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    Map2 microtubule-associated protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 17756, updated on 5-Apr-2024

    Summary

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    Official Symbol
    Map2provided by MGI
    Official Full Name
    microtubule-associated protein 2provided by MGI
    Primary source
    MGI:MGI:97175
    See related
    Ensembl:ENSMUSG00000015222 AllianceGenome:MGI:97175
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MAP-2; Mtap2; Mtap-2; repro4; G1-397-34
    Summary
    Enables microtubule binding activity. Involved in microtubule cytoskeleton organization; negative regulation of axon extension; and regulation of protein localization. Acts upstream of or within several processes, including establishment of cell polarity; microtubule bundle formation; and neuron projection development. Located in several cellular components, including axon; dendrite; and proximal neuron projection. Is expressed in several structures, including back skin; central nervous system; peripheral nervous system ganglion; retina; and trigeminal nerve. Orthologous to human MAP2 (microtubule associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in CNS E18 (RPKM 41.7), frontal lobe adult (RPKM 39.0) and 6 other tissues See more
    Orthologs
    human all
    NEW
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    Genomic context

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    See Map2 in Genome Data Viewer
    Location:
    1 C3; 1 33.49 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (66214337..66481742)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (66175202..66442583)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene cell growth-regulating nucleolar protein Neighboring gene STARR-seq mESC enhancer starr_01184 Neighboring gene predicted gene 8812 Neighboring gene STARR-seq mESC enhancer starr_01185 Neighboring gene predicted gene, 51629 Neighboring gene predicted gene, 24729 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene STARR-seq mESC enhancer starr_01187 Neighboring gene STARR-seq mESC enhancer starr_01188 Neighboring gene predicted gene, 25411 Neighboring gene STARR-seq mESC enhancer starr_01189 Neighboring gene unc-80, NALCN activator Neighboring gene STARR-seq mESC enhancer starr_01190 Neighboring gene predicted gene, 39655 Neighboring gene KAT8 regulatory NSL complex subunit 1-like Neighboring gene ribulose-5-phosphate-3-epimerase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. MAP2 is differentially phosphorylated in schizophrenia, altering its function. Grubisha MJ, et al. Mol Psychiatry, 2021 Sep. PMID 33526823, Free PMC Article
    2. A Mutation in Mtap2 Is Associated with Arrest of Mammalian Spermatocytes before the First Meiotic Division. Sun F, et al. Genes (Basel), 2011 Mar 1. PMID 24501684, Free PMC Article
    3. Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses. Takahashi RH, et al. PLoS One, 2013. PMID 23372648, Free PMC Article
    4. Reduced expression of kinase-associated phosphatase in cortical dendrites of MAP2-deficient mice. Iriuchijima N, et al. Biochem Biophys Res Commun, 2005 Dec 16. PMID 16257389
    5. Transient loss of microtubule-associated protein 2 immunoreactivity after moderate brain injury in mice. Huh JW, et al. J Neurotrauma, 2003 Oct. PMID 14588114

    See all (527) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MAP2 is differentially phosphorylated in schizophrenia, altering its function.
      Title: MAP2 is differentially phosphorylated in schizophrenia, altering its function.
    2. Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.
      Title: Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.
    3. MAP2c levels in different brain regions of aging mice were positively correlated with neuropsin expression.
      Title: Neuropsin Expression Correlates with Dendritic Marker MAP2c Level in Different Brain Regions of Aging Mice.
    4. Accumulation of intraneuronal beta-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses.
      Title: Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses.
    5. results demonstrate the structural and functional determinant underlying the v-KIND-MAP2 interaction that controls dendrite arborization patterns
      Title: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain.
    6. Increased MAP2 expression in malignant melanoma cells significantly inhibits tumor cell growth and neoplasm invasiveness, and induces apoptosis and cell cycle arrest.
      Title: Increased expression of MAP2 inhibits melanoma cell proliferation, invasion and tumor growth in vitro and in vivo.
    7. Data show that inhibition of ZNF238 (RP58) expression in mouse GNPs decreases the expression of the neuronal differentiation markers MAP2 and NeuN and downregulates the expression of the cell cycle arrest protein p27, a regulator of GNP differentiation.
      Title: ZNF238 is expressed in postmitotic brain cells and inhibits brain tumor growth.
    8. AKAP150 and Mtap2 put TREK channels at the center of a complex protein network that finely tunes channel trafficking, addressing, and regulation.
      Title: Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.
    9. v-KIND mediates a signaling pathway that links Ras and MAP2 to control dendrite growth
      Title: Very-KIND, a KIND domain containing RasGEF, controls dendrite growth by linking Ras small GTPases and MAP2.
    10. JNK1 phosphorylation of MAP2 plays an important role in defining dendritic architecture in the brain.
      Title: Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector.
    Submit: New GeneRIF Correction See all GeneRIFs (18)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3)  1 citation
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (4) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytoskeletal regulatory protein binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables dystroglycan binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables tubulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within axonogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to organic substance IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within dendrite development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within establishment of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule bundle formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of axon extension IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of axon extension ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of microtubule depolymerization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of microtubule polymerization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of anterograde dense core granule transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of anterograde synaptic vesicle transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of organelle transport along microtubule ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of protein localization ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in CA3 pyramidal cell dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in apical dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in apical distal dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in axon hillock IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in axon hillock ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in axon initial segment IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in axon initial segment ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in basal dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    located_in dendrite cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendritic branch ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendritic filopodium ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendritic growth cone ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendritic shaft IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendritic shaft ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in distal dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intracellular anatomical structure IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of microtubule associated complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuron projection ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in postsynapse ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in primary dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in proximal dendrite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in proximal neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in proximal neuron projection ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in ruffle membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    microtubule-associated protein 2

