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MT1E metallothionein 1E [ Homo sapiens (human) ]

Gene ID: 4493, updated on 27-Apr-2015
Official Symbol
MT1Eprovided by HGNC
Official Full Name
metallothionein 1Eprovided by HGNC
Primary source
HGNC:HGNC:7397
See related
HPRD:01126; MIM:156351
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MT1; MTD; MT-1E; MT-IE
Orthologs
See MT1E in MapViewer
Location:
16q13
Exon count:
3
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 16 NC_000016.10 (56625673..56627112)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (56659557..56661024)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371284 Neighboring gene metallothionein 2A Neighboring gene metallothionein 1L (gene/pseudogene) Neighboring gene metallothionein 1M Neighboring gene metallothionein 1J, pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Protein interactions

Protein Gene Interaction Pubs
Tat tat Microarray analysis indicates HIV-1 Tat upregulates the interferon-responsive gene expression of many proteins, including Metallothionein, in immature dendritic cells, an effect that likely facilitates the expansion of HIV-1 infection PubMed

Go to the HIV-1, Human Interaction Database

  • Mineral absorption, organism-specific biosystem (from KEGG)
    Mineral absorption, organism-specific biosystemMinerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an ...
  • Mineral absorption, conserved biosystem (from KEGG)
    Mineral absorption, conserved biosystemMinerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an ...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
cellular response to cadmium ion IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to zinc ion IEP
Inferred from Expression Pattern
more info
PubMed 
negative regulation of growth ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
metallothionein-1E
Names
metallothionein-1E
metallothionein 1E (functional)
metallothionein D
metallothionein-IE

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175617.3NP_783316.2  metallothionein-1E

    See identical proteins and their annotated locations for NP_783316.2

    Status: VALIDATED

    Source sequence(s)
    BC009699
    Consensus CDS
    CCDS10764.2
    UniProtKB/Swiss-Prot
    P04732
    Conserved Domains (1) summary
    pfam00131
    Location:559
    Metallothio; Metallothionein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p2 Primary Assembly

    Range
    56625673..56627112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005255956.3XP_005256013.1  

    See identical proteins and their annotated locations for XP_005256013.1

    UniProtKB/Swiss-Prot
    P04732
    Conserved Domains (1) summary
    pfam00131
    Location:535
    Metallothio; Metallothionein

Alternate CHM1_1.1

Genomic

  1. NC_018927.2 Alternate CHM1_1.1

    Range
    58066488..58067927
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)