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Pink1 PTEN-induced putative kinase 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31607, updated on 7-Dec-2014
Official Symbol
Pink1provided by FlyBase
Official Full Name
PTEN-induced putative kinase 1provided by FlyBase
Primary source
FLYBASE:FBgn0029891
Locus tag
Dmel_CG4523
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:GH23468; CG4523; Dmel\CG4523; dPink1; dPINK1; PINK; pink1; PINK1
See Pink1 in Epigenomics, MapViewer
Location:
6C6-6C6
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.01 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (6683798..6687302)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6577831..6581335)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene CG3192 gene product from transcript CG3192-RA Neighboring gene lethal (1) G0255 Neighboring gene CG4095 gene product from transcript CG4095-RA Neighboring gene CG44303 gene product from transcript CG44303-RA Neighboring gene CG3184 gene product from transcript CG3184-RA Neighboring gene CG14442 gene product from transcript CG14442-RA

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein kinase activity NAS
Non-traceable Author Statement
more info
 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
compound eye development IMP
Inferred from Mutant Phenotype
more info
PubMed 
ectopic germ cell programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrial fission IGI
Inferred from Genetic Interaction
more info
PubMed 
mitochondrion degradation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitochondrion organization IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion organization IGI
Inferred from Genetic Interaction
more info
PubMed 
mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of mitochondrial fusion IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of neuron apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of programmed cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuromuscular synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of mitochondrial fission IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein ubiquitination involved in ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
sperm mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Nebenkern IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
CG4523 gene product from transcript CG4523-RH
Names
CG4523-PA
CG4523-PB
CG4523-PC
CG4523-PD
CG4523-PE
CG4523-PF
CG4523-PG
CG4523-PH
CG4523-PI
PTEN induced putative kinase 1
PTEN-induced kinase 1
PTEN-induced putative kinase 1
Pink1-PA
Pink1-PB
Pink1-PC
Pink1-PD
Pink1-PE
Pink1-PF
Pink1-PG
Pink1-PH
Pink1-PI
phosphatase and tensin homolog-induced putative kinase 1
NP_001027049.1
NP_001027050.1
NP_001027051.1
NP_001027052.1
NP_001027053.1
NP_001027054.1
NP_001284952.1
NP_572340.2
NP_727110.1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 

    Range
    6683798..6687302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001031878.2NP_001027049.1  PTEN-induced putative kinase 1, isoform H [Drosophila melanogaster]

    See proteins identical to NP_001027049.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Related
    FBpp0099837, FBtr0100420
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases
  2. NM_001031880.3NP_001027051.1  PTEN-induced putative kinase 1, isoform F [Drosophila melanogaster]

    See proteins identical to NP_001027051.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Related
    FBpp0099833, FBtr0100416
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases
  3. NM_001031879.3NP_001027050.1  PTEN-induced putative kinase 1, isoform G [Drosophila melanogaster]

    See proteins identical to NP_001027050.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Related
    FBpp0099835, FBtr0100419
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases
  4. NM_001031881.3NP_001027052.1  PTEN-induced putative kinase 1, isoform E [Drosophila melanogaster]

    See proteins identical to NP_001027052.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Related
    FBpp0099832, FBtr0100415
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases
  5. NM_001031883.3NP_001027054.1  PTEN-induced putative kinase 1, isoform C [Drosophila melanogaster]

    See proteins identical to NP_001027054.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Related
    FBpp0099830, FBtr0100413
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases
  6. NM_132112.5NP_572340.2  PTEN-induced putative kinase 1, isoform A [Drosophila melanogaster]

    See proteins identical to NP_572340.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Related
    FBpp0070917, FBtr0070956
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases
  7. NM_167083.4NP_727110.1  PTEN-induced putative kinase 1, isoform B [Drosophila melanogaster]

    See proteins identical to NP_727110.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Related
    FBpp0070918, FBtr0070957
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases
  8. NM_001031882.3NP_001027053.1  PTEN-induced putative kinase 1, isoform D [Drosophila melanogaster]

    See proteins identical to NP_001027053.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Related
    FBpp0099831, FBtr0100414
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases
  9. NM_001298023.1NP_001284952.1  PTEN-induced putative kinase 1, isoform I [Drosophila melanogaster]

    See proteins identical to NP_001284952.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0KHV6
    Conserved Domains (1) summary
    cd00180
    Location:387628
    PKc; Catalytic domain of Protein Kinases