Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Nqo1 NAD(P)H dehydrogenase, quinone 1 [ Mus musculus (house mouse) ]

    Gene ID: 18104, updated on 9-Aug-2016
    Official Symbol
    Nqo1provided by MGI
    Official Full Name
    NAD(P)H dehydrogenase, quinone 1provided by MGI
    Primary source
    MGI:MGI:103187
    See related
    Ensembl:ENSMUSG00000003849 Vega:OTTMUSG00000022884
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dtd; Ox1; Qr1; Dia4; Nmo1; Ox-1; Nmo-1; Nmor1; AV001255
    Orthologs
    Location:
    8 D3; 8 54.08 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (107388225..107403205, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (109912125..109927105, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein S18, pseudogene 3 Neighboring gene nuclear factor of activated T cells 5 Neighboring gene NIN1/RPN12 binding protein 1 homolog Neighboring gene ribosomal protein S26, pseudogene 1 Neighboring gene WW domain containing E3 ubiquitin protein ligase 2

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NAD(P)H dehydrogenase (quinone) activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NAD(P)H dehydrogenase (quinone) activity ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    poly(A) RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    superoxide dismutase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of catalytic activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    superoxide metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    NAD(P)H dehydrogenase [quinone] 1
    Names
    DT-diaphorase
    NAD(P)H dehydrogenase (quinone)
    NAD(P)H menadione oxidoreductase 1, dioxin inducible
    NAD(P)H:quinone oxidoreductase 1
    azoreductase
    diaphorase 4 (NADH/NADPH)
    menadione reductase
    phylloquinone reductase
    quinone reductase 1
    NP_032732.3

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008706.5NP_032732.3  NAD(P)H dehydrogenase [quinone] 1

      See identical proteins and their annotated locations for NP_032732.3

      Status: VALIDATED

      Source sequence(s)
      AA982077, AK075568
      Consensus CDS
      CCDS40465.1
      UniProtKB/Swiss-Prot
      Q64669
      UniProtKB/TrEMBL
      Q542Y0
      Related
      ENSMUSP00000003947, OTTMUSP00000026299, ENSMUST00000003947, OTTMUST00000055042
      Conserved Domains (1) summary
      pfam02525
      Location:5212
      Flavodoxin_2; Flavodoxin-like fold

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      107388225..107403205 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)