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Cxcr3 chemokine (C-X-C motif) receptor 3 [ Mus musculus (house mouse) ]

Gene ID: 12766, updated on 11-Sep-2014
Official Symbol
Cxcr3provided by MGI
Official Full Name
chemokine (C-X-C motif) receptor 3provided by MGI
Primary source
MGI:1277207
Locus tag
RP23-49C8.4
See related
Ensembl:ENSMUSG00000050232; Vega:OTTMUSG00000018202
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cd183; Cmkar3
See Cxcr3 in Epigenomics, MapViewer
Location:
X D; X 44.58 cM
Exon count:
2
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) X NC_000086.7 (101731536..101734147, complement)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene retinitis pigmentosa 1-like 1 protein-like Neighboring gene MARCKS-like 1, pseudogene 5 Neighboring gene tumor protein, translationally-controlled, pseudogene 6 Neighboring gene ribosomal protein SA pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
C-X-C chemokine binding ISO
Inferred from Sequence Orthology
more info
 
C-X-C chemokine receptor activity ISO
Inferred from Sequence Orthology
more info
 
G-protein coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
chemokine binding ISO
Inferred from Sequence Orthology
more info
 
chemokine receptor activity ISO
Inferred from Sequence Orthology
more info
 
receptor activity ISO
Inferred from Sequence Orthology
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
T cell chemotaxis ISO
Inferred from Sequence Orthology
more info
 
angiogenesis IEA
Inferred from Electronic Annotation
more info
 
calcium-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
cell surface receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
chemokine (C-C motif) ligand 11 production ISO
Inferred from Sequence Orthology
more info
 
chemokine-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
chemotaxis IEA
Inferred from Electronic Annotation
more info
 
inflammatory response IEA
Inferred from Electronic Annotation
more info
 
negative regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of execution phase of apoptosis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cAMP metabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cAMP-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of chemotaxis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of execution phase of apoptosis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
regulation of leukocyte migration IEA
Inferred from Electronic Annotation
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell surface IDA
Inferred from Direct Assay
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
C-X-C chemokine receptor type 3
Names
C-X-C chemokine receptor type 3
CXC-R3
CXCR-3
IP-10 receptor
chemokine (C-X-C) receptor 3
interferon-inducible protein 10 receptor

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009910.2NP_034040.1  C-X-C chemokine receptor type 3

    See proteins identical to NP_034040.1

    Status: PROVISIONAL

    Source sequence(s)
    AL805980
    Consensus CDS
    CCDS30319.1
    UniProtKB/Swiss-Prot
    O88410
    Related
    ENSMUSP00000052444, OTTMUSP00000019734, ENSMUST00000056614, OTTMUST00000043946
    Conserved Domains (1) summary
    pfam00001
    Location:75317
    Blast Score: 443
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000086.7 

    Range
    101731536..101734147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000042.1 

    Range
    88649308..88651919
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)