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    ELAVL4 ELAV like neuron-specific RNA binding protein 4 [ Homo sapiens (human) ]

    Gene ID: 1996, updated on 3-Jul-2016
    Official Symbol
    ELAVL4provided by HGNC
    Official Full Name
    ELAV like neuron-specific RNA binding protein 4provided by HGNC
    Primary source
    HGNC:HGNC:3315
    See related
    Ensembl:ENSG00000162374 HPRD:01343; MIM:168360; Vega:OTTHUMG00000007877
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HUD; PNEM
    Orthologs
    Location:
    1p34
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 1 NC_000001.11 (50048014..50203786)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (50513686..50669442)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATP/GTP binding protein like 4 Neighboring gene uncharacterized LOC105378708 Neighboring gene uncharacterized LOC105378709 Neighboring gene mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 pseudogene 29 Neighboring gene uncharacterized LOC107984955 Neighboring gene uncharacterized LOC105378711 Neighboring gene uncharacterized LOC105378710 Neighboring gene uncharacterized LOC105378712

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NHGRI GWAS Catalog

    Description
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    NHGRI GWA Catalog
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    AU-rich element binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA binding TAS
    Traceable Author Statement
    more info
    PubMed 
    mRNA 3'-UTR binding TAS
    Traceable Author Statement
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    RNA processing TAS
    Traceable Author Statement
    more info
    PubMed 
    mRNA processing TAS
    Traceable Author Statement
    more info
    PubMed 
    Preferred Names
    ELAV-like protein 4
    Names
    ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
    Hu antigen D
    paraneoplastic encephalomyelitis antigen HuD

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001144774.2NP_001138246.1  ELAV-like protein 4 isoform 2

      See identical proteins and their annotated locations for NP_001138246.1

      Status: VALIDATED

      Source sequence(s)
      AL592182, AY033997, BC036071, CK005107
      Consensus CDS
      CCDS44140.1
      UniProtKB/Swiss-Prot
      P26378
      Related
      ENSP00000360889, OTTHUMP00000009611, ENST00000371824, OTTHUMT00000021711
      Conserved Domains (4) summary
      cd12650
      Location:45122
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:280365
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:43365
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:127216
      RRM_SF; RNA recognition motif (RRM) superfamily
    2. NM_001144775.2NP_001138247.2  ELAV-like protein 4 isoform 3

      See identical proteins and their annotated locations for NP_001138247.2

      Status: VALIDATED

      Source sequence(s)
      AL592182, AY033996, BC036071, BM509527
      Consensus CDS
      CCDS44139.2
      UniProtKB/Swiss-Prot
      P26378
      UniProtKB/TrEMBL
      A0A0R4J2E6
      Related
      ENSP00000349594, OTTHUMP00000009610, ENST00000357083, OTTHUMT00000021710
      Conserved Domains (4) summary
      cd12650
      Location:81158
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:316401
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      cd12775
      Location:163252
      RRM2_HuB; RNA recognition motif 2 in vertebrate Hu-antigen B (HuB)
      TIGR01661
      Location:79401
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    3. NM_001144776.2NP_001138248.1  ELAV-like protein 4 isoform 4

      See identical proteins and their annotated locations for NP_001138248.1

      Status: VALIDATED

      Source sequence(s)
      AL592182, AY033995, BC036071
      Consensus CDS
      CCDS44138.1
      UniProtKB/Swiss-Prot
      P26378
      Related
      ENSP00000360892, OTTHUMP00000009609, ENST00000371827, OTTHUMT00000021709
      Conserved Domains (4) summary
      cd12650
      Location:45122
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:280365
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:43365
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:127216
      RRM_SF; RNA recognition motif (RRM) superfamily
    4. NM_001144777.2NP_001138249.1  ELAV-like protein 4 isoform 5

      See identical proteins and their annotated locations for NP_001138249.1

      Status: VALIDATED

      Source sequence(s)
      AL592182, BC036071, DC351092
      Consensus CDS
      CCDS53315.1
      UniProtKB/Swiss-Prot
      P26378
      Related
      ENSP00000399939, ENST00000448907
      Conserved Domains (4) summary
      cd12650
      Location:48125
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:283368
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:46368
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:130219
      RRM_SF; RNA recognition motif (RRM) superfamily
    5. NM_001294348.1NP_001281277.1  ELAV-like protein 4 isoform 6

