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Ahcy S-adenosylhomocysteine hydrolase [ Mus musculus (house mouse) ]

Gene ID: 269378, updated on 24-Jan-2015
Official Symbol
Ahcyprovided by MGI
Official Full Name
S-adenosylhomocysteine hydrolaseprovided by MGI
Primary source
MGI:MGI:87968
Locus tag
RP23-192A6.3
See related
Ensembl:ENSMUSG00000027597; Vega:OTTMUSG00000016006
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CuBP; SAHH; AA987153; AL024110
Orthologs
See Ahcy in MapViewer
Location:
2 H1; 2 76.94 cM
Exon count:
10
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 2 NC_000068.7 (155059310..155074497, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2, subunit 2 (beta) Neighboring gene uncharacterized LOC102635816 Neighboring gene nonagouti Neighboring gene RIKEN cDNA 2310005A03 gene Neighboring gene predicted gene, 33261 Neighboring gene itchy, E3 ubiquitin protein ligase Neighboring gene proteasome (prosome, macropain) subunit, beta type 3 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (2) 
  • Targeted (1) 

Markers

Homology

Clone Names

  • MGC19228, MGC102079, MGC118063

Gene Ontology Provided by MGI

Function Evidence Code Pubs
NAD binding ISO
Inferred from Sequence Orthology
more info
 
adenosylhomocysteinase activity IDA
Inferred from Direct Assay
more info
PubMed 
adenosylhomocysteinase activity ISO
Inferred from Sequence Orthology
more info
 
adenyl nucleotide binding ISO
Inferred from Sequence Orthology
more info
 
copper ion binding IDA
Inferred from Direct Assay
more info
PubMed 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
protein self-association IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
S-adenosylhomocysteine catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
S-adenosylhomocysteine catabolic process ISO
Inferred from Sequence Orthology
more info
 
S-adenosylmethionine cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
chronic inflammatory response to antigenic stimulus ISO
Inferred from Sequence Orthology
more info
 
circadian sleep/wake cycle ISO
Inferred from Sequence Orthology
more info
 
homocysteine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
response to nutrient ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
neuron projection ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
adenosylhomocysteinase
Names
adenosylhomocysteinase
adoHcyase
liver copper-binding protein
S-adenosyl-L-homocysteine hydrolase
NP_057870.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016661.3NP_057870.3  adenosylhomocysteinase

    See proteins identical to NP_057870.3

    Status: VALIDATED

    Source sequence(s)
    AA237720, AK169331, BC086781, BQ929555
    Consensus CDS
    CCDS16942.1
    UniProtKB/Swiss-Prot
    P50247
    UniProtKB/TrEMBL
    Q3TF14
    UniProtKB/TrEMBL
    Q5M9P0
    Related
    ENSMUSP00000061851, OTTMUSP00000017088, ENSMUST00000054607, OTTMUST00000038111
    Conserved Domains (2) summary
    PRK05476
    Location:1426
    PRK05476; S-adenosyl-L-homocysteine hydrolase; Provisional
    cd00401
    Location:16420
    SAHH; S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000068.7 

    Range
    155059310..155074497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000024.1 

    Range
    160986232..161001420
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)