Display Settings:

Format

Send to:

Choose Destination

SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 [ Homo sapiens (human) ]

Gene ID: 8884, updated on 18-Oct-2014
Official Symbol
SLC5A6provided by HGNC
Official Full Name
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6provided by HGNC
Primary source
HGNC:HGNC:11041
See related
Ensembl:ENSG00000138074; HPRD:04934; MIM:604024; Vega:OTTHUMG00000097075
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SMVT
See SLC5A6 in Epigenomics, MapViewer
Location:
2p23
Exon count:
19
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 2 NC_000002.12 (27199587..27212307, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (27422455..27435175, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene proline rich 30 Neighboring gene transcription factor 23 Neighboring gene all-trans retinoic acid-induced differentiation factor Neighboring gene carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Neighboring gene solute carrier family 30 (zinc transporter), member 3 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 5 gamma

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
sodium-dependent multivitamin transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
biotin metabolic process TAS
Traceable Author Statement
more info
 
biotin transport IEA
Inferred from Electronic Annotation
more info
 
pantothenate metabolic process TAS
Traceable Author Statement
more info
 
pantothenate transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
small molecule metabolic process TAS
Traceable Author Statement
more info
 
sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
transmembrane transport TAS
Traceable Author Statement
more info
 
transport TAS
Traceable Author Statement
more info
PubMed 
vitamin metabolic process TAS
Traceable Author Statement
more info
 
water-soluble vitamin metabolic process TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
brush border membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
membrane TAS
Traceable Author Statement
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
sodium-dependent multivitamin transporter
Names
sodium-dependent multivitamin transporter
solute carrier family 5 member 6
Na+-dependent multivitamin transporter
Na(+)-dependent multivitamin transporter
solute carrier family 5 (sodium-dependent vitamin transporter), member 6

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021095.2NP_066918.2  sodium-dependent multivitamin transporter

    See proteins identical to NP_066918.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the functional protein.
    Source sequence(s)
    AF069307, AF288781, BC012806, DB452476, N30242
    Consensus CDS
    CCDS1740.1
    UniProtKB/TrEMBL
    Q9HD19
    UniProtKB/Swiss-Prot
    Q9Y289
    Related
    ENSP00000310208, OTTHUMP00000122593, ENST00000310574, OTTHUMT00000214194
    Conserved Domains (1) summary
    cd11504
    Location:24550
    SLC5sbd_SMVT; Na(+)/multivitamin cotransporter SMVT and related proteins; solute-binding domain

RNA

  1. NR_028323.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has two differences in the presence and absence of alternate segments, compared to variant 1. This variant is represented as non-coding because the use of the 5' most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK027855, BG025980, BI832199, BQ651664, DA958474, DB452476, N30242

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000002.12 

    Range
    27199587..27212307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006712129.1XP_006712192.1  

    See proteins identical to XP_006712192.1

    UniProtKB/Swiss-Prot
    Q9Y289
    Conserved Domains (1) summary
    cd11504
    Location:24550
    SLC5sbd_SMVT; Na(+)/multivitamin cotransporter SMVT and related proteins; solute-binding domain
  2. XM_006712130.1XP_006712193.1  

    See proteins identical to XP_006712193.1

    UniProtKB/Swiss-Prot
    Q9Y289
    Conserved Domains (1) summary
    cd11504
    Location:24550
    SLC5sbd_SMVT; Na(+)/multivitamin cotransporter SMVT and related proteins; solute-binding domain
  3. XM_006712128.1XP_006712191.1  

    See proteins identical to XP_006712191.1

    UniProtKB/Swiss-Prot
    Q9Y289
    Conserved Domains (1) summary
    cd11504
    Location:24550
    SLC5sbd_SMVT; Na(+)/multivitamin cotransporter SMVT and related proteins; solute-binding domain
  4. XM_006712131.1XP_006712194.1  

    Conserved Domains (1) summary
    cl00456
    Location:24337
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

Alternate HuRef

Genomic

  1. AC_000134.1 

    Range
    27164164..27176880
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018913.2 

    Range
    27352374..27365079
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)