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PLA2G16 phospholipase A2, group XVI [ Homo sapiens (human) ]

Gene ID: 11145, updated on 7-Dec-2014
Official Symbol
PLA2G16provided by HGNC
Official Full Name
phospholipase A2, group XVIprovided by HGNC
Primary source
HGNC:HGNC:17825
See related
Ensembl:ENSG00000176485; HPRD:13671; MIM:613867
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
AdPLA; HRSL3; HRASLS3; HREV107; HREV107-1; HREV107-3; H-REV107-1
See PLA2G16 in Epigenomics, MapViewer
Location:
11q12.3
Exon count:
5
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 11 NC_000011.10 (63574462..63616873, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (63341934..63381941, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene retinoic acid receptor responder (tazarotene induced) 3 Neighboring gene HRAS-like suppressor 2 Neighboring gene IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) pseudogene 1 Neighboring gene atlastin GTPase 3 Neighboring gene reticulon 3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC118754

Gene Ontology Provided by GOA

Function Evidence Code Pubs
1-acyl-2-lysophosphatidylserine acylhydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphatidylcholine 1-acylhydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphatidylserine 1-acylhydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phospholipase A2 activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
glycerophospholipid biosynthetic process TAS
Traceable Author Statement
more info
 
lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
phosphatidylcholine acyl-chain remodeling TAS
Traceable Author Statement
more info
 
phosphatidylethanolamine acyl-chain remodeling TAS
Traceable Author Statement
more info
 
phosphatidylinositol acyl-chain remodeling TAS
Traceable Author Statement
more info
 
phosphatidylserine acyl-chain remodeling TAS
Traceable Author Statement
more info
 
phospholipid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
phospholipid metabolic process TAS
Traceable Author Statement
more info
 
small molecule metabolic process TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytosol TAS
Traceable Author Statement
more info
 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
HRAS-like suppressor 3
Names
HRAS-like suppressor 3
adipose-specific PLA2
HRAS-like suppressor 1
H-rev 107 protein homolog
group XVI phospholipase A2
group XVI phospholipase A1/A2
Ca-independent phospholipase A1/2
adipose-specific phospholipase A2
renal carcinoma antigen NY-REN-65
NP_001121675.1
NP_009000.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128203.1NP_001121675.1  HRAS-like suppressor 3

    See proteins identical to NP_001121675.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AI374456, AI590735, BG719903, CK003948
    Consensus CDS
    CCDS8047.1
    UniProtKB/TrEMBL
    A0A024R561
    UniProtKB/Swiss-Prot
    P53816
    Related
    ENSP00000389124, ENST00000415826
    Conserved Domains (1) summary
    pfam04970
    Location:6125
    LRAT; Lecithin retinol acyltransferase
  2. NM_007069.3NP_009000.2  HRAS-like suppressor 3

    See proteins identical to NP_009000.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AI374456, AI590735, AK313075, AU099540
    Consensus CDS
    CCDS8047.1
    UniProtKB/TrEMBL
    A0A024R561
    UniProtKB/Swiss-Prot
    P53816
    Conserved Domains (1) summary
    pfam04970
    Location:6125
    LRAT; Lecithin retinol acyltransferase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000011.10 

    Range
    63574462..63616873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006718426.1XP_006718489.1  

    See proteins identical to XP_006718489.1

    UniProtKB/TrEMBL
    A0A024R561
    UniProtKB/Swiss-Prot
    P53816
    Conserved Domains (1) summary
    pfam04970
    Location:6125
    LRAT; Lecithin retinol acyltransferase

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 

    Range
    63224977..63264973
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000143.1 

    Range
    59671244..59711239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)