PubMed for id: 22059

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p53 regulates diverse tissue-specific outcomes to endogenous DNA damage in mice.

Hill RJ, Bona N, Smink J, Webb HK, Crisp A, Garaycoechea JI, Crossan GP. Hill RJ, et al. Nat Commun. 2024 Mar 21;15(1):2518. doi: 10.1038/s41467-024-46844-1. Nat Commun. 2024. PMID: 38514641 Free PMC article.

Hippo cooperates with p53 to maintain foregut homeostasis and suppress the malignant transformation of foregut basal progenitor cells.

Jiang Y, Huang H, Liu J, Luo D, Mu R, Yuan J, Lin J, Chen Q, Tao W, Yang L, Zhang M, Zhang P, Fang F, Xu J, Gong Q, Xie Z, Zhang Y. Jiang Y, et al. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2320559121. doi: 10.1073/pnas.2320559121. Epub 2024 Feb 26. Proc Natl Acad Sci U S A. 2024. PMID: 38408237

p53 promotes antiviral innate immunity by driving hexosamine metabolism.

Xia W, Jiang P. Xia W, et al. Cell Rep. 2024 Feb 27;43(2):113724. doi: 10.1016/j.celrep.2024.113724. Epub 2024 Jan 30. Cell Rep. 2024. PMID: 38294905 Free article.

Genomic and functional impact of Trp53 inactivation in JAK2V617F myeloproliferative neoplasms.

Gou P, Liu D, Ganesan S, Lauret E, Maslah N, Parietti V, Zhang W, Meignin V, Kiladjian JJ, Cassinat B, Giraudier S. Gou P, et al. Blood Cancer J. 2024 Jan 4;14(1):1. doi: 10.1038/s41408-023-00969-6. Blood Cancer J. 2024. PMID: 38177095 Free PMC article.

Regulation of the innate immune response and gut microbiome by p53.

Khor AHP, Koguchi T, Liu H, Kakuta M, Matsubara D, Wen R, Sagiya Y, Imoto S, Nakagawa H, Matsuda K, Tanikawa C. Khor AHP, et al. Cancer Sci. 2024 Jan;115(1):184-196. doi: 10.1111/cas.15991. Epub 2023 Dec 4. Cancer Sci. 2024. PMID: 38050344 Free PMC article.

Arsenic trioxide extends survival of Li-Fraumeni syndrome mimicking mouse.

Li J, Xiao S, Shi F, Song H, Wu J, Zheng D, Chen X, Tan K, Lu M. Li J, et al. Cell Death Dis. 2023 Nov 29;14(11):783. doi: 10.1038/s41419-023-06281-2. Cell Death Dis. 2023. PMID: 38030599 Free PMC article.

Extensive elimination of acinar cells during normal postnatal pancreas growth.

Stolovich-Rain M, Fridlich O, Azulai S, Klochendler A, Anzi S, Magenheim J, Stein I, Mushasha F, Glaser B, Pikarsky E, Ben-Zvi D, Dor Y. Stolovich-Rain M, et al. Cell Rep. 2023 Dec 26;42(12):113457. doi: 10.1016/j.celrep.2023.113457. Epub 2023 Nov 22. Cell Rep. 2023. PMID: 37995187 Free article.

Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells.

Wang Z, Burigotto M, Ghetti S, Vaillant F, Tan T, Capaldo BD, Palmieri M, Hirokawa Y, Tai L, Simpson DS, Chang C, Huang AS, Lieschke E, Diepstraten ST, Kaloni D, Riffkin C, Huang DCS, Li Wai Suen CSN, Garnham AL, Gibbs P, Visvader JE, Sieber OM, Herold MJ, Fava LL, Kelly GL, Strasser A. Wang Z, et al. Cancer Discov. 2024 Feb 8;14(2):362-379. doi: 10.1158/2159-8290.CD-23-0402. Cancer Discov. 2024. PMID: 37877779 Free PMC article.

Gain-of-Function p53 Mutation Acts as a Genetic Switch for TGFβ Signaling-Induced Epithelial-to-Mesenchymal Transition in Intestinal Tumors.

Wang D, Nakayama M, Hong CP, Oshima H, Oshima M. Wang D, et al. Cancer Res. 2024 Jan 2;84(1):56-68. doi: 10.1158/0008-5472.CAN-23-1490. Cancer Res. 2024. PMID: 37851521 Free PMC article.

TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.

Ausejo-Mauleon I, Labiano S, de la Nava D, Laspidea V, Zalacain M, Marrodán L, García-Moure M, González-Huarriz M, Hervás-Corpión I, Dhandapani L, Vicent S, Collantes M, Peñuelas I, Becher OJ, Filbin MG, Jiang L, Labelle J, de Biagi-Junior CAO, Nazarian J, Laternser S, Phoenix TN, van der Lugt J, Kranendonk M, Hoogendijk R, Mueller S, De Andrea C, Anderson AC, Guruceaga E, Koschmann C, Yadav VN, Gállego Pérez-Larraya J, Patiño-García A, Pastor F, Alonso MM. Ausejo-Mauleon I, et al. Cancer Cell. 2023 Nov 13;41(11):1911-1926.e8. doi: 10.1016/j.ccell.2023.09.001. Epub 2023 Oct 5. Cancer Cell. 2023. PMID: 37802053 Free PMC article.

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