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    USP9Y ubiquitin specific peptidase 9, Y-linked [ Homo sapiens (human) ]

    Gene ID: 8287, updated on 13-Aug-2016
    Official Symbol
    USP9Yprovided by HGNC
    Official Full Name
    ubiquitin specific peptidase 9, Y-linkedprovided by HGNC
    Primary source
    HGNC:HGNC:12633
    See related
    Ensembl:ENSG00000114374 HPRD:02449; MIM:400005; Vega:OTTHUMG00000036469
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DFFRY; SPGFY2
    Summary
    This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq, Mar 2009]
    Orthologs
    Location:
    Yq11.2
    Exon count:
    47
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) Y NC_000024.10 (12701231..12860844)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) Y NC_000024.9 (14813160..14972768)

    Chromosome Y - NC_000024.10Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 14 pseudogene 1 Neighboring gene testis-specific transcript, Y-linked 15 (non-protein coding) Neighboring gene chromodomain Y-linked 4 pseudogene Neighboring gene DEAD-box helicase 3, Y-linked Neighboring gene calcium/calmodulin dependent serine protein kinase pseudogene 1

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • FLJ33043

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    co-SMAD binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cysteine-type peptidase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    thiol-dependent ubiquitin-specific protease activity TAS
    Traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    BMP signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    protein deubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    spermatogenesis TAS
    Traceable Author Statement
    more info
    PubMed 
    transforming growth factor beta receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Preferred Names
    probable ubiquitin carboxyl-terminal hydrolase FAF-Y
    Names
    deubiquitinating enzyme FAF-Y
    fat facets protein-related, Y-linked
    ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila)
    ubiquitin thioesterase FAF-Y
    ubiquitin thiolesterase FAF-Y
    ubiquitin-specific processing protease FAF-Y
    ubiquitin-specific protease 9, Y chromosome
    ubiquitin-specific-processing protease FAF-Y
    NP_004645.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_008311.1 RefSeqGene

      Range
      5001..164609
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_004654.3NP_004645.2  probable ubiquitin carboxyl-terminal hydrolase FAF-Y

      See identical proteins and their annotated locations for NP_004645.2

      Status: REVIEWED

      Source sequence(s)
      AF000986, BI754571, CK823170, Y13618
      Consensus CDS
      CCDS14781.1
      UniProtKB/Swiss-Prot
      O00507
      Related
      ENSP00000342812, OTTHUMP00000034631, ENST00000338981, OTTHUMT00000088703
      Conserved Domains (2) summary
      cd02659
      Location:15571960
      peptidase_C19C; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam00443
      Location:15591955
      UCH; Ubiquitin carboxyl-terminal hydrolase

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000024.10 Reference GRCh38.p7 Primary Assembly

      Range
      12701231..12860844
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017030078.1XP_016885567.1