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    Adgre1 adhesion G protein-coupled receptor E1 [ Mus musculus (house mouse) ]

    Gene ID: 13733, updated on 25-Jul-2015
    Official Symbol
    Adgre1provided by MGI
    Official Full Name
    adhesion G protein-coupled receptor E1provided by MGI
    Primary source
    MGI:MGI:106912
    See related
    Ensembl:ENSMUSG00000004730
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Emr1; Ly71; F4/80; Gpf480; TM7LN3; DD7A5-7; EGF-TM7
    Orthologs
    See Adgre1 in Epigenomics, MapViewer
    Location:
    17 D; 17 29.8 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    105 current GRCm38.p3 (GCF_000001635.23) 17 NC_000083.6 (57358651..57483529)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (57498109..57622952)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene thyroid hormone receptor interactor 10 Neighboring gene G protein-coupled receptor 108 Neighboring gene vav 1 oncogene Neighboring gene U1 small nuclear ribonucleoprotein C pseudogene Neighboring gene heat shock protein 8 pseudogene Neighboring gene vomeronasal 2, receptor 120 Neighboring gene histone deacetylase 1 pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Chemically induced (ENU) (2) 

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell periphery IDA
    Inferred from Direct Assay
    more info
    PubMed 
    external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    adhesion G protein-coupled receptor E1
    Names
    EGF-like module containing, mucin-like, hormone receptor-like sequence 1
    EGF-like module receptor 1
    EGF-like module-containing mucin-like hormone receptor-like 1
    EMR1 hormone receptor
    cell surface glycoprotein F4/80
    lymphocyte antigen 71

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010130.4NP_034260.1  adhesion G protein-coupled receptor E1 precursor

      See identical proteins and their annotated locations for NP_034260.1

      Status: VALIDATED

      Source sequence(s)
      AK133202, BY197649, BY493080
      Consensus CDS
      CCDS50160.1
      UniProtKB/TrEMBL
      Q3U9R0
      UniProtKB/Swiss-Prot
      Q61549
      Related
      ENSMUSP00000083971, ENSMUST00000086763
      Conserved Domains (3) summary
      smart00303
      Location:591640
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:222258
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00002
      Location:645885
      7tm_2; 7 transmembrane receptor (Secretin family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p3 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p3 C57BL/6J

      Range
      57358651..57483529
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523601.1XP_006523664.1  

      See identical proteins and their annotated locations for XP_006523664.1

      UniProtKB/TrEMBL
      Q3U9R0
      UniProtKB/Swiss-Prot
      Q61549
      Related
      ENSMUSP00000004850, ENSMUST00000004850
      Conserved Domains (3) summary
      smart00303
      Location:591640
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:222258
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00002
      Location:645885
      7tm_2; 7 transmembrane receptor (Secretin family)
    2. XM_011246272.1XP_011244574.1  

      Conserved Domains (3) summary
      smart00303
      Location:575624
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:206242
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00002
      Location:629869
      7tm_2; 7 transmembrane receptor (Secretin family)
    3. XM_006523602.1XP_006523665.1  

      Conserved Domains (3) summary
      smart00303
      Location:450499
      GPS; G-protein-coupled receptor proteolytic site domain
      cd00054
      Location:81117
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00002
      Location:504744
      7tm_2; 7 transmembrane receptor (Secretin family)

    Alternate Mm_Celera

    Genomic

    1. AC_000039.1 Alternate Mm_Celera

      Range
      61708492..61834039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)