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039934.1 → NP_001035023.1  microtubule-associated protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001035023.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR, lacks a large in-frame segment, and contains an alternate in-frame exon compared to variant 3. The resulting isoform (1) has the same N- and C-termini but is much shorter compared to isoform 3.
      Source sequence(s)
      AC091465, AW124823, BU056737, CD348897, CN533265, CN538992
      Consensus CDS
      CCDS15020.1
      UniProtKB/TrEMBL
      B2KGT5, Q3TLQ0, Q80X35
      Related
      ENSMUSP00000109650.2, ENSMUST00000114017.8
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    2. NM_001310634.1 → NP_001297563.1  microtubule-associated protein 2 isoform 3

      See identical proteins and their annotated locations for NP_001297563.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
      Source sequence(s)
      AK141458, BC052446, CF538767, CV558214
      Consensus CDS
      CCDS83550.1
      UniProtKB/Swiss-Prot
      E9QLE1, P20357
      UniProtKB/TrEMBL
      A0A668KLC6
      Related
      ENSMUSP00000109646.2, ENSMUST00000114013.8
      Conserved Domains (2) summary
      pfam00418
      Location:1693 → 1722
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    3. NM_008632.2 → NP_032658.2  microtubule-associated protein 2 isoform 2

      See identical proteins and their annotated locations for NP_032658.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and lacks a large in-frame segment compared to variant 3. The resulting isoform (2) has the same N- and C-termini but is much shorter compared to isoform 3.
      Source sequence(s)
      BC052446
      Consensus CDS
      CCDS35602.1
      UniProtKB/TrEMBL
      B2KGT5, Q80X35, Q80ZL4
      Related
      ENSMUSP00000109648.2, ENSMUST00000114015.8
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      66214337..66481742
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006495762.5 → XP_006495825.1  microtubule-associated protein 2 isoform X17

      See identical proteins and their annotated locations for XP_006495825.1

      UniProtKB/TrEMBL
      B2KGT5, Q80X35, Q80ZL4
      Related
      ENSMUSP00000024639.6, ENSMUST00000024639.12
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    2. XM_036162607.1 → XP_036018500.1  microtubule-associated protein 2 isoform X19

      UniProtKB/TrEMBL
      A0A668KLC6
      Related
      ENSMUSP00000159224.2, ENSMUST00000239213.2
      Conserved Domains (2) summary
      pfam08377
      Location:458 → 1592
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1806 → 1837
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    3. XM_006495746.4 → XP_006495809.1  microtubule-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006495809.1

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1693 → 1722
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    4. XM_006495754.4 → XP_006495817.1  microtubule-associated protein 2 isoform X7

      See identical proteins and their annotated locations for XP_006495817.1

      UniProtKB/Swiss-Prot
      E9QLE1, P20357
      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1693 → 1722
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    5. XM_006495751.4 → XP_006495814.1  microtubule-associated protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1692 → 1721
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    6. XM_006495756.4 → XP_006495819.1  microtubule-associated protein 2 isoform X9

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1692 → 1721
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    7. XM_006495750.4 → XP_006495813.1  microtubule-associated protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1692 → 1721
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1509
      MAP2_projctn; MAP2/Tau projection domain

    8. XM_017319166.3 → XP_017174655.1  microtubule-associated protein 2 isoform X8

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1692 → 1721
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1509
      MAP2_projctn; MAP2/Tau projection domain

    9. XM_006495752.4 → XP_006495815.1  microtubule-associated protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1691 → 1720
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1509
      MAP2_projctn; MAP2/Tau projection domain

    10. XM_017319175.3 → XP_017174664.1  microtubule-associated protein 2 isoform X10

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1691 → 1720
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1509
      MAP2_projctn; MAP2/Tau projection domain

    11. XM_006495753.4 → XP_006495816.1  microtubule-associated protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam08377
      Location:372 → 1506
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1689 → 1719
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    12. XM_006495757.4 → XP_006495820.1  microtubule-associated protein 2 isoform X11

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1689 → 1718
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:372 → 1506
      MAP2_projctn; MAP2/Tau projection domain

    13. XM_036162582.1 → XP_036018475.1  microtubule-associated protein 2 isoform X13

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam08377
      Location:372 → 1506
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1719 → 1750
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    14. XM_036162575.1 → XP_036018468.1  microtubule-associated protein 2 isoform X6

