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Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 252902, updated on 24-Jan-2015
Official Symbol
Dync1li1provided by RGD
Official Full Name
dynein cytoplasmic 1 light intermediate chain 1provided by RGD
Primary source
RGD:71072
See related
Ensembl:ENSRNOG00000010434
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Dncli1; Dnclic1
Summary
binds the centrosomal protein pericentrin; plays a role in mitotic spindle organization [RGD, Feb 2006]
Orthologs
See Dync1li1 in MapViewer
Location:
8q32
Exon count:
13
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (122743274..122776801)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (122055383..122088910)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene CCR4-NOT transcription complex, subunit 10 Neighboring gene uncharacterized LOC103690467 Neighboring gene uncharacterized LOC100910525 Neighboring gene CKLF-like MARVEL transmembrane domain containing 6 Neighboring gene CKLF-like MARVEL transmembrane domain containing 7

  • Phagosome, organism-specific biosystem (from KEGG)
    Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Phagosome, conserved biosystem (from KEGG)
    Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Salmonella infection, organism-specific biosystem (from KEGG)
    Salmonella infection, organism-specific biosystemSalmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, S...
  • Salmonella infection, conserved biosystem (from KEGG)
    Salmonella infection, conserved biosystemSalmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, S...
  • Vasopressin-regulated water reabsorption, organism-specific biosystem (from KEGG)
    Vasopressin-regulated water reabsorption, organism-specific biosystemIn the kidney, the antidiuretic hormone vasopressin (AVP) is a critical regulator of water homeostasis by controlling the water movement from lumen to the interstitium for water reabsorption and adju...
  • Vasopressin-regulated water reabsorption, conserved biosystem (from KEGG)
    Vasopressin-regulated water reabsorption, conserved biosystemIn the kidney, the antidiuretic hormone vasopressin (AVP) is a critical regulator of water homeostasis by controlling the water movement from lumen to the interstitium for water reabsorption and adju...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell division IEA
Inferred from Electronic Annotation
more info
 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle organization TAS
Traceable Author Statement
more info
PubMed 
positive regulation of mitotic cell cycle spindle assembly checkpoint IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mitotic cell cycle spindle assembly checkpoint ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitotic cell cycle spindle assembly checkpoint ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of centrosome cycle IDA
Inferred from Direct Assay
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
centrosome IEA
Inferred from Electronic Annotation
more info
 
centrosome ISO
Inferred from Sequence Orthology
more info
 
condensed chromosome kinetochore IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic dynein complex IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic dynein complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic dynein complex ISS
Inferred from Sequence or Structural Similarity
more info
 
kinetochore IEA
Inferred from Electronic Annotation
more info
 
kinetochore ISO
Inferred from Sequence Orthology
more info
 
kinetochore ISS
Inferred from Sequence or Structural Similarity
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
spindle pole IEA
Inferred from Electronic Annotation
more info
 
spindle pole ISO
Inferred from Sequence Orthology
more info
 
spindle pole ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
cytoplasmic dynein 1 light intermediate chain 1
Names
cytoplasmic dynein 1 light intermediate chain 1
DLC-A
dynein light chain A
dynein light intermediate chain 1, cytosolic
dynein, cytoplasmic, light intermediate chain 1
dynein, cytoplasmic, light intermediate polypeptide 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145772.1NP_665715.1  cytoplasmic dynein 1 light intermediate chain 1

    See proteins identical to NP_665715.1

    Status: PROVISIONAL

    Source sequence(s)
    AF181992
    UniProtKB/Swiss-Prot
    Q9QXU8
    Related
    ENSRNOP00000014532, ENSRNOT00000014532
    Conserved Domains (1) summary
    pfam05783
    Location:43519
    DLIC; Dynein light intermediate chain (DLIC)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 

    Range
    122743274..122776801
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000076.1 

    Range
    113623555..113657074
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)