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Pnliprp1 pancreatic lipase-related protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 84028, updated on 17-Jan-2015
Official Symbol
Pnliprp1provided by RGD
Official Full Name
pancreatic lipase-related protein 1provided by RGD
Primary source
RGD:620792
See related
Ensembl:ENSRNOG00000017908
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
hydrolyzes dietary triacylglycerols in the duodenum; may play a role in fat metabolism [RGD, Feb 2006]
Orthologs
See Pnliprp1 in MapViewer
Location:
1q55
Exon count:
13
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (279867034..279882663)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (287228054..287243683)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102554592 Neighboring gene pancreatic lipase Neighboring gene pancreatic lipase-related protein 2 Neighboring gene hypothetical protein LOC681006

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
calcium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
lipase activity IDA
Inferred from Direct Assay
more info
PubMed 
NOT lipase activity ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
triglyceride lipase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
pancreas development IEP
Inferred from Expression Pattern
more info
PubMed 
response to glucocorticoid IEP
Inferred from Expression Pattern
more info
PubMed 
response to peptide hormone IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
NOT extracellular space ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
inactive pancreatic lipase-related protein 1
Names
inactive pancreatic lipase-related protein 1
PL-RP1
pancreatic lipase related protein 1
NP_114470.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032081.1NP_114470.1  inactive pancreatic lipase-related protein 1 precursor

    See proteins identical to NP_114470.1

    Status: PROVISIONAL

    Source sequence(s)
    X61925
    UniProtKB/Swiss-Prot
    P54316
    Related
    ENSRNOP00000024164, ENSRNOT00000024164
    Conserved Domains (3) summary
    TIGR03230
    Location:50456
    Lipoprotein_lipase; lipoprotein lipase
    cd00707
    Location:52349
    Pancreat_lipase_like; Pancreatic lipase-like enzymes. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation, ...
    cd01759
    Location:356467
    PLAT_PL; PLAT/LH2 domain of pancreatic triglyceride lipase. Lipases hydrolyze phospholipids and triglycerides to generate fatty acids for energy production or for storage and to release inositol phosphates that act as second messengers. The central role of ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    279867034..279882663
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    253523704..253539212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)