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iscS cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947004, updated on 14-Sep-2014
Gene symbol
iscS
Gene description
cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent
Primary source
EcoGene:EG12677
Locus tag
b2530
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
Also known as
ECK2527; JW2514; nuvC; yfhO; yzzO
Summary
IscS desulfurase from cysteine via a Cys328 persulfide to binding partners as a transpersulfidase with ThiI Cys456 for tRNA s(4)U8 modification and with SirA(TusA) Cys19 to thiolate tRNA U34. [More information is available at EcoGene: EG12677]. Cysteine desulfurase (IcsC) catalyzes the transfer of sulfur and selenium from cysteine and selenocysteine to a range of recipients. [More information is available at EcoCyc: G7325].
Sequence:
NC_000913.3 (2660317..2661531, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene FeS cluster assembly protein Neighboring gene iron-sulfur cluster assembly scaffold protein Neighboring gene isc operon transcriptional repressor; suf operon transcriptional activator; oxidative stress- and iron starvation-inducible; autorepressor Neighboring gene tRNA mC32,mU32 2'-O-methyltransferase, SAM-dependent

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

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Products Interactant Other Gene Complex Source Pubs Description
Names
cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent
YP_026169.1
  • cysteine desulfurase~cysteine desulfurase (tRNA sulfurtransferase) PLP-dependent

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 

    Range
    2660317..2661531
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026169.1 cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent [Escherichia coli str. K-12 substr. MG1655]

    See proteins identical to YP_026169.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A6B7
    Conserved Domains (1) summary
    PRK14012
    Location:1404
    PRK14012; cysteine desulfurase; Provisional