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam08377
      Location:372 → 1505
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1688 → 1718
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    15. XM_036162581.1 → XP_036018474.1  microtubule-associated protein 2 isoform X12

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam08377
      Location:372 → 1505
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1719 → 1750
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    16. XM_006495759.5 → XP_006495822.1  microtubule-associated protein 2 isoform X15

      See identical proteins and their annotated locations for XP_006495822.1

      UniProtKB/TrEMBL
      B2KGT5, Q3TLQ0, Q80X35
      Related
      ENSMUSP00000109651.4, ENSMUST00000114018.10
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    17. XM_006495761.5 → XP_006495824.1  microtubule-associated protein 2 isoform X16

      UniProtKB/TrEMBL
      B2KGT5, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:331 → 360
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    18. XM_036162601.1 → XP_036018494.1  microtubule-associated protein 2 isoform X18

      UniProtKB/TrEMBL
      B2KGT5, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:362 → 393
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    19. XM_011238448.3 → XP_011236750.1  microtubule-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011236750.1

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1693 → 1722
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    20. XM_030251990.2 → XP_030107850.1  microtubule-associated protein 2 isoform X16

      UniProtKB/TrEMBL
      B2KGT5, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:331 → 360
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    21. XM_030251982.1 → XP_030107842.1  microtubule-associated protein 2 isoform X15

      UniProtKB/TrEMBL
      B2KGT5, Q3TLQ0, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    22. XM_006495748.5 → XP_006495811.1  microtubule-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006495811.1

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1693 → 1722
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    23. XM_006495749.5 → XP_006495812.1  microtubule-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006495812.1

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1693 → 1722
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    24. XM_036162573.1 → XP_036018466.1  microtubule-associated protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam08377
      Location:372 → 1506
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1689 → 1719
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    25. XM_030251986.2 → XP_030107846.1  microtubule-associated protein 2 isoform X15

      UniProtKB/TrEMBL
      B2KGT5, Q3TLQ0, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    26. XM_030251996.2 → XP_030107856.1  microtubule-associated protein 2 isoform X17

      UniProtKB/TrEMBL
      B2KGT5, Q80X35, Q80ZL4
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    27. XM_030251993.2 → XP_030107853.1  microtubule-associated protein 2 isoform X16

      UniProtKB/TrEMBL
      B2KGT5, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:331 → 360
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    28. XM_006495747.5 → XP_006495810.1  microtubule-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006495810.1

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1693 → 1722
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    29. XM_017319165.3 → XP_017174654.1  microtubule-associated protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1692 → 1721
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    30. XM_017319169.3 → XP_017174658.1  microtubule-associated protein 2 isoform X9

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1692 → 1721
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:376 → 1510
      MAP2_projctn; MAP2/Tau projection domain

    31. XM_030251971.2 → XP_030107831.1  microtubule-associated protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam08377
      Location:372 → 1506
      MAP2_projctn; MAP2/Tau projection domain
      pfam00418
      Location:1689 → 1719
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    32. XM_006495760.3 → XP_006495823.1  microtubule-associated protein 2 isoform X15

      See identical proteins and their annotated locations for XP_006495823.1

      UniProtKB/TrEMBL
      B2KGT5, Q3TLQ0, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    33. XM_017319194.3 → XP_017174683.1  microtubule-associated protein 2 isoform X17

      UniProtKB/TrEMBL
      B2KGT5, Q80X35, Q80ZL4
      Conserved Domains (1) summary
      pfam00418
      Location:332 → 361
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    34. XM_030251989.2 → XP_030107849.1  microtubule-associated protein 2 isoform X16

      UniProtKB/TrEMBL
      B2KGT5, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:331 → 360
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    35. XM_036162604.1 → XP_036018497.1  microtubule-associated protein 2 isoform X18

      UniProtKB/TrEMBL
      B2KGT5, Q80X35
      Conserved Domains (1) summary
      pfam00418
      Location:362 → 393
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

    36. XM_006495758.5 → XP_006495821.1  microtubule-associated protein 2 isoform X14

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1535 → 1564
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:218 → 1352
      MAP2_projctn; MAP2/Tau projection domain

    37. XM_030251978.2 → XP_030107838.1  microtubule-associated protein 2 isoform X14

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1535 → 1564
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:218 → 1352
      MAP2_projctn; MAP2/Tau projection domain

    38. XM_030251976.2 → XP_030107836.1  microtubule-associated protein 2 isoform X14

      UniProtKB/TrEMBL
      A0A668KLC6
      Conserved Domains (2) summary
      pfam00418
      Location:1535 → 1564
      Tubulin-binding; Tau and MAP protein, tubulin-binding repeat
      pfam08377
      Location:218 → 1352
      MAP2_projctn; MAP2/Tau projection domain

    RNA

    1. XR_004940738.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20357.2 GenPept UniProtKB/Swiss-Prot:P20357

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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