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    ATP2C1 ATPase secretory pathway Ca2+ transporting 1 [ Homo sapiens (human) ]

    Gene ID: 27032, updated on 13-Aug-2016
    Official Symbol
    ATP2C1provided by HGNC
    Official Full Name
    ATPase secretory pathway Ca2+ transporting 1provided by HGNC
    Primary source
    HGNC:HGNC:13211
    See related
    Ensembl:ENSG00000017260 HPRD:05089; MIM:604384; Vega:OTTHUMG00000136802
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HHD; BCPM; PMR1; SPCA1; hSPCA1; ATP2C1A
    Summary
    The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
    Orthologs
    Location:
    3q22.1
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 3 NC_000003.12 (130850500..131016712)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (130569327..130735556)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986023 Neighboring gene uncharacterized LOC105374107 Neighboring gene uncharacterized LOC105374108 Neighboring gene glutathione S-transferase omega 3, pseudogene Neighboring gene cysteine and glycine rich protein 2 pseudogene Neighboring gene makorin ring finger protein 1 pseudogene Neighboring gene uncharacterized LOC107986024 Neighboring gene asteroid homolog 1 (Drosophila) Neighboring gene NIMA related kinase 11 Neighboring gene RNA, U6 small nuclear 726, pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • KIAA1347

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    calcium-transporting ATPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium-transporting ATPase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    signal transducer activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    Golgi calcium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Golgi calcium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    actin cytoskeleton reorganization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    calcium ion transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular calcium ion homeostasis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular calcium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    epidermis development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ion transmembrane transport TAS
    Traceable Author Statement
    more info
     
    positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Golgi membrane TAS
    Traceable Author Statement
    more info
     
    integral component of membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    calcium-transporting ATPase type 2C member 1
    Names
    ATP-dependent Ca(2+) pump PMR1
    ATPase 2C1
    ATPase, Ca(2+)-sequestering
    ATPase, Ca++ transporting, type 2C, member 1
    HUSSY-28
    secretory pathway Ca2+/Mn2+ ATPase 1
    NP_001001485.1
    NP_001001486.1
    NP_001001487.1
    NP_001186108.1
    NP_001186109.1
    NP_001186110.1
    NP_001186111.1
    NP_001186112.1
    NP_001186113.1
    NP_001186114.1
    NP_055197.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_007379.2 RefSeqGene

      Range
      49066..171188
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001001485.2NP_001001485.1  calcium-transporting ATPase type 2C member 1 isoform 1c

      See identical proteins and their annotated locations for NP_001001485.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) has an alternate 5' sequence and lacks an internal exon in the 3' region, as compared to variant 6. The resulting isoform (1c) has shorter and distinct N- and C-termini, as compared to isoform 2a. Variants 3 and 11 encode the same isoform 1c.
      Source sequence(s)
      AF225981, BC028139, DA405579
      Consensus CDS
      CCDS46913.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000432956, ENST00000533801
      Conserved Domains (6) summary
      cd01427
      Location:551661
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      TIGR01522
      Location:23878
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      pfam00122
      Location:106340
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726880
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:409493
      Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit
    2. NM_001001486.1NP_001001486.1  calcium-transporting ATPase type 2C member 1 isoform 1d

      See identical proteins and their annotated locations for NP_001001486.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) has an alternate 5' exon and an alternate splice site in the last splice junction, as compared to variant 6. The resulting isoform (1d) has a shorter and distinct N-terminus and an additional segment in the C-terminal region, as compared to isoform 2a.
      Source sequence(s)
      AF225981, AY268375, BC028139
      Consensus CDS
      CCDS33856.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000352665, OTTHUMP00000216253, ENST00000359644, OTTHUMT00000356954
      Conserved Domains (6) summary
      TIGR01522
      Location:23903
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:556679
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:106339
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726898
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:410493
      Cation_ATPase; Cation transport ATPase (P-type)
    3. NM_001001487.1NP_001001487.1  calcium-transporting ATPase type 2C member 1 isoform 1b

      See identical proteins and their annotated locations for NP_001001487.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) has an alternate 5' exon, as compared to variant 6. The resulting isoform (1b) has a shorter and distinct N-terminus, as compared to isoform 2a.
      Source sequence(s)
      AF225981, AY268375, BC028139
      Consensus CDS
      CCDS46912.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000402677, OTTHUMP00000216070, ENST00000422190, OTTHUMT00000356645
      Conserved Domains (6) summary
      TIGR01522
      Location:23903
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:556679
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:106339
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726898
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:410493
      Cation_ATPase; Cation transport ATPase (P-type)
    4. NM_001199179.1NP_001186108.1  calcium-transporting ATPase type 2C member 1 isoform 1a

