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Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial [ Mus musculus (house mouse) ]

Gene ID: 14571, updated on 19-Sep-2014
Official Symbol
Gpd2provided by MGI
Official Full Name
glycerol phosphate dehydrogenase 2, mitochondrialprovided by MGI
Primary source
MGI:MGI:99778
See related
Ensembl:ENSMUSG00000026827; Vega:OTTMUSG00000012561
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GPDH; Gdm1; Gpd-m; Gpdh-m; TISP38; AA408484; AI448216; AU021455; AW494132
See Gpd2 in Epigenomics, MapViewer
Location:
2 C1.1; 2 31.66 cM
Exon count:
18
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 2 NC_000068.7 (57237678..57370719)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930555B11 gene Neighboring gene nuclear encoded tRNA alanine 27 (anticodon CGC) Neighboring gene nuclear encoded tRNA glycine 29 (anticodon GCC) Neighboring gene RIKEN cDNA A930012O16 gene Neighboring gene cytoskeleton associated protein 2 pseudogene Neighboring gene predicted gene 13531 Neighboring gene heterogeneous nuclear ribonucleoprotein F pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
glycerol-3-phosphate dehydrogenase [NAD+] activity ISO
Inferred from Sequence Orthology
more info
 
glycerol-3-phosphate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
NADH metabolic process ISO
Inferred from Sequence Orthology
more info
 
camera-type eye development IGI
Inferred from Genetic Interaction
more info
 
gluconeogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycerol-3-phosphate metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycerol-3-phosphate metabolic process ISO
Inferred from Sequence Orthology
more info
 
multicellular organism growth IGI
Inferred from Genetic Interaction
more info
 
oxidation-reduction process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
glycerol-3-phosphate dehydrogenase complex TAS
Traceable Author Statement
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
glycerol-3-phosphate dehydrogenase, mitochondrial
Names
glycerol-3-phosphate dehydrogenase, mitochondrial
FAD-linked glycerol-3-phosphate dehydrogenase
glycerol phosphate dehydrogenase 1, mitochondrial
glycerol-3-phosphate dehydrogenase 2, mitochondrial
NP_001139292.1
NP_034404.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145820.1NP_001139292.1  glycerol-3-phosphate dehydrogenase, mitochondrial precursor

    See proteins identical to NP_001139292.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants encode the same protein.
    Source sequence(s)
    AK032044, AK080240, AK144716
    Consensus CDS
    CCDS16045.1
    UniProtKB/Swiss-Prot
    Q64521
    Related
    ENSMUSP00000130992, ENSMUST00000169687
    Conserved Domains (4) summary
    PLN02464
    Location:1599
    PLN02464; glycerol-3-phosphate dehydrogenase
    cd00051
    Location:627689
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:634688
    EF-hand_7; EF-hand domain pair
    cl19134
    Location:87569
    NAD_binding_8; NAD(P)-binding Rossmann-like domain
  2. NM_010274.3NP_034404.3  glycerol-3-phosphate dehydrogenase, mitochondrial precursor

    See proteins identical to NP_034404.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants encode the same protein.
    Source sequence(s)
    AK032044, AK080240, AK144716, BY238564
    Consensus CDS
    CCDS16045.1
    UniProtKB/Swiss-Prot
    Q64521
    Related
    ENSMUSP00000028167, ENSMUST00000028167
    Conserved Domains (4) summary
    PLN02464
    Location:1599
    PLN02464; glycerol-3-phosphate dehydrogenase
    cd00051
    Location:627689
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:634688
    EF-hand_7; EF-hand domain pair
    cl19134
    Location:87569
    NAD_binding_8; NAD(P)-binding Rossmann-like domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000068.7 

    Range
    57237678..57370719
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000024.1 

    Range
    58979703..59113189
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)