-dependent 5'-3' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
nucleoside-triphosphatase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA duplex unwinding IEA
Inferred from Electronic Annotation
more info
 
DNA repair IEA
Inferred from Electronic Annotation
more info
 
box C/D snoRNP assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
chromatin modification IEA
Inferred from Electronic Annotation
more info
 
chromatin remodeling IPI
Inferred from Physical Interaction
more info
PubMed 
histone exchange IPI
Inferred from Physical Interaction
more info
PubMed 
rRNA processing IEA
Inferred from Electronic Annotation
more info
 
rRNA processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
ASTRA complex IDA
Inferred from Direct Assay
more info
PubMed 
Ino80 complex IPI
Inferred from Physical Interaction
more info
 
R2TP complex IDA
Inferred from Direct Assay
more info
PubMed 
R2TP complex IPI
Inferred from Physical Interaction
more info
PubMed 
Swr1 complex IDA
Inferred from Direct Assay
more info
PubMed 
Swr1 complex IPI
Inferred from Physical Interaction
more info
PubMed 
colocalizes_with nuclear telomeric heterochromatin IDA
Inferred from Direct Assay
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
RuvB family ATP-dependent DNA helicase reptin
NP_015089.1
  • ATP-dependent DNA helicase, also known as reptin; member of the AAA+ and RuvB protein families, similar to Rvb1p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 

    Range
    103232..104647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184049.1NP_015089.1  RuvB family ATP-dependent DNA helicase reptin [Saccharomyces cerevisiae S288c]

    See proteins identical to NP_015089.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q12464
    Conserved Domains (2) summary
    pfam06068
    Location:20409
    Blast Score: 1754
    TIP49; TIP49 C-terminus
    COG1224
    Location:4448
    Blast Score: 1846
    TIP49; DNA helicase TIP49, TBP-interacting protein [Transcription]

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