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Pawr PRKC, apoptosis, WT1, regulator [ Mus musculus (house mouse) ]

Gene ID: 114774, updated on 24-Jan-2015
Official Symbol
Pawrprovided by MGI
Official Full Name
PRKC, apoptosis, WT1, regulatorprovided by MGI
Primary source
MGI:MGI:2149961
See related
Ensembl:ENSMUSG00000035873
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PAR4; Par-4; 2310001G03Rik
Orthologs
See Pawr in MapViewer
Location:
10 D1; 10
Exon count:
8
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 10 NC_000076.6 (108332189..108414847)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 29685 Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 12A Neighboring gene predicted gene, 36283 Neighboring gene predicted gene, 36440 Neighboring gene predicted gene, 36601 Neighboring gene synaptotagmin I

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
actin binding ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
leucine zipper domain binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
actin filament bundle assembly ISO
Inferred from Sequence Orthology
more info
 
apoptotic process ISO
Inferred from Sequence Orthology
more info
 
apoptotic signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
interleukin-2 biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of B cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of T cell receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of amyloid precursor protein biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with actin filament ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
PRKC apoptosis WT1 regulator protein
Names
PRKC apoptosis WT1 regulator protein
prostate apoptosis response 4 protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_054056.2NP_473397.1  PRKC apoptosis WT1 regulator protein

    See proteins identical to NP_473397.1

    Status: VALIDATED

    Source sequence(s)
    AW123400, DQ363525, DV057979
    Consensus CDS
    CCDS36053.1
    UniProtKB/Swiss-Prot
    Q925B0
    Related
    ENSMUSP00000092951, ENSMUST00000095313
    Conserved Domains (1) summary
    pfam05911
    Location:261324
    DUF869; Plant protein of unknown function (DUF869)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000076.6 

    Range
    108332189..108414847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513090.1XP_006513153.1  

    Conserved Domains (2) summary
    PLN02627
    Location:1175
    PLN02627; glutamyl-tRNA synthetase
    pfam05911
    Location:328391
    DUF869; Plant protein of unknown function (DUF869)

Alternate Mm_Celera

Genomic

  1. AC_000032.1 

    Range
    110266638..110348648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)