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NOS1 nitric oxide synthase 1 (neuronal) [ Homo sapiens (human) ]

Gene ID: 4842, updated on 23-Sep-2014
Official Symbol
NOS1provided by HGNC
Official Full Name
nitric oxide synthase 1 (neuronal)provided by HGNC
Primary source
HGNC:HGNC:7872
See related
Ensembl:ENSG00000089250; HPRD:01226; MIM:163731; Vega:OTTHUMG00000137376
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NOS; bNOS; nNOS; IHPS1; N-NOS; NC-NOS
Summary
The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
See NOS1 in Epigenomics, MapViewer
Location:
12q24.22
Exon count:
35
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 12 NC_000012.12 (117208142..117441825, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (117645921..117799607, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene TESC antisense RNA 1 (head to head) Neighboring gene F-box protein 21 Neighboring gene kinase suppressor of ras 2 Neighboring gene replication factor C (activator 1) 5, 36.5kDa

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
NHGRI GWA Catalog

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env Preincubation of human astrocytoma cells with HIV-1 gp120 produces a significant increase of nitrite and PGE2 in cell supernatants; the effect of gp120 on both nitrite and PGE2 production is inhibited by antagonists of NO synthase or cyclooxygenase PubMed
Envelope transmembrane glycoprotein gp41 env The amino terminus of HIV-1 gp41 induces nitric oxide synthase in human glial and astrocyte cultures and that causes the dysregulation of nitric oxide production PubMed
Tat tat Tat treatment causes activation of neuronal nitric oxide synthase (nNOS) through association with NMDA receptors PubMed

Go to the HIV-1, Human Interaction Database

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    Arginine and proline metabolism, organism-specific biosystem
    Arginine and proline metabolism
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    Arginine and proline metabolism
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    Disease, organism-specific biosystemBiological processes are captured in Reactome by identifying the molecules (DNA, RNA, protein, small molecules) involved in them and describing the details of their interactions. From this molecular ...
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    Effects of nitric oxide, organism-specific biosystemNO (Nitric oxide) is an important signalling molecule with vasodilatory and anti-inflammatory effects, indicating a postive role in reducing hypertension and cardiovascular disease. At the same time,...
  • Hemostasis, organism-specific biosystem (from REACTOME)
    Hemostasis, organism-specific biosystemHemostasis is a physiological response that culminates in the arrest of bleeding from an injured vessel. Under normal conditions the vascular endothelium supports vasodilation, inhibits platelet adhe...
  • Latent infection of Homo sapiens with Mycobacterium tuberculosis, organism-specific biosystem (from REACTOME)
    Latent infection of Homo sapiens with Mycobacterium tuberculosis, organism-specific biosystemInfection by Mycobacterium tuberculosis (Mtb) is soon countered by the host's immune system, the organism is however almost never eradicated; ten per cent of infections will develop into "open tuberc...
  • Long-term depression, organism-specific biosystem (from KEGG)
    Long-term depression, organism-specific biosystemCerebellar long-term depression (LTD), thought to be a molecular and cellular basis for cerebellar learning, is a process involving a decrease in the synaptic strength between parallel fiber (PF) and...
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    Long-term depression, conserved biosystemCerebellar long-term depression (LTD), thought to be a molecular and cellular basis for cerebellar learning, is a process involving a decrease in the synaptic strength between parallel fiber (PF) and...
  • Metabolic pathways, organism-specific biosystem (from KEGG)
    Metabolic pathways, organism-specific biosystem
    Metabolic pathways
  • Monoamine Transport, organism-specific biosystem (from WikiPathways)
    Monoamine Transport, organism-specific biosystem
    Monoamine Transport
  • Myometrial Relaxation and Contraction Pathways, organism-specific biosystem (from WikiPathways)
    Myometrial Relaxation and Contraction Pathways, organism-specific biosystemThis pathway illustrates signaling networks implicated in uterine muscle contraction at labor and quiescence throughout gestation (pregnancy). The muscle of the uterus, responsible for contractile ac...
  • Nitric oxide stimulates guanylate cyclase, organism-specific biosystem (from REACTOME)
    Nitric oxide stimulates guanylate cyclase, organism-specific biosystemNitric Oxide (NO) inhibits smooth muscle cell proliferation and migration, oxidation of low-density lipoproteins, and platelet aggregation and adhesion. It can stimulate vasodilatation of the endothe...
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    Phagosomal maturation (early endosomal stage), organism-specific biosystemAlveolar macrophages normally develop their phagosome along the endolysosomal pathway. However, after having internalized Mtb, this development is arrested at an early stage and only includes acidifi...
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  • citrulline-nitric oxide cycle, organism-specific biosystem (from BIOCYC)
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  • superpathway of citrulline metabolism, organism-specific biosystem (from BIOCYC)
    superpathway of citrulline metabolism, organism-specific biosystem
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Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
FMN binding ISS
Inferred from Sequence or Structural Similarity
more info
 
