Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Stxbp1 syntaxin binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 20910, updated on 19-Jul-2014
Official Symbol
Stxbp1provided by MGI
Official Full Name
syntaxin binding protein 1provided by MGI
Primary source
MGI:107363
Locus tag
RP23-17P12.13-002
See related
Ensembl:ENSMUSG00000026797; Vega:OTTMUSG00000012527
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ms10g; nsec1; N-sec1; Sxtbp1; Unc18h; MMS10-G; Rb-sec1; Unc18-1; AI317162; AI326233; Munc-18a; Munc18-1
See Stxbp1 in Epigenomics, MapViewer
Location:
2 B; 2 22.09 cM
Exon count :
20
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 2 NC_000068.7 (32787607..32847237, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700019L03 gene Neighboring gene torsin family 2, member A Neighboring gene tetratricopeptide repeat domain 16 Neighboring gene peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) Neighboring gene family with sequence similarity 129, member B Neighboring gene leucine rich repeat and sterile alpha motif containing 1 Neighboring gene small nucleolar RNA, H/ACA box 65 Neighboring gene ribosomal protein L12

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
SNARE binding ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein N-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
syntaxin binding ISO
Inferred from Sequence Orthology
more info
 
syntaxin-1 binding IPI
Inferred from Physical Interaction
more info
PubMed 
syntaxin-1 binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
axon target recognition IMP
Inferred from Mutant Phenotype
more info
PubMed 
exocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
long term synaptic depression IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of synaptic transmission, GABAergic IDA
Inferred from Direct Assay
more info
PubMed 
neuromuscular synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
neurotransmitter secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
platelet aggregation ISO
Inferred from Sequence Orthology
more info
 
platelet degranulation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of calcium ion-dependent exocytosis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of exocytosis ISO
Inferred from Sequence Orthology
more info
 
protein stabilization ISO
Inferred from Sequence Orthology
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
regulation of synaptic vesicle priming ISO
Inferred from Sequence Orthology
more info
 
synaptic vesicle maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
vesicle docking involved in exocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with plasma membrane ISO
Inferred from Sequence Orthology
more info
 
platelet alpha granule ISO
Inferred from Sequence Orthology
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
syntaxin-binding protein 1
Names
syntaxin-binding protein 1
unc-18A
unc-18-1
UNC-18 homolog
protein unc-18 homolog 1
protein unc-18 homolog A
minisatellite 10g detected by probe MMS10

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113569.1NP_001107041.1  syntaxin-binding protein 1 isoform a

    See proteins identical to NP_001107041.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AK004780, BB852672, BC031728
    Consensus CDS
    CCDS50572.1
    UniProtKB/Swiss-Prot
    O08599
    Related
    ENSMUSP00000089051, OTTMUSP00000013395, ENSMUST00000077458, OTTMUST00000029783
    Conserved Domains (1) summary
    pfam00995
    Location:28582
    Blast Score: 1516
    Sec1; Sec1 family
  2. NM_009295.2NP_033321.2  syntaxin-binding protein 1 isoform b

    See proteins identical to NP_033321.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the coding region, (compared to variant 1), which results in a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AF326563, AK004780, BB852672, BC031728
    Consensus CDS
    CCDS15933.1
    UniProtKB/Swiss-Prot
    O08599
    Related
    ENSMUSP00000052440, OTTMUSP00000013393, ENSMUST00000050000, OTTMUST00000029781
    Conserved Domains (1) summary
    pfam00995
    Location:28582
    Blast Score: 1507
    Sec1; Sec1 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000068.7 

    Range
    32787607..32847237
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000024.1 

    Range
    32494462..32554183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...