      See identical proteins and their annotated locations for NP_001186108.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) has an alternate 5' sequence, lacks the 3' exon and contains an alternate 3' segment, as compared to variant 6. The resulting isoform (1a) has shorter and distinct N- and C-termini, as compared to isoform 2a. Variants 1 and 5 encode the same isoform 1a.
      Source sequence(s)
      AB037768, AC055733, BQ220831
      Consensus CDS
      CCDS46914.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000424783, OTTHUMP00000216066, ENST00000508532, OTTHUMT00000356641
      Conserved Domains (6) summary
      TIGR01522
      Location:23903
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:556679
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:106339
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726898
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:410493
      Cation_ATPase; Cation transport ATPase (P-type)
    5. NM_001199180.1NP_001186109.1  calcium-transporting ATPase type 2C member 1 isoform 2a

      See identical proteins and their annotated locations for NP_001186109.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) encodes the longest isoform (2a).
      Source sequence(s)
      AF225981, AK296470, DC422788
      Consensus CDS
      CCDS56278.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000421326, OTTHUMP00000216075, ENST00000507488, OTTHUMT00000356650
      Conserved Domains (6) summary
      cd01427
      Location:585695
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      TIGR01522
      Location:57937
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      pfam00122
      Location:140374
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:760932
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:60128
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:443527
      Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit
    6. NM_001199181.1NP_001186110.1  calcium-transporting ATPase type 2C member 1 isoform 2b

      See identical proteins and their annotated locations for NP_001186110.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) lacks the 3' exon and contains an alternate 3' segment, as compared to variant 6. The resulting isoform (2b) has a shorter and distinct C-terminus, as compared to isoform 2a.
      Source sequence(s)
      AB037768, AK304374, BF669202, BF675663, BQ220831, DC422788
      Consensus CDS
      CCDS75006.1
      UniProtKB/Swiss-Prot
      P98194
      UniProtKB/TrEMBL
      B4E2Q0
      Related
      ENSP00000423774, OTTHUMP00000216074, ENST00000505330, OTTHUMT00000356649
      Conserved Domains (6) summary
      cd01427
      Location:585695
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      TIGR01522
      Location:57937
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      pfam00122
      Location:140374
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:760932
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:60128
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:443527
      Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit
    7. NM_001199182.1NP_001186111.1  calcium-transporting ATPase type 2C member 1 isoform 2c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) lacks an in-frame exon in the 5' CDS and has an alternate splice site in the last splice junction, as compared to variant 6. The resulting isoform (2c) lacks a segment in the N-terminal region and has an additional segment in the C-terminal region, as compared to isoform 2a.
      Source sequence(s)
      AF225981, AK299945, AY268375, DC422788
      Consensus CDS
      CCDS56279.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000425320, OTTHUMP00000216072, ENST00000504381, OTTHUMT00000356647
      Conserved Domains (6) summary
      TIGR01522
      Location:57898
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:551674
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:101334
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:721893
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:1389
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:405488
      Cation_ATPase; Cation transport ATPase (P-type)
    8. NM_001199183.1NP_001186112.1  calcium-transporting ATPase type 2C member 1 isoform 1e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) has an alternate 5' exon, resulting in a downstream AUG start codon, as compared to variant 6. The resulting isoform (1e) is shorter at the N-terminus, as compared to isoform 2a.
      Source sequence(s)
      AF225981, AK304175, DC345627
      Consensus CDS
      CCDS56280.1
      UniProtKB/Swiss-Prot
      P98194
      UniProtKB/TrEMBL
      B4E295
      Related
      ENSP00000422872, OTTHUMP00000216068, ENST00000513801, OTTHUMT00000356643
      Conserved Domains (6) summary
      TIGR01522
      Location:7887
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:540663
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:90323
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:710882
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:1078
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:394477
      Cation_ATPase; Cation transport ATPase (P-type)
    9. NM_001199184.1NP_001186113.1  calcium-transporting ATPase type 2C member 1 isoform 1f