      See identical proteins and their annotated locations for NP_001281277.1

      Status: VALIDATED

      Source sequence(s)
      AK298902, AL583843, AL592182, BC036071
      Consensus CDS
      CCDS72788.1
      UniProtKB/Swiss-Prot
      P26378
      UniProtKB/TrEMBL
      B1APY9
      Related
      ENSP00000360884, OTTHUMP00000009614, ENST00000371819, OTTHUMT00000021714
      Conserved Domains (4) summary
      cd12650
      Location:50127
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:285370
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:48370
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:132221
      RRM_SF; RNA recognition motif (RRM) superfamily
    6. NM_001324208.1NP_001311137.1  ELAV-like protein 4 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182, AL645730
    7. NM_001324209.1NP_001311138.1  ELAV-like protein 4 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182
    8. NM_001324212.1NP_001311141.1  ELAV-like protein 4 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182
    9. NM_001324213.1NP_001311142.1  ELAV-like protein 4 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182
      UniProtKB/TrEMBL
      B1APY8
      Related
      ENSP00000360886, OTTHUMP00000009613, ENST00000371821, OTTHUMT00000021713
    10. NM_001324214.1NP_001311143.1  ELAV-like protein 4 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182
    11. NM_001324215.1NP_001311144.1  ELAV-like protein 4 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182
    12. NM_001324216.1NP_001311145.1  ELAV-like protein 4 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182
    13. NM_001324217.1NP_001311146.1  ELAV-like protein 4 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182
    14. NM_021952.4NP_068771.2  ELAV-like protein 4 isoform 1

      See identical proteins and their annotated locations for NP_068771.2

      Status: VALIDATED

      Source sequence(s)
      AL592182, AY033998, BC036071, CK005107
      Consensus CDS
      CCDS553.1
      UniProtKB/Swiss-Prot
      P26378
      Related
      ENSP00000360888, OTTHUMP00000009612, ENST00000371823, OTTHUMT00000021712
      Conserved Domains (4) summary
      cd12650
      Location:45122
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:294379
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:43379
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:127216
      RRM_SF; RNA recognition motif (RRM) superfamily

    RNA

    1. NR_136725.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL583843, AL592182

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p7 Primary Assembly

      Range
      50048014..50203786
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017000542.1XP_016856031.1  

    2. XM_011540893.2XP_011539195.1  

      See identical proteins and their annotated locations for XP_011539195.1

      Conserved Domains (4) summary
      cd12650
      Location:45122
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:294379
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:43379
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:127216
      RRM_SF; RNA recognition motif (RRM) superfamily
    3. XM_017000541.1XP_016856030.1  

    4. XM_017000538.1XP_016856027.1  

    5. XM_006710411.3XP_006710474.1  

      See identical proteins and their annotated locations for XP_006710474.1

      Conserved Domains (4) summary
      cd12650
      Location:58135
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:307392
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:56392
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:140229
      RRM_SF; RNA recognition motif (RRM) superfamily
    6. XM_017000540.1XP_016856029.1  

    7. XM_011540889.2XP_011539191.1  

      See identical proteins and their annotated locations for XP_011539191.1

      Conserved Domains (4) summary
      cd12650
      Location:81158
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:330415
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      cd12775
      Location:163252
      RRM2_HuB; RNA recognition motif 2 in vertebrate Hu-antigen B (HuB)
      TIGR01661
      Location:79415
      ELAV_HUD_SF; ELAV/HuD family splicing factor
    8. XM_011540890.2XP_011539192.1  

      See identical proteins and their annotated locations for XP_011539192.1

      Conserved Domains (4) summary
      cd12650
      Location:81158
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:303388
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:79388
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:163252
      RRM_SF; RNA recognition motif (RRM) superfamily
    9. XM_011540895.2XP_011539197.1  

      See identical proteins and their annotated locations for XP_011539197.1

      Conserved Domains (4) summary
      cd12650
      Location:44121
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:293378
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:42378
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:126215
      RRM_SF; RNA recognition motif (RRM) superfamily
    10. XM_011540894.2XP_011539196.1  

      See identical proteins and their annotated locations for XP_011539196.1

      Conserved Domains (4) summary
      cd12650
      Location:44121
      RRM1_Hu; RNA recognition motif 1 in the Hu proteins family
      cd12656
      Location:293378
      RRM3_HuD; RNA recognition motif 3 in vertebrate Hu-antigen D (HuD)
      TIGR01661
      Location:42378
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:126215
      RRM_SF; RNA recognition motif (RRM) superfamily
    11. XM_017000539.1XP_016856028.1  

    Alternate CHM1_1.1

    Genomic

    1. NC_018912.2 Alternate CHM1_1.1

      Range
      50630724..50786493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)