NADP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
NADPH-hemoprotein reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
arginine binding TAS
Traceable Author Statement
more info
PubMed 
cadmium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
flavin adenine dinucleotide binding ISS
Inferred from Sequence or Structural Similarity
more info
 
heme binding ISS
Inferred from Sequence or Structural Similarity
more info
 
ion channel binding ISS
Inferred from Sequence or Structural Similarity
more info
 
iron ion binding IEA
Inferred from Electronic Annotation
more info
 
nitric-oxide synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
nitric-oxide synthase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
scaffold protein binding ISS
Inferred from Sequence or Structural Similarity
more info
 
sodium channel regulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
tetrahydrobiopterin binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
arginine catabolic process IC
Inferred by Curator
more info
PubMed 
blood coagulation TAS
Traceable Author Statement
more info
 
cellular response to growth factor stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
exogenous drug catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
interaction with host TAS
Traceable Author Statement
more info
 
multicellular organismal response to stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
myoblast fusion TAS
Traceable Author Statement
more info
PubMed 
negative regulation of blood pressure IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of calcium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of calcium ion transport into cytosol TAS
Traceable Author Statement
more info
PubMed 
negative regulation of hydrolase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of potassium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of serotonin uptake ISS
Inferred from Sequence or Structural Similarity
more info
 
neurotransmitter biosynthetic process TAS
Traceable Author Statement
more info
PubMed 
nitric oxide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
nitric oxide biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
nitric oxide mediated signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
peptidyl-cysteine S-nitrosylation ISS
Inferred from Sequence or Structural Similarity
more info
 
phagosome maturation TAS
Traceable Author Statement
more info
 
positive regulation of guanylate cyclase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of histone acetylation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of sodium ion transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of the force of heart contraction ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription from RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of vasodilation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of vasodilation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cardiac muscle contraction TAS
Traceable Author Statement
more info
PubMed 
regulation of sodium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
 
response to heat IDA
Inferred from Direct Assay
more info
PubMed 
response to hypoxia IEP
Inferred from Expression Pattern
more info
PubMed 
striated muscle contraction ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoplasm TAS
Traceable Author Statement
more info
PubMed 
cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol TAS
Traceable Author Statement
more info
 
dendritic spine IEA
Inferred from Electronic Annotation
more info
 
membrane raft ISS
Inferred from Sequence or Structural Similarity
more info
 
mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 
perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
photoreceptor inner segment ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
protein complex ISS
Inferred from Sequence or Structural Similarity
more info
 
sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 
sarcoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
synapse ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
nitric oxide synthase, brain
Names
nitric oxide synthase, brain
NOS type I
neuronal NOS
constitutive NOS
peptidyl-cysteine S-nitrosylase NOS1
NP_000611.1
NP_001191142.1
NP_001191143.1
NP_001191147.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_011991.2 

    Range
    4976..158636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_000620.4NP_000611.1  nitric oxide synthase, brain isoform 1

    See proteins identical to NP_000611.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1 (also known as nNOS).
    Source sequence(s)
    AC026364, AK294435, AK307481, BC033208, BE207961, U17327
    Consensus CDS
    CCDS41842.1
    UniProtKB/TrEMBL
    A0PJJ7
    UniProtKB/TrEMBL
    B3VK56
    UniProtKB/TrEMBL
    B4DG68
    UniProtKB/Swiss-Prot
    P29475
    Related
    ENSP00000320758, OTTHUMP00000174427, ENST00000317775, OTTHUMT00000268052
    Conserved Domains (6) summary
    cd06202
    Location:10011404
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    pfam11035
    Location:119232
    SnAPC_2_like; Small nuclear RNA activating complex subunit 2-like
    COG0369
    Location:7591399
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    cd00795
    Location:305716
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:1598
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00258
    Location:762935
    Flavodoxin_1; Flavodoxin
  2. NM_001204213.1NP_001191142.1  nitric oxide synthase, brain isoform 3

    See proteins identical to NP_001191142.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3, also known as TnNOS) contains 2 unique alternate exons (Tex 1 and Tex 2) at the 5' end compared to variant 1, resulting in translation initiation from a downstream AUG, and an isoform (isoform 3, also known as nNOSgamma) with a shorter N-terminus compared to isoform 1. This variant is specifically expressed in the testis, and the encoded isoform has catalytic activity (PMID:9111048). Variants 3 and 4 encode the same isoform.
    Source sequence(s)
    AC026364, AC068799, AK294435, AK307481, BC033208, BE207961, U17327
    UniProtKB/TrEMBL
    A0PJJ7
    UniProtKB/TrEMBL
    B4DG68
    UniProtKB/Swiss-Prot
    P29475
    Conserved Domains (4) summary
    cd06202
    Location:6651068
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    COG0369
    Location:4231063
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    cd00795
    Location:1380
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    pfam00258
    Location:426599
    Flavodoxin_1; Flavodoxin
  3. NM_001204214.1NP_001191143.1  nitric oxide synthase, brain isoform 3

