Display Settings:

Format

Send to:

Choose Destination
    • Showing Current items.

    GOLM1 golgi membrane protein 1 [ Homo sapiens (human) ]

    Gene ID: 51280, updated on 26-Jun-2015
    Official Symbol
    GOLM1provided by HGNC
    Official Full Name
    golgi membrane protein 1provided by HGNC
    Primary source
    HGNC:HGNC:15451
    See related
    Ensembl:ENSG00000135052; HPRD:08428; MIM:606804; Vega:OTTHUMG00000020130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GP73; HEL46; GOLPH2; C9orf155; PSEC0257; bA379P1.3
    Summary
    The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Sep 2009]
    Orthologs
    See GOLM1 in Epigenomics, MapViewer
    Location:
    9q21.33
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    107 current GRCh38.p2 (GCF_000001405.28) 9 NC_000009.12 (86026141..86100201, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (88629018..88715116, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene ribosomal L1 domain-containing protein 1-like Neighboring gene N(alpha)-acetyltransferase 35, NatC auxiliary subunit Neighboring gene uncharacterized LOC101927623 Neighboring gene chromosome 4 open reading frame 3 pseudogene Neighboring gene chromosome 9 open reading frame 153

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Replication interactions

    Interaction Pubs
    Knockdown of golgi membrane protein 1 (GOLM1; C9orf155) by shRNA library screening inhibits HIV-1 replication in cultured Jurkat T-cells PubMed

    Go to the HIV-1, Human Interaction Database

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Clone Names

    • FLJ22634, FLJ23608

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    nucleus organization IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
     
    extracellular exosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    Preferred Names
    Golgi membrane protein 1
    Names
    Golgi membrane protein 1
    epididymis luminal protein 46
    golgi membrane protein GP73
    golgi phosphoprotein 2
    golgi protein, 73-kD

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016548.3NP_057632.2  Golgi membrane protein 1

      See identical proteins and their annotated locations for NP_057632.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK027717, AL533767, BC001740, CA446701
      Consensus CDS
      CCDS35054.1
      UniProtKB/TrEMBL
      B3KNK9
      UniProtKB/Swiss-Prot
      Q8NBJ4
      Related
      ENSP00000373364, OTTHUMP00000021582, ENST00000388712, OTTHUMT00000052904
      Conserved Domains (1) summary
      TIGR02169
      Location:41211
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    2. NM_177937.2NP_808800.1  Golgi membrane protein 1

      See identical proteins and their annotated locations for NP_808800.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK075557, BC001740, CA446701, DA116177
      Consensus CDS
      CCDS35054.1
      UniProtKB/TrEMBL
      B3KNK9
      UniProtKB/Swiss-Prot
      Q8NBJ4
      Related
      ENSP00000373363, OTTHUMP00000021583, ENST00000388711, OTTHUMT00000052905
      Conserved Domains (1) summary
      TIGR02169
      Location:41211
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p2 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p2 Primary Assembly

      Range
      86026141..86100201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018920.2 Alternate CHM1_1.1

      Range
      88787586..88861938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001099268.1: Suppressed sequence

      Description
      NM_001099268.1: This RefSeq was permanently suppressed because it is primarily intronic sequence.