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Crispld2 cysteine-rich secretory protein LCCL domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 171547, updated on 24-Jan-2015
Official Symbol
Crispld2provided by RGD
Official Full Name
cysteine-rich secretory protein LCCL domain containing 2provided by RGD
Primary source
RGD:620860
See related
Ensembl:ENSRNOG00000016752
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Lgl1; Lcrisp2
Summary
may regulate lung development during late gestation; expression is induced by glucocorticoids [RGD, Feb 2006]
Orthologs
See Crispld2 in MapViewer
Location:
19q12
Exon count:
15
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (52647035..52705118)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 19 NC_005118.3 (63394645..63452571)

Chromosome 19 - NC_005118.4Genomic Context describing neighboring genes Neighboring gene kelch-like family member 36 Neighboring gene ubiquitin specific peptidase 10 Neighboring gene zinc finger, DHHC-type containing 7 Neighboring gene forkhead box F1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
glycosaminoglycan binding ISO
Inferred from Sequence Orthology
more info
 
heparin binding IEA
Inferred from Electronic Annotation
more info
 
heparin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 
extracellular matrix organization ISO
Inferred from Sequence Orthology
more info
 
face morphogenesis IEA
Inferred from Electronic Annotation
more info
 
face morphogenesis ISO
Inferred from Sequence Orthology
more info
 
lung development IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
proteinaceous extracellular matrix ISO
Inferred from Sequence Orthology
more info
 
transport vesicle IEA
Inferred from Electronic Annotation
more info
 
transport vesicle ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
cysteine-rich secretory protein LCCL domain-containing 2
Names
cysteine-rich secretory protein LCCL domain-containing 2
late gestation lung protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138518.2NP_612527.2  cysteine-rich secretory protein LCCL domain-containing 2 precursor

    See proteins identical to NP_612527.2

    Status: VALIDATED

    Source sequence(s)
    AABR07044006, AABR07044007, CA509993, CB732240, CK367026, CK600175
    UniProtKB/TrEMBL
    G3V9T1
    Related
    ENSRNOP00000059225, ENSRNOT00000068389
    Conserved Domains (3) summary
    smart00603
    Location:286370
    LCCL; LCCL domain
    cd05380
    Location:56201
    SCP_euk; SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed ...
    pfam03815
    Location:389480
    LCCL; LCCL domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005118.4 Reference Rnor_6.0 Primary Assembly

    Range
    52647035..52705118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255708.2XP_006255770.1  

    See proteins identical to XP_006255770.1

    UniProtKB/TrEMBL
    G3V9T1
    Conserved Domains (3) summary
    smart00603
    Location:286370
    LCCL; LCCL domain
    cd05380
    Location:56201
    SCP_euk; SCP_euk: SCP-like extracellular protein domain, as found mainly in eukaryotes. This family includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5 from vespid venom. It has been proposed ...
    pfam03815
    Location:389480
    LCCL; LCCL domain

Alternate Rn_Celera

Genomic

  1. AC_000087.1 Alternate Rn_Celera

    Range
    47326756..47367597
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)