    See proteins identical to NP_001191143.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4, also known as TnNOSb) contains 2 unique alternate exons (Tex 1b and Tex 2) at the 5' end compared to variant 1, resulting in translation initiation from a downstream AUG, and an isoform (3, also known as nNOSgamma) with a shorter N-terminus compared to isoform 1. This variant is specifically expressed in the testis, and the encoded isoform has catalytic activity (PMID:9111048). Variants 3 and 4 encode the same isoform.
    Source sequence(s)
    AC026364, AC068799, AK294435, AK307481, BC033208, BE207961, U17327
    UniProtKB/TrEMBL
    A0PJJ7
    UniProtKB/TrEMBL
    B4DG68
    UniProtKB/Swiss-Prot
    P29475
    Conserved Domains (4) summary
    cd06202
    Location:6651068
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    COG0369
    Location:4231063
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    cd00795
    Location:1380
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    pfam00258
    Location:426599
    Flavodoxin_1; Flavodoxin
  4. NM_001204218.1NP_001191147.1  nitric oxide synthase, brain isoform 2

    See proteins identical to NP_001191147.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) contains an additional in-frame coding exon compared to variant 1, resulting in a longer isoform (2, also known as nNOSmu) containing a 34 aa protein segment not found in isoform 1. A similar isoform has also been reported in rat and mouse, and the mouse isoform has been shown to have catalytic activity (PMID:9791007).
    Source sequence(s)
    AC026364, AJ004918, AK294435, AK307481, BC033208, BE207961, U17327
    Consensus CDS
    CCDS55890.1
    UniProtKB/TrEMBL
    A0PJJ7
    UniProtKB/TrEMBL
    B4DG68
    UniProtKB/Swiss-Prot
    P29475
    Related
    ENSP00000477999, ENST00000618760
    Conserved Domains (6) summary
    cd06202
    Location:10351438
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    pfam11035
    Location:119232
    SnAPC_2_like; Small nuclear RNA activating complex subunit 2-like
    COG0369
    Location:7591433
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    cd00795
    Location:305716
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:1598
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00258
    Location:762969
    Flavodoxin_1; Flavodoxin

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000012.12 

    Range
    117208142..117441825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006719428.1XP_006719491.1  

    See proteins identical to XP_006719491.1

    UniProtKB/TrEMBL
    B3VK56
    UniProtKB/Swiss-Prot
    P29475
    Conserved Domains (6) summary
    cd06202
    Location:10011404
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    pfam11035
    Location:119232
    SnAPC_2_like; Small nuclear RNA activating complex subunit 2-like
    COG0369
    Location:7591399
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    cd00795
    Location:305716
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:1598
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00258
    Location:762935
    Flavodoxin_1; Flavodoxin
  2. XM_006719426.1XP_006719489.1  

    See proteins identical to XP_006719489.1

    UniProtKB/Swiss-Prot
    P29475
    Conserved Domains (6) summary
    cd06202
    Location:10351438
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    pfam11035
    Location:119232
    SnAPC_2_like; Small nuclear RNA activating complex subunit 2-like
    COG0369
    Location:7591433
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    cd00795
    Location:305716
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:1598
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00258
    Location:762969
    Flavodoxin_1; Flavodoxin
  3. XM_006719427.1XP_006719490.1  

    See proteins identical to XP_006719490.1

    UniProtKB/Swiss-Prot
    P29475
    Conserved Domains (6) summary
    cd06202
    Location:10351438
    Nitric_oxide_synthase; The ferredoxin-reductase (FNR) like C-terminal domain of the nitric oxide synthase (NOS) fuses with a heme-containing N-terminal oxidase domain. The reductase portion is similar in structure to NADPH dependent cytochrome-450 reductase (CYPOR), having an ...
    pfam11035
    Location:119232
    SnAPC_2_like; Small nuclear RNA activating complex subunit 2-like
    COG0369
    Location:7591433
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    cd00795
    Location:305716
    NOS_oxygenase_euk; Nitric oxide synthase (NOS) eukaryotic oxygenase domain. NOS produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N ...
    cd00992
    Location:1598
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00258
    Location:762969
    Flavodoxin_1; Flavodoxin

RNA

  1. XR_429103.1 RNA Sequence

Alternate HuRef

Genomic

  1. AC_000144.1 

    Range
    114655115..114808727
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 

    Range
    117611241..117767258
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)