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    PGV1gp1 polyprotein [ Pestivirus Giraffe-1 ]

    Gene ID: 940263, updated on 26-Jun-2015
    Gene symbol
    PGV1gp1
    Gene description
    polyprotein
    Locus tag
    PGV1gp1
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Pestivirus Giraffe-1 (biotype: cytopathic, isolate: giraffe-1 H138, nat-host: Giraffa camelopardalis)
    Lineage
    Viruses; ssRNA positive-strand viruses, no DNA stage; Flaviviridae; Pestivirus
    Sequence:
    NC_003678.1 (383..12352)

    NC_003678.1Genomic Context describing neighboring genes

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Names
    polyprotein
    N-Pro
    capsid protein
    RNAse
    envelope glycoprotein E1
    envelope glycoprotein E2
    E2*
    nonstructural protein p7
    NTPase/RNA helicase (NS3)
    NTPase/RNA helicase
    nonstructural protein NS4A
    nonstructural protein NS4B
    nonstructural protein NS5A
    RNA-dependent RNA polymerase

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003678.1 Reference assembly

      Range
      383..12352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_620053.1 polyprotein [Pestivirus Giraffe-1]

      See identical proteins and their annotated locations for NP_620053.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9PYB2
      Conserved Domains (9) summary
      pfam05578
      Location:16801890
      Peptidase_S31; Pestivirus NS3 polyprotein peptidase S31
      pfam05550
      Location:1168
      Peptidase_C53; Pestivirus Npro endopeptidase C53
      pfam11889
      Location:170218
      DUF3409; Domain of unknown function (DUF3409)
      pfam12387
      Location:13181517
      Peptidase_C74; Pestivirus NS2 peptidase
      cd00046
      Location:19062032
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:20742196
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cd01699
      Location:35123797
      RNA_dep_RNAP; RNA_dep_RNAP: RNA-dependent RNA polymerase (RdRp) is an essential protein encoded in the genomes of all RNA containing viruses with no DNA stage. RdRp catalyzes synthesis of the RNA strand complementary to a given RNA template. RdRps of many viruses are ...
      pfam14901
      Location:15271619
      Jiv90; Cleavage inducing molecular chaperone
      cl00208
      Location:288352
      RNase_T2; Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases). Plant T2 RNases are expressed during leaf ...
    2. NP_777520.1 N-Pro

      Conserved Domains (1) summary
      pfam05550
      Location:1168
      Peptidase_C53; Pestivirus Npro endopeptidase C53
    3. NP_777521.1 capsid protein

      Conserved Domains (1) summary
      pfam11889
      Location:250
      DUF3409; Domain of unknown function (DUF3409)
    4. NP_777522.1 RNAse

      Conserved Domains (1) summary
      cl00208
      Location:2286
      RNase_T2; Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases). Plant T2 RNases are expressed during leaf ...
    5. NP_777523.1 envelope glycoprotein E1

    6. NP_777524.1 envelope glycoprotein E2

    7. NP_777525.1 E2*

    8. NP_777526.1 nonstructural protein p7

    9. NP_777527.1 NTPase/RNA helicase (NS3)

      Conserved Domains (5) summary
      pfam05578
      Location:548758
      Peptidase_S31; Pestivirus NS3 polyprotein peptidase S31
      pfam12387
      Location:186385
      Peptidase_C74; Pestivirus NS2 peptidase
      cd00046
      Location:774900
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:9421064
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam14901
      Location:395487
      Jiv90; Cleavage inducing molecular chaperone
    10. NP_777528.1 NTPase/RNA helicase

      Conserved Domains (3) summary
      pfam05578
      Location:1211
      Peptidase_S31; Pestivirus NS3 polyprotein peptidase S31
      cd00046
      Location:227353
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      cd00079
      Location:395517
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    11. NP_777529.1 nonstructural protein NS4A

    12. NP_777530.1 nonstructural protein NS4B

    13. NP_777531.1 nonstructural protein NS5A

    14. NP_777532.1 RNA-dependent RNA polymerase

      Conserved Domains (1) summary
      cd01699
      Location:242527
      RNA_dep_RNAP; RNA_dep_RNAP: RNA-dependent RNA polymerase (RdRp) is an essential protein encoded in the genomes of all RNA containing viruses with no DNA stage. RdRp catalyzes synthesis of the RNA strand complementary to a given RNA template. RdRps of many viruses are ...