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Sorcs1 VPS10 domain receptor protein SORCS 1 [ Mus musculus (house mouse) ]

Gene ID: 58178, updated on 4-Jul-2014
Official Symbol
Sorcs1provided by MGI
Official Full Name
VPS10 domain receptor protein SORCS 1provided by MGI
Primary source
MGI:1929666
See related
Ensembl:ENSMUSG00000043531
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sorcs; mSorCS
See Sorcs1 in Epigenomics, MapViewer
Location:
19 D2; 19 45.05 cM
Exon count :
28
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 19 NC_000085.6 (50143301..50679147, complement)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene seven in absentia 1, pseudogene 1 Neighboring gene ribosomal protein 13A, pseudogene 1 Neighboring gene uncharacterized LOC102631907 Neighboring gene uncharacterized LOC102631841 Neighboring gene ribosomal protein L31, pseudogene 18 Neighboring gene crumbs homolog 1 pseudogene

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
VPS10 domain-containing receptor SorCS1
Names
VPS10 domain-containing receptor SorCS1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252501.1NP_001239430.1  VPS10 domain-containing receptor SorCS1 isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is longer than isoform 1.
    Source sequence(s)
    AC100726, AC131103, AK030440, BE655207
    UniProtKB/TrEMBL
    Q8BSV0
    Related
    ENSMUSP00000072472, ENSMUST00000072685
    Conserved Domains (2) summary
    smart00602
    Location:196793
    Blast Score: 1999
    VPS10; VPS10 domain
    pfam00801
    Location:810880
    Blast Score: 117
    PKD; PKD domain
  2. NM_001290356.1NP_001277285.1  VPS10 domain-containing receptor SorCS1 isoform 3 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC100726, AC101745, AC131103, AC158463, AK030440
    UniProtKB/TrEMBL
    Q8BSV0
    Conserved Domains (2) summary
    smart00602
    Location:196793
    Blast Score: 2001
    VPS10; VPS10 domain
    pfam00801
    Location:807880
    Blast Score: 117
    PKD; PKD domain
  3. NM_021377.3NP_067352.2  VPS10 domain-containing receptor SorCS1 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1.
    Source sequence(s)
    AC100726, AC101745, AC131103, AC158463
    Related
    ENSMUSP00000132615, ENSMUST00000164039
    Conserved Domains (2) summary
    smart00602
    Location:196793
    Blast Score: 2008
    VPS10; VPS10 domain
    pfam00801
    Location:807880
    Blast Score: 117
    PKD; PKD domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000085.6 

    Range
    50143301..50679147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527244.1XP_006527307.1  

    Conserved Domains (2) summary
    smart00602
    Location:196793
    Blast Score: 2004
    VPS10; VPS10 domain
    pfam00801
    Location:807880
    Blast Score: 118
    PKD; PKD domain
  2. XM_006527243.1XP_006527306.1  

    UniProtKB/TrEMBL
    E9Q203
    Conserved Domains (2) summary
    smart00602
    Location:1316
    Blast Score: 1150
    VPS10; VPS10 domain
    pfam00801
    Location:330403
    Blast Score: 118
    PKD; PKD domain
  3. XM_006527242.1XP_006527305.1  

    Related
    ENSMUSP00000107386, ENSMUST00000111756
    Conserved Domains (2) summary
    smart00602
    Location:196793
    Blast Score: 2005
    VPS10; VPS10 domain
    pfam00801
    Location:807880
    Blast Score: 118
    PKD; PKD domain

Alternate Mm_Celera

Genomic

  1. AC_000041.1 

    Range
    50903195..51438098
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

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