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    Gtf2h2 general transcription factor II H, polypeptide 2 [ Mus musculus (house mouse) ]

    Gene ID: 23894, updated on 3-Jul-2016
    Official Symbol
    Gtf2h2provided by MGI
    Official Full Name
    general transcription factor II H, polypeptide 2provided by MGI
    Primary source
    MGI:MGI:1345669
    See related
    Ensembl:ENSMUSG00000021639 Vega:OTTMUSG00000023202
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p44; 44kDa; Btf2p44; BTF2 p44; BTF2-p44
    Location:
    13 D1; 13 53.21 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (100460218..100492611, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (101238532..101262564, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 38 pseudogene Neighboring gene ribosomal protein L31, pseudogene 13 Neighboring gene NLR family, apoptosis inhibitory protein 1 Neighboring gene occludin Neighboring gene eukaryotic translation initiation factor 4, gamma 1 pseudogene

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to DNA-dependent ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to RNA polymerase II carboxy-terminal domain kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    G-protein coupled receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    core TFIIH complex IEA
    Inferred from Electronic Annotation
    more info
     
    holo TFIIH complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    general transcription factor IIH subunit 2
    Names
    TFIIH basal transcription factor complex p44 subunit
    basal transcription factor 2, p44 subunit
    basic transcription factor 2 44 kDa subunit
    general transcription factor II H, polypeptide 2 (44 kDa subunit)
    general transcription factor IIH, polypeptide 2 (44 kDa subunit)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022011.4NP_071294.3  general transcription factor IIH subunit 2

      See identical proteins and their annotated locations for NP_071294.3

      Status: VALIDATED

      Source sequence(s)
      BC053382, BY277671, BY480509, DV662169
      Consensus CDS
      CCDS26730.1
      UniProtKB/Swiss-Prot
      Q9JIB4
      UniProtKB/TrEMBL
      Q7TPV0
      Related
      ENSMUSP00000065228, OTTMUSP00000026943, ENSMUST00000066984, OTTMUST00000056139
      Conserved Domains (2) summary
      cd01453
      Location:56236
      vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
      cl06838
      Location:289389
      C1_4; TFIIH C1-like domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      100460218..100492611 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517660.3XP_006517723.1  

      See identical proteins and their annotated locations for XP_006517723.1

      Conserved Domains (2) summary
      cd01453
      Location:56236
      vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
      cl06838
      Location:289389
      C1_4; TFIIH C1-like domain
    2. XM_006517662.3XP_006517725.1  

      See identical proteins and their annotated locations for XP_006517725.1

      Conserved Domains (2) summary
      cd01453
      Location:56236
      vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
      cl06838
      Location:289389
      C1_4; TFIIH C1-like domain

    RNA

    1. XR_873759.2 RNA Sequence

    2. XR_873756.2 RNA Sequence

    3. XR_873758.2 RNA Sequence

      Related
      ENSMUST00000145266, OTTMUST00000056141