      See identical proteins and their annotated locations for NP_001186113.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) has an alternate 5' exon, resulting in a downstream AUG start codon, lacks the 3' exon and contains an alternate 3' segment, as compared to variant 6. The resulting isoform (1f) is shorter at the N-terminus and has a shorter and distinct C-terminus, as compared to isoform 2a.
      Source sequence(s)
      AC055733, AF189723, BQ220831, DC345627
      Consensus CDS
      CCDS56281.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000423330, OTTHUMP00000216069, ENST00000504948, OTTHUMT00000356644
      Conserved Domains (6) summary
      cd01427
      Location:535645
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      TIGR01522
      Location:7887
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      pfam00122
      Location:90324
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:710882
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:1078
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:393477
      Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit
    10. NM_001199185.1NP_001186114.1  calcium-transporting ATPase type 2C member 1 isoform 1c

      See identical proteins and their annotated locations for NP_001186114.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) has an alternate 5' exon and lacks an internal exon in the 3' region, as compared to variant 6. The resulting isoform (1c) has shorter and distinct N- and C-termini, as compared to isoform 2a. Variants 3 and 11 encode the same isoform 1c.
      Source sequence(s)
      AF181121, AF225981, BC028139, DC343471
      Consensus CDS
      CCDS46913.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000329664, OTTHUMP00000216067, ENST00000328560, OTTHUMT00000356642
      Conserved Domains (6) summary
      cd01427
      Location:551661
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      TIGR01522
      Location:23878
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      pfam00122
      Location:106340
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726880
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:409493
      Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit
    11. NM_014382.3NP_055197.2  calcium-transporting ATPase type 2C member 1 isoform 1a

      See identical proteins and their annotated locations for NP_055197.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) has an alternate 5' exon, lacks the 3' exon and contains an alternate 3' segment, as compared to variant 6. The resulting isoform (1a) has shorter and distinct N- and C-termini, as compared to isoform 2a. Variants 1 and 5 encode the same isoform 1a.
      Source sequence(s)
      AC055733, AF181120, AK314342, BQ220831, DC343471
      Consensus CDS
      CCDS46914.1
      UniProtKB/Swiss-Prot
      P98194
      Related
      ENSP00000395809, OTTHUMP00000216076, ENST00000428331, OTTHUMT00000356651
      Conserved Domains (6) summary
      TIGR01522
      Location:23903
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:556679
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:106339
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726898
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:410493
      Cation_ATPase; Cation transport ATPase (P-type)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p7 Primary Assembly

      Range
      130850500..131016712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005247354.2XP_005247411.1  

      Conserved Domains (6) summary
      cd01427
      Location:585695
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      TIGR01522
      Location:57937
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      pfam00122
      Location:140374
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:760932
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:60128
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:443527
      Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit
    2. XM_005247355.2XP_005247412.1  

      See identical proteins and their annotated locations for XP_005247412.1

      UniProtKB/Swiss-Prot
      P98194
      Conserved Domains (6) summary
      TIGR01522
      Location:23903
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:556679
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:106339
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726898
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:410493
      Cation_ATPase; Cation transport ATPase (P-type)
    3. XM_005247356.2XP_005247413.1  

      See identical proteins and their annotated locations for XP_005247413.1

      UniProtKB/Swiss-Prot
      P98194
      Conserved Domains (6) summary
      TIGR01522
      Location:23903
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:556679
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:106339
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726898
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:410493
      Cation_ATPase; Cation transport ATPase (P-type)
    4. XM_017006164.1XP_016861653.1  

      Conserved Domains (6) summary
      TIGR01522
      Location:23903
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      COG4087
      Location:556679
      COG4087; Soluble P-type ATPase [General function prediction only]
      pfam00122
      Location:106339
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:726898
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:2694
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:410493
      Cation_ATPase; Cation transport ATPase (P-type)
    5. XM_005247358.2XP_005247415.1  

      Related
      ENSP00000425228, OTTHUMP00000216071, ENST00000504612, OTTHUMT00000356646
      Conserved Domains (6) summary
      cd01427
      Location:535645
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      TIGR01522
      Location:7887
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      pfam00122
      Location:90324
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:710882
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:1078
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:393477
      Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit
    6. XM_011512686.2XP_011510988.1  

      Conserved Domains (4) summary
      cd01427
      Location:273383
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      pfam00122
      Location:962
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:448620
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam13246
      Location:131215
      Hydrolase_like2; Putative hydrolase of sodium-potassium ATPase alpha subunit

    Alternate CHM1_1.1

    Genomic

    1. NC_018914.2 Alternate CHM1_1.1

      Range
      130532422..130699080
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)