Display Settings:

Format

Send to:

Choose Destination

Uchl1 ubiquitin carboxy-terminal hydrolase L1 [ Mus musculus (house mouse) ]

Gene ID: 22223, updated on 7-Aug-2014
Official Symbol
Uchl1provided by MGI
Official Full Name
ubiquitin carboxy-terminal hydrolase L1provided by MGI
Primary source
MGI:103149
See related
Ensembl:ENSMUSG00000029223; Vega:OTTMUSG00000042268
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
gad; C88048; PGP9.5; R75593; UCH-L1; UCHL-1; PGP 9.5; AW822034
See Uchl1 in Epigenomics, MapViewer
Location:
5 C3.1; 5 35.95 cM
Exon count:
9
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 5 NC_000071.6 (66676121..66687234)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene NOL1/NOP2/Sun domain family, member 7 Neighboring gene amyloid beta (A4) precursor protein-binding, family B, member 2 Neighboring gene uncharacterized LOC102635692 Neighboring gene ubiquitin carboxy-terminal hydrolase L1, opposite strand Neighboring gene LIM and calponin homology domains 1 Neighboring gene predicted gene 6517 Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
alpha-2A adrenergic receptor binding ISO
Inferred from Sequence Orthology
more info
 
cysteine-type endopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
omega peptidase activity ISO
Inferred from Sequence Orthology
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin binding IDA
Inferred from Direct Assay
more info
PubMed 
ubiquitin binding ISO
Inferred from Sequence Orthology
more info
 
ubiquitin thiolesterase activity IDA
Inferred from Direct Assay
more info
PubMed 
ubiquitin-specific protease activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
adult walking behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
adult walking behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
axon target recognition IMP
Inferred from Mutant Phenotype
more info
PubMed 
axon transport of mitochondrion IMP
Inferred from Mutant Phenotype
more info
PubMed 
axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
eating behavior IGI
Inferred from Genetic Interaction
more info
PubMed 
muscle fiber development IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of MAP kinase activity ISO
Inferred from Sequence Orthology
more info
 
neuromuscular process IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein deubiquitination ISO
Inferred from Sequence Orthology
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
response to ischemia IMP
Inferred from Mutant Phenotype
more info
PubMed 
sensory perception of pain ISO
Inferred from Sequence Orthology
more info
 
ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
axon IDA
Inferred from Direct Assay
more info
PubMed 
cell IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
intracellular IMP
Inferred from Mutant Phenotype
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
ubiquitin carboxyl-terminal hydrolase isozyme L1
Names
ubiquitin carboxyl-terminal hydrolase isozyme L1
gracile axonal dystrophy
protein gene product 9.5
ubiquitin thioesterase L1
neuron cytoplasmic protein 9.5
NP_035800.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011670.2NP_035800.2  ubiquitin carboxyl-terminal hydrolase isozyme L1

    See proteins identical to NP_035800.2

    Status: VALIDATED

    Source sequence(s)
    AF172334, AK013729, CX241178
    Consensus CDS
    CCDS19315.1
    UniProtKB/Swiss-Prot
    Q9R0P9
    Related
    ENSMUSP00000031131, OTTMUSP00000062165, ENSMUST00000031131, OTTMUST00000111175
    Conserved Domains (1) summary
    cd09616
    Location:5219
    Blast Score: 905
    Peptidase_C12_UCH_L1_L3; Cysteine peptidase C12 containing ubiquitin carboxyl-terminal hydrolase (UCH) families L1 and L3

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000071.6 

    Range
    66676121..66687234
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 

    Range
    63976841..63987914
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)