Display Settings:

Format

Send to:

Choose Destination

ZNF521 zinc finger protein 521 [ Homo sapiens (human) ]

Gene ID: 25925, updated on 7-Aug-2014
Official Symbol
ZNF521provided by HGNC
Official Full Name
zinc finger protein 521provided by HGNC
Primary source
HGNC:24605
See related
Ensembl:ENSG00000198795; HPRD:18350; MIM:610974; Vega:OTTHUMG00000179511
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EHZF; Evi3
See ZNF521 in Epigenomics, MapViewer
Location:
18q11.2
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 18 NC_000018.10 (25061924..25352250, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (22641888..22932214, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene ras-related C3 botulinum toxin substrate 1 pseudogene 1 Neighboring gene WW domain binding protein 2 pseudogene 1 Neighboring gene ribosomal protein S24 pseudogene 18 Neighboring gene synovial sarcoma translocation, chromosome 18

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC142182, MGC142208, DKFZp564D0764

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein domain specific binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
multicellular organismal development IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
zinc finger protein 521
Names
zinc finger protein 521
LYST-interacting protein 3
early hematopoietic zinc finger protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015461.2NP_056276.1  zinc finger protein 521

    See proteins identical to NP_056276.1

    Status: VALIDATED

    Source sequence(s)
    AF141339, AK027354, BC113622, DA102816
    Consensus CDS
    CCDS32806.1
    UniProtKB/Swiss-Prot
    Q96K83
    Related
    ENSP00000354794, OTTHUMP00000261662, ENST00000361524, OTTHUMT00000446781
    Conserved Domains (2) summary
    COG5048
    Location:128216
    Blast Score: 94
    COG5048; FOG: Zn-finger [General function prediction only]
    cl17238
    Location:785964
    Blast Score: 92
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000018.10 

    Range
    25061924..25352250
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005258241.1XP_005258298.1  

    UniProtKB/TrEMBL
    J3KTI4
    Related
    ENSP00000463000, OTTHUMP00000261763, ENST00000584787, OTTHUMT00000446952
    Conserved Domains (1) summary
    cl17238
    Location:565744
    Blast Score: 95
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...
  2. XM_006722436.1XP_006722499.1  

    Conserved Domains (2) summary
    COG5048
    Location:128216
    Blast Score: 94
    COG5048; FOG: Zn-finger [General function prediction only]
    cl17238
    Location:785964
    Blast Score: 92
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...
  3. XM_006722437.1XP_006722500.1  

    Conserved Domains (2) summary
    COG5048
    Location:128216
    Blast Score: 93
    COG5048; FOG: Zn-finger [General function prediction only]
    cl17238
    Location:785964
    Blast Score: 92
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...

Alternate HuRef

Genomic

  1. AC_000150.1 

    Range
    19498620..19787560
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018929.2 

    Range
    22568594..22858896
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)