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    Tlx3 T cell leukemia, homeobox 3 [ Mus musculus (house mouse) ]

    Gene ID: 27140, updated on 4-Sep-2016
    Official Symbol
    Tlx3provided by MGI
    Official Full Name
    T cell leukemia, homeobox 3provided by MGI
    Primary source
    MGI:MGI:1351209
    See related
    Ensembl:ENSMUSG00000040610 Vega:OTTMUSG00000005392
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rnx; Tlx1l2; Hox11l2
    Orthologs
    Location:
    11; 11 A5
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (33200752..33203588, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (33100752..33103588, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene nucleophosmin 1 Neighboring gene predicted gene 12115 Neighboring gene RAN binding protein 17 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene acidic (leucine-rich) nuclear phosphoprotein 32 family, pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3)  1 citation
    • Chemically induced (ENU) (1) 
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell fate specification IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cell fate specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    central nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of neuron differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron fate specification IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of respiratory gaseous exchange by neurological system process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    respiratory gaseous exchange IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    T-cell leukemia homeobox protein 3
    Names
    homeo box 11-like 2
    homeobox TLX-3
    homeobox protein Hox-11L2
    respiratory neuron homeobox protein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019916.2NP_064300.2  T-cell leukemia homeobox protein 3

      See identical proteins and their annotated locations for NP_064300.2

      Status: VALIDATED

      Source sequence(s)
      AK141870, AW493622
      Consensus CDS
      CCDS24533.1
      UniProtKB/Swiss-Prot
      O55144
      Related
      ENSMUSP00000047457, OTTMUSP00000005571, ENSMUST00000037746, OTTMUST00000012022
      Conserved Domains (1) summary
      pfam00046
      Location:169222
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      33200752..33203588 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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